Zobrazeno 1 - 10
of 1 112
pro vyhledávání: '"Rae M"'
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103249- (2024)
Summary: Here, we present a protocol for encapsulating DNA molecules under crowded conditions within cell-sized lipid-coated droplets. We describe steps for preparing a lipid-oil mixture and adding an aqueous solution containing DNA, which, when mixe
Externí odkaz:
https://doaj.org/article/f2fb83f588244b4781479cb5d9b691f9
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Helminth parasite infections are widespread in smallholder farming systems affecting farmers and livestock animals. There are pathogenic parasites that populate the gut of their host and coexist closely with the gut microbiota. The physical and immun
Externí odkaz:
https://doaj.org/article/f0b4d6b963b54fe38ceb1c90320db1cc
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors present an approach to connect polymer dynamics to force response by integrating optical tweezers with differential dynamic microscopy. They measure blends of ring and linear DNA and observe a resonant response, which is suppressed by the
Externí odkaz:
https://doaj.org/article/3de3e6d279ba4b59937024011ce06407
Autor:
Janet Y. Sheung, Jonathan Garamella, Stella K. Kahl, Brian Y. Lee, Ryan J. McGorty, Rae M. Robertson-Anderson
Publikováno v:
Frontiers in Physics, Vol 10 (2022)
The cytoskeleton–a composite network of biopolymers, molecular motors, and associated binding proteins–is a paradigmatic example of active matter. Particle transport through the cytoskeleton can range from anomalous and heterogeneous subdiffusion
Externí odkaz:
https://doaj.org/article/c03d9bcfe6fa490691312c3697008152
Autor:
Mehdi Shafiei Aporvari, Steven Dang, Juexin Marfai, Kara Coursey, Ryan McGorty, Rae M. Robertson-Anderson
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105122- (2022)
Summary: Dynamics of biological macromolecules, such as DNA, in crowded and confined environments are critical to understanding cellular processes such as transcription, infection, and replication. However, the combined effects of cellular confinemen
Externí odkaz:
https://doaj.org/article/834260d31f894bc98d2de315774fda33
Autor:
McCuskey, Dylan P., Achiriloaie, Raisa E., Benjamin, Claire, Kushen, Jemma, Blacklow, Isaac, Mnfy, Omar, Ross, Jennifer L., Robertson-Anderson, Rae M., Sheung, Janet Y.
The transport of macromolecules, such as DNA, through the cytoskeleton is critical to wide-ranging cellular processes from cytoplasmic streaming to transcription. The rigidity and steric hindrances imparted by the network of filaments comprising the
Externí odkaz:
http://arxiv.org/abs/2409.00569
Autor:
Ann T. Farrell, Julie Panepinto, Ankit A. Desai, Adetola A. Kassim, Jeffrey Lebensburger, Mark C. Walters, Daniel E. Bauer, Rae M. Blaylark, Donna M. DiMichele, Mark T. Gladwin, Nancy S. Green, Kathryn Hassell, Gregory J. Kato, Elizabeth S. Klings, Donald B. Kohn, Lakshmanan Krishnamurti, Jane Little, Julie Makani, Punam Malik, Patrick T. McGann, Caterina Minniti, Claudia R. Morris, Isaac Odame, Patricia Ann Oneal, Rosanna Setse, Poornima Sharma, Shalini Shenoy
Publikováno v:
Blood Advances, Vol 3, Iss 23, Pp 4002-4020 (2019)
Abstract: To address the global burden of sickle cell disease and the need for novel therapies, the American Society of Hematology partnered with the US Food and Drug Administration to engage the work of 7 panels of clinicians, investigators, and pat
Externí odkaz:
https://doaj.org/article/06caa969e3bd4e5b84bcc4cdd2e86f79
Autor:
Bekele J. Gurmessa, Michael J. Rust, Moumita Das, Jennifer L. Ross, Rae M. Robertson-Anderson
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Cells dynamically change their viscoelastic properties by restructuring networks of actin filaments in the cytoskeleton, enabling diverse mechanical processes such as mobility and apoptosis. This restructuring is modulated, in part, by actin-binding
Externí odkaz:
https://doaj.org/article/a3ea0d52cb9840bab76dc70a3a96f914
Publikováno v:
Polymers, Vol 14, Iss 22, p 4980 (2022)
Actin plays a vital role in maintaining the stability and rigidity of biological cells while allowing for cell motility and shape change. The semiflexible nature of actin filaments—along with the myriad actin-binding proteins (ABPs) that serve to c
Externí odkaz:
https://doaj.org/article/14b6ce7f108b4859baee9c956152bde3
Autor:
Yuecheng Zhou, Kai-Wen Hsiao, Kathryn E. Regan, Dejie Kong, Gregory B. McKenna, Rae M. Robertson-Anderson, Charles M. Schroeder
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Understanding the dynamics of ring polymers is challenging are despite recent progress, understanding of the nonequilibrium behavior of ring polymers has not yet been achieved. Here, the authors directly observe the flow dynamics of DNA-based rings i
Externí odkaz:
https://doaj.org/article/4f70f5e4b3284f39b53e53695e8ad3ff