Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Radwan El-Haggar"'
Autor:
Hesham Haffez, Nosaiba A. Elsayed, Marwa F. Ahmed, Samar S. Fatahala, Eman F. Khaleel, Rehab Mustafa Badi, Eslam B. Elkaeed, Mahmoud A. El Hassab, Sherif F. Hammad, Wagdy M. Eldehna, Nicolas Masurier, Radwan El-Haggar
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Significant advancements have been made in the domain of targeted anticancer therapy for the management of malignancies in recent times. VEGFR-2 is characterised by its pivotal involvement in angiogenesis and subsequent mechanisms that promote tumour
Externí odkaz:
https://doaj.org/article/8fcc8ea833f943b4862f2890cfe139e0
Autor:
Rofida Albash, Maha H. Ragaie, Mahmoud A. El Hassab, Radwan El-Haggar, Wagdy M. Eldehna, Sara T. Al-Rashood, Shaimaa Mosallam
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1100-1111 (2022)
The current investigation aimed for loading fenticonazole nitrate (FTN), an antifungal agent with low aqueous solubility, into trans-novasomes (TNs) for management of tinea corporis topically. TNs contain Brij® as an edge activator besides the compo
Externí odkaz:
https://doaj.org/article/e6102fc0e22f40ae9d37379fc90ed96b
Autor:
Ibrahim H. Eissa, Radwan El-Haggar, Mohammed A. Dahab, Marwa F. Ahmed, Hazem A. Mahdy, Reem I. Alsantali, Alaa Elwan, Nicolas Masurier, Samar S. Fatahala
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1587-1599 (2022)
A novel series of 2-thioacetamide linked benzoxazole-benzamide conjugates 1–15 was designed as potential inhibitors of the vascular endothelial growth factor receptor-2 (VEGFR-2). The prepared compounds were evaluated for their potential antitumor
Externí odkaz:
https://doaj.org/article/df00a10607564622a1dbea3897e95ec3
Autor:
Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Tarfah Al-Warhi, Sara T. Al-Rashood, Amal Alharbi, Rezk R. Ayyad, Khayal Al-Khayal, Maha Abdulla, Hatem A. Abdel-Aziz, Rehan Ahmad, Radwan El-Haggar
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 320-329 (2021)
Mitochondrial anti-apoptotic Bcl2 and BclxL proteins, are overexpressed in multiple tumour types, and has been involved in the progression and survival of malignant cells. Therefore, inhibition of such proteins has become a validated and attractive t
Externí odkaz:
https://doaj.org/article/ae0ff9bf7af7424389e31b9650cd019c
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 308-319 (2021)
New piperazine–chalcone hybrids and related pyrazoline derivatives have been designed and synthesised as potential vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. The National Cancer Institute (NCI) has selected six compounds to
Externí odkaz:
https://doaj.org/article/f11a2870b33a44549e4693c85b2c8544
Autor:
Wagdy M. Eldehna, Rofaida Salem, Zainab M. Elsayed, Tarfah Al-Warhi, Hamada R. Knany, Rezk R. Ayyad, Thamer Bin Traiki, Maha-Hamadien Abdulla, Rehan Ahmad, Hatem A. Abdel-Aziz, Radwan El-Haggar
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1423-1434 (2021)
In the current work, a new set of carbohydrazide linked benzofuran-isatin conjugates (5a–e and 7a–i) was designed and synthesised. The anticancer activity for compounds (5b–d, 7a, 7b, 7d and 7g) was measured against NCI-55 human cancer cell lin
Externí odkaz:
https://doaj.org/article/3772b97f90654613a38cd0678b5d84ab
Autor:
Radwan El-Haggar, Reem I. Al-Wabli
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 5374-5391 (2015)
Coumarin and their derivatives have drawn much attention in the pharmacological and pharmaceutical fields due to their broad range and diverse biological activities. In the present work, starting from the 6-amino-7-hydroxy-4-methyl-2H-chromen-2-one,
Externí odkaz:
https://doaj.org/article/4ab2637f3ea142e0b64f6b9efb4a3c1f
Autor:
Amal H Ahmed, Samah Shabana, Radwan El Haggar, Roula Bayram, Asmaa S Abd Elkarim, Mohamed Fouad Shalaby, Alaa Khedr, Abdelbaset M. Elgamal
Publikováno v:
Pharmacognosy Journal. 13:1366-1376
Autor:
Rofaida Salem, Maha-Hamadien Abdulla, Zainab M. Elsayed, Thamer Bin Traiki, Rezk R. Ayyad, Rehan Ahmad, Tarfah Al-Warhi, Wagdy M. Eldehna, Hamada R. Knany, Radwan El-Haggar, Hatem A. Abdel-Aziz
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1423-1434 (2021)
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1423-1434 (2021)
In the current work, a new set of carbohydrazide linked benzofuran-isatin conjugates (5a–e and 7a–i) was designed and synthesised. The anticancer activity for compounds (5b–d, 7a, 7b, 7d and 7g) was measured against NCI-55 human cancer cell lin
Autor:
Radwan El-Haggar, Wagdy M. Eldehna, Amal Alharbi, Mahmoud F. Abo-Ashour, Hatem A. Abdel-Aziz, Maha Abdulla, Sara T. Al-Rashood, Tarfah Al-Warhi, Rehan Ahmad, Khayal Al-Khayal, Rezk R. Ayyad
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 320-329 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Mitochondrial anti-apoptotic Bcl2 and BclxL proteins, are overexpressed in multiple tumour types, and has been involved in the progression and survival of malignant cells. Therefore, inhibition of such proteins has become a validated and attractive t