Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Radwan Abu-Issa"'
Publikováno v:
Reproductive Biology. 20:88-96
Small VCP-interacting protein (SVIP) is a 9-kDa protein that is composed of 76 amino acids, and it plays a role in the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Recent studies have shown that SVIP is an androgen-responsive
Publikováno v:
Expert Systems with Applications. 156:113435
The concept of clustering is to separate clusters based on the similarity which is greater within cluster than among clusters. The similarity consists of two principles, namely, connectivity and cohesion. However, in partitional clustering, while som
Autor:
Radwan Abu-Issa
Publikováno v:
The Anatomical Record. 297:175-182
In chick and mouse, heart fields undergo dynamic morphological spatiotemporal changes during heart tube formation. Here, the dynamic change in spatial polarity of such fields is discussed and a new perspective on the heart fields is proposed. The hea
Publikováno v:
Developmental Dynamics. 236:684-695
The proepicardium (PE) is an embryonic progenitor cell population that delivers the epicardium, the majority of the cardiac interstitium, and the coronary vasculature. In the present study, we compared PE development in mouse and chick embryos. In th
Autor:
Erik N. Meyers, Yu-Ping Yang, Robert J. Schwartz, Roger M. Ilagan, Radwan Abu-Issa, Doris Brown, John Klingensmith, Kai Jiao
Publikováno v:
Development. 133:2435-2445
In the mouse embryo, the splanchnic mesodermal cells of the anterior heart field (AHF) migrate from the pharynx to contribute to the early myocardium of the outflow tract (OT) and right ventricle (RV). Recent studies have attempted to distinguish the
Autor:
Radwan Abu-Issa
Publikováno v:
Biochemical and biophysical research communications. 456(4)
Rac1, a member of the Rho subfamily of small GTPases, is involved in morphogenesis and differentiation of many cell types. Here we define a role of Rac1 in cardiac development by specifically deleting Rac1 in the pre-cardiac mesoderm using the Nkx2.5
Autor:
Erik N. Meyers, Ryan M. Anderson, Ken Ichi Yamamura, Radwan Abu-Issa, I. Washington Smoak, John Klingensmith, Noah A. Byrd, J. Morris, Matthew M. Goddeeris
Publikováno v:
Developmental Biology. 283(2):357-372
The Hedgehog signaling pathway is critical for a significant number of developmental patterning events. In this study, we focus on the defects in pharyngeal arch and cardiovascular patterning present in Sonic hedgehog (Shh) null mouse embryos. Our da
Autor:
Karen L. Waldo, Harriett A. Stadt, Donna Kumiski, Marzena Zdanowicz, Margaret L. Kirby, Mary R. Hutson, Radwan Abu-Issa, Cary C Ward
Publikováno v:
Developmental Biology. 281(1):78-90
The arterial pole of the heart is the region where the ventricular myocardium continues as the vascular smooth muscle tunics of the aorta and pulmonary trunk. It has been shown that the arterial pole myocardium derives from the secondary heart field
Publikováno v:
Developmental Biology. 272:281-285
Publikováno v:
Blood
About 80% of all cases of Fanconi anemia (FA) can be accounted for by complementation groups A and C. To understand the relationship between these groups, we analyzed the expression pattern of the mouse FA group-A gene (Fanca) during embryogenesis an