Cytotoxicity, nitric oxide and acetylcholinesterase inhibitory activity of three limonoids isolated from Trichilia welwitschii (Meliaceae)

Autor: Jean P. Dzoyem, Armelle T. Tsamo, Raduis Melong, Pierre Mkounga, Augustin E. Nkengfack, Lyndy J. McGaw, Jacobus N. Eloff

Publikováno v: Biological Research, Vol 48, Iss 0, Pp 1-6 (2015)

BACKGROUND: Limonoids are highly oxygenated compounds with a prototypical structure. Their occurrence in the plant kingdom is mainly confined to plant families of Meliaceae and Rutaceae. Owing to their wide range of pharmacological and therapeutic pr

Externí odkaz: https://doaj.org/article/5497d1a39ba741dd8da2456eb105eab4

New cytotoxic obacunone-type limonoid and others constituents from the stem bark of Carapa procera DC (Meliaceae)

Autor: Uwe Beifuss, Christian G. Bochet, Pierre Carolle Tamokoue Kengne, Gilbert D W F Kapche, Eric Allémann, Raduis Melong, Florence Delie, Jean Paul Dzoyem, Angelbert Awantu Fusi

Publikováno v: Natural Product Research. 36:2783-2790

The phytochemical study of the CH2Cl2- MeOH (1:1, v/v) extract of the stem bark of Carapa procera DC (Meliaceae) led to the isolation and characterisation of a new natural limonoid 7β-obacunol (6),...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13b94c6d7aa74688bf2b7f3fb22be1a0
https://doi.org/10.1080/14786419.2021.1927024

New antimicrobial cyclolignan and others constituents from the leaves of Scyphocephalium mannii (Benth. & Hook.f.) Warb

Autor: Dieu Ne Dort Nganteng, Raduis Melong, Timoleon Maffo, Roland T. Tchuenguem, Aurelien Crochet, Jean Paul Dzoyem, Pascal Wafo, Christian G. Bochet, Bonaventure Tchaleu Ngadjui

Chemical investigation of the MeOH extract of the leaves of Scyphocephalium mannii (Benth. & Hook.f.) Warb. (Myristicaceae) led to the isolation and characterization of one new metabolite (+)-(7’S, 8S, 8’S)-4,4’-dihydroxy-3,3’,5,5’-tetramet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a3c778d0d816ca6dfc966074272513f

Bioguided identification of pentacyclic triterpenoids as anti-inflammatory bioactive constituents of Ocimum gratissimum extract

Autor: Pascal Wafo, Eric Allémann, Raduis Melong, Dieu Ne Dort Nganteng, Bonaventure T. Ngadjui, Florence Delie, Jean Paul Dzoyem

Publikováno v: Journal of Ethnopharmacology, Vol. 268 (2021) P. 113637

Ethnopharmacological relevance Ocimum gratissimum is a plant spice widely used in African traditional medicine to treat pain-related conditions. However, the anti-inflammatory mechanisms underlying this activity and the main active ingredients in O.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6075cbfad3539327a136d6c3934c61
https://pubmed.ncbi.nlm.nih.gov/33264661

Cytotoxicity, antioxidant and antibacterial activity of four compounds produced by an endophytic fungus Epicoccum nigrum associated with Entada abyssinica

Autor: Bonaventure T. Ngadjui, Jacobus Nicolaas Eloff, Jean Paul Dzoyem, Armelle Tontsa Tsamo, Raduis Melong, Deccaux G.W.F. Kapche, Lyndy Joy McGaw, Timoleon Maffo

Publikováno v: Revista Brasileira de Farmacognosia, Vol 27, Iss 2, Pp 251-253
Revista Brasileira de Farmacognosia, Volume: 27, Issue: 2, Pages: 251-253, Published: APR 2017
Revista Brasileira de Farmacognosia, Vol 27, Iss 2, Pp 251-253 (2017)

Four compounds including beauvericin, parahydroxybenzaldehyde, indole-3-carboxylic acid and quinizarin were isolated from endophytic fungus Epicoccum nigrum and their cytotoxicity, antibacterial and antioxidant activity were evaluated. Beauvericin ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0030c781c737e2e5b1b1bb9f0cefe9