Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

Autor: Eric T. Miller, Sungyong You, Radu M. Cadaneanu, Minhyung Kim, Junhee Yoon, Sandy T. Liu, Xinmin Li, Lorna Kwan, Jennelle Hodge, Michael J. Quist, Catherine S. Grasso, Michael S. Lewis, Beatrice S. Knudsen, Michael R. Freeman, Isla P. Garraway

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-15 (2020)

Abstract Background Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linke

Externí odkaz: https://doaj.org/article/5aa779b2ab7b411bb44bb52788febd77

Epcam, CD44, and CD49f distinguish sphere-forming human prostate basal cells from a subpopulation with predominant tubule initiation capability.

Autor: Changyong Guo, Haibo Liu, Bao-Hui Zhang, Radu M Cadaneanu, Aqila M Mayle, Isla P Garraway

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34219 (2012)

BackgroundHuman prostate basal cells expressing alpha-6 integrin (CD49f(Hi)) and/or CD44 form prostaspheres in vitro. This functional trait is often correlated with stem/progenitor (S/P) activity, including the ability to self-renew and induce differ

Externí odkaz: https://doaj.org/article/70e32c3fcf324e7f9be8078ed8d41c10

Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

Autor: Xin-Min Li, Colette Galet, Tristan Grogan, Baohui Zhang, Matthew Rettig, Beatrice S. Knudsen, Stephen J. Freedland, Kevin Lai, Isla P. Garraway, Sandy T. Liu, William J. Aronson, Lihong Huo, Radu M. Cadaneanu, Michael S. Lewis, David Elashoff

Publikováno v: Liu, S; Cadaneanu, RM; Zhang, B; Huo, L; Lai, K; Li, X; et al.(2016). Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone. PLOS ONE, 11(10), e0163232. doi: 10.1371/journal.pone.0163232. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5pk8p165
PloS one, vol 11, iss 10
PLoS ONE, Vol 11, Iss 10, p e0163232 (2016)
PLoS ONE

Author(s): Liu, Sandy; Cadaneanu, Radu M; Zhang, Baohui; Huo, Lihong; Lai, Kevin; Li, Xinmin; Galet, Colette; Grogan, Tristan R; Elashoff, David; Freedland, Stephen J; Rettig, Matthew; Aronson, William J; Knudsen, Beatrice S; Lewis, Michael S; Garraw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d3ba5df42aa0d44132ce6f0c1b5b77
http://www.escholarship.org/uc/item/5pk8p165

Clonal diversity revealed by morphoproteomic and copy number profiles of single prostate cancer cells at diagnosis.

Autor: Paymaneh D Malihi, Michael Morikado, Lisa Welter, Sandy T Liu, Eric T Miller, Radu M Cadaneanu, Beatrice S Knudsen, Michael S Lewis, Anders Carlsson, Carmen Ruiz Velasco, Anand Kolatkar, Mariam Rodriguez-Lee, Isla P Garraway, James Hicks, Peter Kuhn

Publikováno v: Convergent Science Physical Oncology; Mar2018, Vol. 4 Issue 1, p1-1, 1p