Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Radu Aricescu, A."'
Autor:
Nonaka, Hiroshi, Mino, Takeharu, Sakamoto, Seiji, Oh, Jae Hoon, Watanabe, Yu, Ishikawa, Mamoru, Tsushima, Akihiro, Amaike, Kazuma, Kiyonaka, Shigeki, Tamura, Tomonori, Radu Aricescu, A., Kakegawa, Wataru, Miura, Eriko, Yuzaki, Michisuke, Hamachi, Itaru
Publikováno v:
In Chem 9 February 2023 9(2):523-540
Autor:
Hiroshi Nonaka, Takeharu Mino, Seiji Sakamoto, Jae Hoon Oh, Yu Watanabe, Mamoru Ishikawa, Akihiro Tsushima, Kazuma Amaike, Shigeki Kiyonaka, Tomonori Tamura, A. Radu Aricescu, Wataru Kakegawa, Eriko Miura, Michisuke Yuzaki, Itaru Hamachi
Publikováno v:
Chem. 9(2):523-540
Various small molecules have been used as functional probes for tissue imaging in medical diagnosis and pharmaceutical drugs for disease treatment. The spatial distribution, target selectivity, and diffusion/excretion kinetics of small molecules in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d25746fbc9746c96a025559845a21c9
http://hdl.handle.net/2433/279237
http://hdl.handle.net/2433/279237
Autor:
Nicolas Altemose, Nudrat Noor, Emmanuelle Bitoun, Afidalina Tumian, Michael Imbeault, J Ross Chapman, A Radu Aricescu, Simon R Myers
Publikováno v:
eLife, Vol 6 (2017)
PRDM9 binding localizes almost all meiotic recombination sites in humans and mice. However, most PRDM9-bound loci do not become recombination hotspots. To explore factors that affect binding and subsequent recombination outcomes, we mapped human PRDM
Externí odkaz:
https://doaj.org/article/646223caf7b14c82b8a670cb7ca40d0e
Autor:
Ali H. Shaib, Abed Alrahman Chouaib, Rajdeep Chowdhury, Daniel Mihaylov, Chi Zhang, Vanessa Imani, Svilen Veselinov Georgiev, Nikolaos Mougios, Mehar Monga, Sofiia Reshetniak, Tiago Mimoso, Han Chen, Parisa Fatehbasharzad, Dagmar Crzan, Kim-Ann Saal, Nadia Alawar, Janna Eilts, Jinyoung Kang, Luis Alvarez, Claudia Trenkwalder, Brit Mollenhauer, Tiago F. Outeiro, Sarah Köster, Julia Preobraschenski, Ute Becherer, Tobias Moser, Edward S. Boyden, A Radu Aricescu, Markus Sauer, Felipe Opazo, Silvio O. Rizzoli
Fluorescence imaging is one of the most versatile and widely-used tools in biology1. Although techniques to overcome the diffraction barrier were introduced more than two decades ago, and the nominal attainable resolution kept improving2, 3, fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40997f23ed2c132edc6729dde72197e
https://doi.org/10.1101/2022.08.03.502284
https://doi.org/10.1101/2022.08.03.502284
Autor:
Andrija Sente, Rooma Desai, Katerina Naydenova, Tomas Malinauskas, Youssef Jounaidi, Jonas Miehling, Xiaojuan Zhou, Simonas Masiulis, Steven W. Hardwick, Dimitri Y. Chirgadze, Keith W. Miller, A. Radu Aricescu
Publikováno v:
Nature
Type-A γ-aminobutyric acid receptors (GABA(A)Rs) are pentameric ligand-gated chloride channels that mediate fast inhibitory signalling in neural circuits( 1,2 ) and are modulated by essential medicines including general anaesthetics and benzodiazepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f928e59bd5199c06fca89677a54a4c
https://europepmc.org/articles/PMC7612593/
https://europepmc.org/articles/PMC7612593/
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 1, p e1004664 (2016)
The expression of long-term depression (LTD) in cerebellar Purkinje cells results from the internalisation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs) from the postsynaptic membrane. This process is regulated by a comp
Externí odkaz:
https://doaj.org/article/9540cda377a54c908e7d0b782b105b2b
Autor:
Peter Tiemeijer, Abhay Kotecha, Erwin de Jong, Takanori Nakane, Dimitri Y. Chirgadze, D. Karia, Steven W. Hardwick, Andrija Sente, Maarten Bischoff, Lina Malinauskaite, Jamie McCormack, Garib N. Murshudov, S. Masiulis, A. Radu Aricescu, Patricia M. G. E. Brown, Tomasz Uchański, Jonas Miehling, Sjors H.W. Scheres, Lingbo Yu, Ioana T. Grigoras, Jeroen Keizer, Evgeniya V. Pechnikova, Greg McMullan, Tomas Malinauskas
Publikováno v:
Nature
The three-dimensional positions of atoms in protein molecules define their structure and the roles they perform in biological processes. The more precisely atomic coordinates are determined, the more chemical information can be derived and the more m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c844e01171bd62488ea55ff1e98d24a
https://doi.org/10.1038/s41586-020-2829-0
https://doi.org/10.1038/s41586-020-2829-0
Autor:
Hiroshi Nonaka, Takeharu Mino, Seiji Sakamoto, Jae Hoon Oh, Yu Watanabe, Mamoru Ishikawa, Akihiro Tsushima, Kazuma Amaike, Shigeki Kiyonaka, Tomonori Tamura, A. Radu Aricescu, Wataru Kakegawa, Eriko Miura, Michisuke Yuzaki, Itaru Hamachi
Various small molecules have been used as functional probes for tissue imaging in medical diagnosis and pharmaceutical drugs for disease treatment. The spatial distribution, target selectivity, and diffusion/extrusion kinetics of small molecules in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1daf6261126f665a6fbebbf32f2efea
https://doi.org/10.1101/2021.12.21.473647
https://doi.org/10.1101/2021.12.21.473647
Autor:
Jordan J. Clark, Parul Sharma, Anja Kipar, Andrew Owen, Jan Löwe, Marina Vaysburd, James P. Stewart, Veronica T. Chang, Leo Kiss, Julian A. Hiscox, Anna Albecka, A. Radu Aricescu, Andres Gonzalez Llamazares, Ralf Salzer, Leo C. James
Publikováno v:
FEBS LETTERS
Febs Letters
Febs Letters
The COVID‐19 pandemic, caused by the SARS‐CoV‐2 coronavirus, has triggered a worldwide health emergency. Here, we show that ferritin‐like Dps from hyperthermophilic Sulfolobus islandicus, covalently coupled with SARS‐CoV‐2 antigens via th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046ee871cbb40186bc07b83f30a70c62
https://www.repository.cam.ac.uk/handle/1810/327182
https://www.repository.cam.ac.uk/handle/1810/327182