Decreased expression of TSLP in labial salivary glands of patients with primary Sjögren’s syndrome is associated with local- and systemic disease parameters

Autor: Hillen Maarten R, Bikker Angela, Kruize Aike A, Wenting-van Wijk Marion, Lafeber Floris PJG, Hack C, Radstake Timothy RDJ, van Roon Joel AG

Publikováno v: Journal of Translational Medicine, Vol 10, Iss Suppl 3, p P36 (2012)

Externí odkaz: https://doaj.org/article/bcca35cddfcf4367b03c3ee446e9bedf

Macrophage dysfunction in Psoriatic Arthritis

Autor: Wenink Mark H, Santegoets Kim CM, van Bon Lenny, Butcher John, van den Berg Wim B, van Riel Piet LCM, McInnes Iain B, Radstake Timothy RDJ

Publikováno v: Journal of Translational Medicine, Vol 9, Iss Suppl 2, p P59 (2011)

Externí odkaz: https://doaj.org/article/3ba8c7056a434651b802714543d23e56

Novel insights in the regulation of CCL18 secretion by monocytes and dendritic cells via cytokines, Toll-like receptors and rheumatoid synovial fluid

Autor: Schreurs B Willem, Roelofs Mieke F, le Blanc Linda MP, van der Voort Robbert, van Lieshout Antoine WT, van Riel Piet LCM, Adema Gosse J, Radstake Timothy RDJ

Publikováno v: BMC Immunology, Vol 7, Iss 1, p 23 (2006)

Abstract Background The T cell attracting chemokine CCL18 is produced by antigen presenting cells and a role for CCL18 has been suggested in the pathogenesis of a variety of diseases. Rheumatoid arthritis (RA) is one of these conditions, in which abu

Externí odkaz: https://doaj.org/article/8458179723084b34b9f695f2a9a70002

Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes

Autor: Acosta-Herrera, Marialbert, Kerick, Martin, Lopéz-Isac, Elena, Assassi, Shervin, Beretta, Lorenzo, Simeón-Aznar, Carmen Pilar, Ortego-Centeno, Norberto, International SSc Group, Proudman, Susanna M, Australian Scleroderma Interest Group (ASIG), Hunzelmann, Nicolas, Moroncini, Gianluca, de Vries-Bouwstra, Jeska K, Orozco, Gisela, Barton, Anne, Herrick, Ariane L, Terao, Chikashi, Allanore, Yannick, Brown, Matthew A, Radstake, Timothy Rdj, Fonseca, Carmen, Denton, Christopher P, Mayes, Maureen D, Martin, Javier

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 80(8), 1040-1047. BMJ PUBLISHING GROUP
Ann Rheum Dis . 2021 Apr 1;80(8):1040-1047
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Scientia

Objective The greatest genetic effect reported for systemic sclerosis (SSc) lies in the major histocompatibility complex (MHC) locus. Leveraging the largest SSc genome-wide association study, we aimed to fine-map this region to identify novel human l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aa3b23b3a7ed7d024352e8903f1b81
https://hdl.handle.net/10668/17969

Integration of immunome with disease gene network reveals pleiotropy and novel drug repurposing targets

Autor: Devaprasad, Abhinandan, Radstake, Timothy RDJ, Pandit, Aridaman

Immune system is crucial for the development and progression of immune-mediated and non-immune mediated complex diseases. Studies have shown that multiple complex diseases are associated with several immunologically relevant genes. Despite such growi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::c5232d3d9febf8d097cd3f2ff7534332