Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies

Autor: Lopez-Isac, E., Martin, J.E., Assassi, S., Simeon, C.P., Carreira, P., Ortego-Centeno, N., Freire, M., Beltran, E., Narvaez, J., Alegre-Sancho, J.J., Fernandez-Gutierrez, B., Balsa, A., Ortiz, A.M., Gonzalez-Gay, M.A., Beretta, L., Santaniello, A., Bellocchi, C., Lunardi, C., Moroncini, G., Gabrielli, A., Witte, T. de, Hunzelmann, N., Distler, J.H., Riekemasten, G., Mil, A.H.V. van der Helm-va, Vries-Bouwstra, J. de, Magro-Checa, C., Voskuyl, A.E., Vonk, M.C., Molberg, O., Merriman, T., Hesselstrand, R., Nordin, A., Padyukov, L., Herrick, A., Eyre, S., Koeleman, B.P.C., Denton, C.P., Fonseca, C., Radstake, T.R., Worthington, J., Mayes, M.D., Martin, J.

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
López-Isac, E, Martin, J-E, Assassi, S, Simeon, C P, Carreira, P, Ortego-Centeno, N, Freire, M, Beltran, E, Narváez, J, Alegre-Sancho, J J, Spanish Scleroderma Group, Benjamin, F-G, Balsa, A, Ortiz, A M, Gonzalez-Gay, M A, Beretta, L, Santaniello, A, Bellocchi, C, Lunardi, C, Moroncini, G, Gabrielli, A, Witte, T, Hunzelmann, N, Distler, J H W, Riekemasten, G, Van Der Helm-Van Mil, A, de Vries-Bouwstra, J, Magro-Checa, C, Vonk, M C, Molberg, Ø, Merriman, T, Hesselstrand, R, Nordin, A, Padyukov, L, Herrick, A, Eyre, S, Koeleman, B P C, Denton, C P, Fonseca, C, Radstake, T R D J, Worthington, J, Mayes, M D & Martin, J 2016, ' Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies ', Arthritis and Rheumatology, vol. 68, no. 9, pp. 2338-44 . https://doi.org/10.1002/art.39730
Arthritis & Rheumatology, 68, 2338-44
Arthritis & Rheumatology, 68, 9, pp. 2338-44

Contains fulltext : 172048.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Systemic sclerosis (SSc) and rheumatoid arthritis (RA) are autoimmune diseases that have similar clinical and immunologic characteristics. To date, several shared SSc-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::601df0fb6dc21a620bb317b1832485de
https://hdl.handle.net/2066/172048

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

Autor: Nakayama, A., Nakaoka, H., Yamamoto, K., Sakiyama, M., Shaukat, A., Toyoda, Y., Okada, Y., Kamatani, Y., Nakamura, T., Takada, T., Inoue, K., Yasujima, T., Yuasa, H., Shirahama, Y., Nakashima, H., Shimizu, S., Higashino, T., Kawamura, Y., Ogata, H., Kawaguchi, M., Ohkawa, Y., Danjoh, I., Tokumasu, A., Ooyama, K., Ito, T., Kondo, T., Wakai, K., Stiburkova, B., Pavelka, K., Stamp, L.K., Dalbeth, N., Sakurai, Y., Suzuki, H, Hosoyamada, M., Fujimori, S., Yokoo, T., Hosoya, T., Inoue, I., Takahashi, A., Kubo, M., Ooyama, H., Shimizu, T., Ichida, K., Shinomiya, N., Merriman, T.R., Matsuo, H., Andres, M, Joosten, L.A., Janssen, M.C.H., Jansen, T.L., Liote, F., Radstake, T.R., Riches, P.L., So, A., Tauches, A.K.

Publikováno v: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 76, 5, pp. 869-877
Annals of the Rheumatic Diseases, 76, 869-877

ObjectiveA genome-wide association study (GWAS) of gout and its subtypes was performed to identify novel gout loci, including those that are subtype-specific.MethodsPutative causal association signals from a GWAS of 945 clinically defined gout cases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2a5dd31d3aff39767527642a4d8828
https://pubmed.ncbi.nlm.nih.gov/27899376

Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression

Autor: Broen, J.C., Dieude, P., Vonk, M.C., Beretta, L., Carmona, F.D., Herrick, A., Worthington, J., Hunzelmann, N., Riemekasten, G., Kiener, H., Scorza, R., Simeon, C.P., Fonollosa, V., Spanish Systemic Sclerosis, G., Carreira, P., Ortego-Centeno, N., Gonzalez-Gay, M.A., Airo, P., Coenen, M.J., Tsang, K., Aliprantis, A.O., Martin, J., Allanore, Y., Radstake, T.R.

Publikováno v: The Journal of Rheumatology, 39, 1, pp. 112-8
The Journal of Rheumatology, 39, 112-8

Objective.Polymorphisms in the genes encoding interleukin 4 (IL4), interleukin 13 (IL13), and their corresponding receptors have been associated with multiple immune-mediated diseases. Our aim was to validate these previous observations in patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37023cd8a9fbc07d3546066186efa0a6
https://hdl.handle.net/2066/109087

Identification of small heat-shock protein B8 (HSP22) as a novel Toll-like receptor 4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis

Autor: Roelofs, M.F., Boelens, W.C., Joosten, L., Berg, W.B. van den, Radstake, T.R.

Publikováno v: Annals of the Rheumatic Diseases, 65, A15-A15
Annals of the Rheumatic Diseases, 65, S1, pp. A15-A15

Contains fulltext : 289272.pdf (Publisher’s version ) (Closed access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::657e77fb1653c992fa5aeba01223f9dd
http://hdl.handle.net/2066/289272

Can psychological interventions alter the physiological stress response of patients with rheumatoid arthritis?

Autor: Brouwer, S.J.M. de, Kraaimaat, F.W., Sweep, C.G.J., Donders, A.R.T., Eijsbouts, A.M.M., Radstake, T.R., Riel, P.L. van, Evers, A.W.M.

Publikováno v: Rheumatology, 50, ii28-ii28
Rheumatology, 50, 2, pp. ii28-ii28

Contains fulltext : 97698.pdf (Publisher’s version ) (Closed access)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f7ea4b60c0d3bf5007c6a56f75f806f8
https://hdl.handle.net/2066/97698