Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Radostina Bachmaier"'
Autor:
Jozef Ban, Christopher Poremba, Laura Spahn, Karl-Ludwig Schaefer, Heinrich Kovar, Radostina Bachmaier, Dave N. T. Aryee, Michael Kreppel, Christine Siligan
Publikováno v:
Oncogene. 24:2512-2524
In all, 85% of Ewing's sarcoma family tumors (ESFT), a neoplasm of unknown histogenesis, express EWS-FLI1 transcription factor gene fusions. To characterize direct target genes avoiding artificial model systems, we cloned genomic DNA from ESFT chroma
Publikováno v:
Virology. 332(2):563-577
Phosphorylation of Tobacco mosaic virus movement protein (TMV-MP) at three carboxyterminal Ser/Thr sites negatively regulates TMV-MP gating function and viral spread in Nicotiana tabacum but not in Nicotiana benthamiana, indicating a host dependant i
Publikováno v:
Scopus-Elsevier
Cell-to-cell spread of tobacco mosaic virus (TMV) through plant intercellular connections, the plasmodesmata, is mediated by a specialized viral movement protein (MP). In vivo studies using transgenic tobacco plants showed that MP is phosphorylated a
Autor:
Dave N. T. Aryee, Gunhild Jug, Kevin A.W. Lee, Radostina Bachmaier, Heinrich Kovar, Maximilian Kauer, Michael Kreppel
The oncogene EWS-FLI1 encodes a chimeric transcription factor expressed in Ewing's sarcoma family tumors (ESFTs). EWS-FLI1 target gene expression is thought to drive ESFT pathogenesis and, therefore, inhibition of EWS-FLI1 activity holds high therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd4aecbd8fea62e2a9f9fd9369029a4
https://europepmc.org/articles/PMC4959569/
https://europepmc.org/articles/PMC4959569/
Autor:
Heinrich Kovar, Jozef Ban, Heimo Breiteneder, Jeffrey A. Toretsky, Karin Muehlbacher, Michael Kreppel, Dave N. T. Aryee, Radostina Bachmaier, Aykut Üren, Stefan Wagner
Publikováno v:
Cancer research. 66(20)
The chimeric protein EWS-FLI1, arising from chromosomal translocation in Ewing's sarcoma family tumors (ESFT), acts as an aberrant tumorigenic transcription factor. The transforming activity of EWS-FLI1 minimally requires an ETS DNA binding domain an
Autor:
Dave N. T. Aryee, Christine Siligan, Johannes A. Schmid, Radostina Bachmaier, Laura Spahn, Heinrich Kovar
Publikováno v:
Oncogene. 22(44)
In Ewing's sarcoma family tumors, the ets transcription factor gene FLI1 is rearranged with one EWS allele resulting in coexpression of germline EWS and chimeric EWS-FLI1 proteins. Here, we investigated the potential of germline EWS, FLI1 and EWS-FLI