Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Radoslav Savic"'
Autor:
Josep M. Llovet, Scott L. Friedman, Myron Schwartz, Vincenzo Mazzaferro, Jordi Bruix, Stephen C. Ward, Swan Thung, Jordi Barretina, Hung-Wen Tsai, Philippa Newell, Beatriz Minguez, Augusto Villanueva, Yujin Hoshida, Sara Toffanin, Laia Cabellos, Radoslav Savic, Clara Alsinet, Anja Lachenmayer
PDF file, 10.8MB, Supplementary Table 1: Clinical characteristics of human hepatocellular carcinoma samples. Supplementary Table 2: Clinical Characteristics of 5 public HCC datasets. Supplementary Table 3: Wnt-pathway mRNA list: 210 Wnt-related genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7bc1a4563b714df9e6c108a776a695
https://doi.org/10.1158/1078-0432.22444386.v1
https://doi.org/10.1158/1078-0432.22444386.v1
Autor:
Josep M. Llovet, Scott L. Friedman, Myron Schwartz, Vincenzo Mazzaferro, Jordi Bruix, Stephen C. Ward, Swan Thung, Jordi Barretina, Hung-Wen Tsai, Philippa Newell, Beatriz Minguez, Augusto Villanueva, Yujin Hoshida, Sara Toffanin, Laia Cabellos, Radoslav Savic, Clara Alsinet, Anja Lachenmayer
Purpose: Hepatocellular carcinoma (HCC) is a heterogeneous cancer with active Wnt signaling. Underlying biologic mechanisms remain unclear and no drug targeting this pathway has been approved to date. We aimed to characterize Wnt-pathway aberrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e6c6da9153f44eaadd81eed98dc49a7
https://doi.org/10.1158/1078-0432.c.6520146
https://doi.org/10.1158/1078-0432.c.6520146
Autor:
Lan Jin, Satish Govindaraj, Zongzhi Liu, Lei Ai, Mitchell Higashi, Tomi Jun, Kyeryoung Lee, Kalpana Raja, Xingmin Zhang, Minghao Li, Ediz Calay, Radoslav Savic, Krish Ghosh, Andrew Kasarskis, Qi Pan, William Oh, Gustavo Stolovitzky, Eric Schadt, Xiaoyan Wang
Publikováno v:
ISEE Conference Abstracts. 2022
Autor:
Kyeryoung Lee, David Cohn, Zongzhi Liu, Lei Ai, Hunki Paek, Lan Jin, Kalpana Raja, Minghao Li, Xingmin Zhang, Tomi Jun, Mitchell Higashi, William Oh, Ediz S. Calay, Radoslav Savic, Krish Ghosh, Andrew Kasarskis, Tommy Mullaney, Qi Pan, Eric Schadt, Xiaoyan Wang
Publikováno v:
Journal of Clinical Oncology. 40:e13563-e13563
e13563 Background: Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease with multiple phenotypes and endotypes and associated with lung cancer development. In this study, we analyzed the clinical features of COPD including various
Autor:
Gabriel E. Hoffman, Brian J. Eastwood, Ching He, Joel T. Dudley, David A. Evans, Eric E. Schadt, Kristen J. Brennand, Pamela Sklar, Radoslav Savic, Richard Farias, Benjamin Readhead, David A. Collier, Brigham J. Hartley
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
A lack of biologically relevant screening models hinders the discovery of better treatments for schizophrenia (SZ) and other neuropsychiatric disorders. Here we compare the transcriptional responses of 8 commonly used cancer cell lines (CCLs) directl
Autor:
Joel T. Dudley, Eric E. Schadt, Pamela Sklar, Gabriel E. Hoffman, David A. Evans, Richard Farias, Ching He, Benjamin Readhead, David A. Collier, Brigham J. Hartley, Radoslav Savic, Brian J. Eastwood, Kristen J. Brennand
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
A lack of biologically relevant screening models hinders the discovery of better treatments for schizophrenia (SZ) and other neuropsychiatric disorders. Here we compare the transcriptional responses of 8 commonly used cancer cell lines (CCLs) directl
Autor:
Radoslav Savić, Jialiang Yang, Simon Koplev, Mahru C. An, Priyanka L. Patel, Robert N. O’Brien, Brittany N. Dubose, Tetyana Dodatko, Eduard Rogatsky, Katyayani Sukhavasi, Raili Ermel, Arno Ruusalepp, Sander M. Houten, Jason C. Kovacic, Andrew F. Stewart, Christopher B. Yohn, Eric E. Schadt, Remi-Martin Laberge, Johan L.M. Björkegren, Zhidong Tu, Carmen Argmann
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113371- (2023)
Summary: Senescent cells are a major contributor to age-dependent cardiovascular tissue dysfunction, but knowledge of their in vivo cell markers and tissue context is lacking. To reveal tissue-relevant senescence biology, we integrate the transcripto
Externí odkaz:
https://doaj.org/article/1c20f6d542d54b86acc9526737df22b2
Autor:
Jordi Barretina, Beatriz Minguez, Hung Wen Tsai, Radoslav Savic, Clara Alsinet, Vincenzo Mazzaferro, Stephen C. Ward, Myron Schwartz, Anja Lachenmayer, Scott L. Friedman, Philippa Newell, Sara Toffanin, Swan N. Thung, Yujin Hoshida, Augusto Villanueva, Jordi Bruix, Josep M. Llovet, Laia Cabellos
Publikováno v:
Clinical Cancer Research. 18:4997-5007
Purpose: Hepatocellular carcinoma (HCC) is a heterogeneous cancer with active Wnt signaling. Underlying biologic mechanisms remain unclear and no drug targeting this pathway has been approved to date. We aimed to characterize Wnt-pathway aberrations
Autor:
Dusica Maysinger, Radoslav Savic
Publikováno v:
Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74815d5dc4d0af52f73076b2473eb49d
https://doi.org/10.1002/9781118856017.ch11
https://doi.org/10.1002/9781118856017.ch11
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e65620 (2013)
PLoS ONE, Vol 8, Iss 5, p e65620 (2013)
Background Hepatocellular carcinoma (HCC) is the most common form of liver cancer and the third leading cause of cancer death worldwide. The only approved systemic treatment for unresectable HCC is the oral kinase inhibitor, sorafenib. Recombinant hu