Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Radosław Podsiadły"'
Autor:
Karolina Pierzchała, Marlena Pięta, Monika Rola, Małgorzata Świerczyńska, Angelika Artelska, Karolina Dębowska, Radosław Podsiadły, Jakub Pięta, Jacek Zielonka, Adam Sikora, Andrzej Marcinek, Radosław Michalski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract MPO-derived oxidants including HOCl contribute to tissue damage and the initiation and propagation of inflammatory diseases. The search for small molecule inhibitors of myeloperoxidase, as molecular tools and potential drugs, requires the ap
Externí odkaz:
https://doaj.org/article/0d0c54d8360f4776869e515cc662ed47
Publikováno v:
Molecules, Vol 28, Iss 17, p 6299 (2023)
Hydrogen sulfide (H2S) is an important gasotransmitter, but only a few methods are available for real-time detection. Fluorescent probes are attractive tools for biological applications because of their high sensitivity, convenience, rapid implementa
Externí odkaz:
https://doaj.org/article/f08777b2171d47388185aca2bec79256
Publikováno v:
Molecules, Vol 28, Iss 16, p 5965 (2023)
Novel fluorescent probes based on 2(1H)-quinolone skeleton containing a malonate group (Q1–Q3) were synthesized and proposed for biothiols detection. Their chemical reactivity toward thiols was compared to the reactivity of derivative having a dicy
Externí odkaz:
https://doaj.org/article/f309231a08c541d488949608333e0903
Autor:
Małgorzata Świerczyńska, Daniel Słowiński, Radosław Michalski, Jarosław Romański, Radosław Podsiadły
Publikováno v:
Molecules, Vol 28, Iss 16, p 6055 (2023)
Hypochlorous acid (HOCl) has been implicated in numerous pathologies associated with an inflammatory component, but its selective and sensitive detection in biological settings remains a challenge. In this report, imaging of HOCl was realized with a
Externí odkaz:
https://doaj.org/article/7cb381c836fb4d23b71adbce12f452fa
Publikováno v:
Molecules, Vol 27, Iss 23, p 8305 (2022)
Hydrogen sulfide (H2S) and its bioderivatives analogs, such as L-cysteine (L-Cys) and glutathione (GSH), are ubiquitous biological thiols in the physiological and pathological processes of living systems. Their aberrant concentration levels are assoc
Externí odkaz:
https://doaj.org/article/8a3b54730b274d7ca7cd6ec1b631aa2e
Autor:
Daniel Swoboda, Jacek E. Nycz, Nataliya Karaush-Karmazin, Boris Minaev, Maria Książek, Joachim Kusz, Radosław Podsiadły
Publikováno v:
Molecules, Vol 27, Iss 21, p 7519 (2022)
Two unique structures were isolated from the phosphorylation reaction of 10H-phenothiazine. The 5,5-dimethyl-2-(10H-phenothiazin-10-yl)-1,3,2-dioxaphosphinane 2-oxide (2a) illustrates the product of N-phosphorylation of phenothiazine. Moreover, a pot
Externí odkaz:
https://doaj.org/article/684207660fcd4a56b4db90a6333a0c70
Autor:
Adam Sikora, Jacek Zielonka, Karolina Dębowska, Radosław Michalski, Renata Smulik-Izydorczyk, Jakub Pięta, Radosław Podsiadły, Angelika Artelska, Karolina Pierzchała, Balaraman Kalyanaraman
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Boronate-based molecular probes are emerging as one of the most effective tools for detection and quantitation of peroxynitrite and hydroperoxides. This review discusses the chemical reactivity of boronate compounds in the context of their use for de
Externí odkaz:
https://doaj.org/article/5ea21736d5f045d893e2d5e8b209a297
Autor:
Julia Modrzejewska, Marcin Szala, Aleksandra Grzelakowska, Małgorzata Zakłos-Szyda, Jacek Zielonka, Radosław Podsiadły
Publikováno v:
Molecules, Vol 26, Iss 19, p 5940 (2021)
Derivatives of coumarin, containing oxidant-sensitive boronate group, were recently developed for fluorescent detection of inflammatory oxidants. Here, we report the synthesis and the characterization of 3-(2-benzothiazolyl)-7-coumarin boronic acid p
Externí odkaz:
https://doaj.org/article/89a734b1c7b54c8d8a043c41db1e98c1
Publikováno v:
International Journal of Photoenergy, Vol 2012 (2012)
Novel photoinitiator systems working under visible radiation were studied. The photoredox pair constructed with dye derivatives of 12H-quinoxalino-[2,3-b][1,4]-benzothiazine (1–3) and 2,4,6-tris(trichloromethyl)-1,3,5-triazine (Tz) were found to be
Externí odkaz:
https://doaj.org/article/d787704bcf01454a9d4691f41ea475ed
Autor:
Aleksandra Grzelakowska, Julia Modrzejewska, Jolanta Kolińska, Marcin Szala, Monika Zielonka, Karolina Dębowska, Małgorzata Zakłos-Szyda, Adam Sikora, Jacek Zielonka, Radosław Podsiadły
Publikováno v:
Free Radical Biology and Medicine. 179:34-46
Peroxynitrite (ONOO