Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Radomír Nosál"'
Autor:
Marianna Lucová, Jan Šmidrkal, Juraj Harmatha, Katarína Drábiková, Viera Jančinová, Silvia Pažoureková, Radomír Nosál
Publikováno v:
Pharmacology. 97:138-145
Equol (7,4′-dihydroxy-isoflavan, or 4′,7-isoflavandiol) is a chroman derivative produced by intestinal bacteria in response to soy isoflavone intake in some, but not in all, humans. Equol shows strong anti-oxidant, anti-estrogenic, anti-cancerous
Publikováno v:
Life Sciences. 100:67-72
Aims The diverse physiological functions of histamine are mediated through distinct histamine receptors. In this study we investigated the role of H2R and H4R in the effects of histamine on the production of reactive oxygen species by phagocytes in w
Autor:
Frantisek Drafi, Silvester Ponist, Danica Mihalova, Radomír Nosál, T. Fedorova, Juraj Harmatha, Katarína Bauerová, Viera Kuncirova
Publikováno v:
Interdisciplinary Toxicology
Oxygen metabolism has an important role in the pathogenesis of rheumatoid arthritis. A certain correlation was observed between oxidative stress, arthritis and the immune system. Reactive oxygen species produced in the course of cellular oxidative ph
Autor:
Lucia Paulovičová, Ganesh Shimoga, Juraj Kronek, Dusan Chorvat, Viera Jančinová, Marcel Mikulec, Ema Paulovičová, Palem S. Reddy, Nadežda Petrenčíková, Zuzana Kroneková, Radomír Nosál
Publikováno v:
Macromolecular bioscience. 16(8)
Poly(2-alkenyl-2-oxazoline)s are promising functional polymers for a variety of biomedical applications, such as drug delivery systems, peptide conjugates, or gene delivery. In this study, poly(2-isopropenyl-2-oxazoline) (PIPOx) is prepared through f
Autor:
Viera Jančinová, Katarína Drábiková, Tomáš Perečko, Daniela Košt’álová, Katarína Bauerová, Radomír Nosál
Publikováno v:
European Journal of Pharmacology. 612:161-166
article i nfo Diferuloylmethane (curcumin) has been shown to act beneficially in arthritis, particularly through downregulated expression of proinflammatory cytokines and collagenase as well as through the modulated activities of T lymphocytes and ma
Autor:
Viera Jančinová, Peter Turcani, Tatiana Mačičková, Radomír Nosál, Katarína Drábiková, Jana Pečivová
Publikováno v:
Luminescence. 22:67-71
The chemiluminescence (CL) technique with luminol and isoluminol was used to characterize the effect of stobadine on reactive oxygen metabolites (ROM) generation in human whole blood and in isolated polymorphonuclear leukocytes (PMNL) stimulated with
Autor:
Lucia Račková, Nataša Mrvová, Jana Navarová, Marcela Kuniaková, Vladimir Knezl, Miroslav Veverka, Radomír Nosál
Publikováno v:
Free radical biologymedicine. 75
A number of studies have indicated that brain inflammation may deteriorate during normal aging and that neuroinflammation is amplified in age-related neurodegenerative diseases. A pivotal role in age-related neuroinflammatory pathologies is attribute
Autor:
Beatrice Arezzini, Danica Mihalova, Daniela Vecchio, Viera Kuncirova, Katarína Bauerová, Frantisek Drafi, Concetta Gardi, Alessandra Acquaviva, Radomír Nosál, Lydia Bezakova, Silvester Ponist
Oxidative stress (OS) is important in the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA) and its experimental model--adjuvant arthritis (AA). Antioxidants are scarcely studied in autoimmunity, and future analyses are needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a137f7acc8445ad55c9abfb9bdbf66d
http://hdl.handle.net/11365/49808
http://hdl.handle.net/11365/49808
Publikováno v:
Biomedical Papers. 149:389-392
Activation of neutrophils induces generation of reactive oxygen species and release of granule enzymes, which not only participate in the bactericidal mechanisms of these cells, but also in possible tissue damage. We studied the effect of carvedilol
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 65:55-64
Carvedilol inhibits luminol-enhanced chemiluminescence of reactive oxygen metabolites in vitro. In this study it was found that, in the cell-free system, carvedilol dose-dependently decreased chemiluminescence in the following ranking order of radica