Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Radomír Hrdina"'
Publikováno v:
Molecules, Vol 19, Iss 7, Pp 9606-9609 (2014)
We wish to offer some comments on the article by H. Liu et al. entitled “Evaluation of antioxidant and immunity activities of quercetin in isoproterenol-treated rats”, published in Molecules in 2012 [1]. [...]
Externí odkaz:
https://doaj.org/article/aa3deaaa60c84d7bb7070f59fde1714a
Publikováno v:
Acta Medica, Vol 48, Iss 3, Pp 127-135 (2005)
Iron is an essential element involved in many life-necessary processes. Interestingly, in mammals there is no active excretion mechanism for iron. Therefore iron kinetics has to be meticulously regulated. The most important step for regulation of iro
Externí odkaz:
https://doaj.org/article/1a1e5f77b63c436393cdde93a75a1b73
Publikováno v:
Acta Medica, Vol 48, Iss 2, Pp 67-73 (2005)
Endothelins are potent predominantly vasoconstricting agents that act as local autocrine and paracrine mediators. Endothelin-1 is the most potent and sustained vasoconstrictor and pressor substance yet identified. Abnormalities of the endothelin syst
Externí odkaz:
https://doaj.org/article/e6114750a1dc45e2b0ef522e39c826f7
Publikováno v:
Acta Medica, Vol 47, Iss 3, Pp 157-162 (2004)
Endothelins are endogenous vasoactive peptides that are considered among the most potent vasoconstrictor substances known. In addition to their vascular effects, endothelins and their receptors have been shown to be present in many organs and share p
Externí odkaz:
https://doaj.org/article/3055cf11953e4098ba76adad317e9a73
Autor:
Michaela Adamcová, Martin Štěrba, Ivona Klimtová, Tomáš Šimůnek, Radomír Hrdina, Vladimír Geršl, Přemysl Poňka
Publikováno v:
Acta Medica, Vol 46, Iss 4, Pp 171-174 (2003)
Both cardiac troponin T (cTnT) and cardiac troponin I (cTnI) are considered to be reliable biomarkers with sufficient sensitivity and specificity for cardiac injury in the majority of laboratory animals. The aim of our study was to compare the diagno
Externí odkaz:
https://doaj.org/article/60abc12410fc4255a2de72aabe65f890
Autor:
Ivona Klimtová, Tomáš Šimůnek, Yvona Mazurová, Jana Kaplanová, Martin Štěrba, Radomír Hrdina, Vladimír Geršl, Michaela Adamcová, Přemysl Poňka
Publikováno v:
Acta Medica, Vol 46, Iss 4, Pp 163-170 (2003)
Salicylaldehyde Isonicotinoyl Hydrazone (SIH) – a Pyridoxal Isonicotinoyl Hydrazone (PIH) analogue – is an effective iron chelator with antioxidant and antimalarial effects, as documented in numerous in vitro studies. However, no toxicological da
Externí odkaz:
https://doaj.org/article/5d7f21374a1f4a71a5ef14fcc1d36e6d
Autor:
Michaela Adamcová, Vladimír Geršl, Jarmila Macháčková, Radomír Hrdina, Ivona Klimtová, Tomáš Šimůnek, Jaroslava Vávrová, Josef Bukač
Publikováno v:
Acta Medica, Vol 45, Iss 1, Pp 29-32 (2002)
The aim of our study was to compare the diagnostic performance of cardiac troponin T (cTnT) and cardiac troponin I (cTnI) in three groups of rabbits: 1) control (saline 1 ml/kg i.v.); 2) daunorubicin (3 mg/kg i.v.); 3) daunorubicin (3 mg/kg i.v.) + d
Externí odkaz:
https://doaj.org/article/80199461503d40b8af0c77ccf4f7dfaf
Autor:
Radomír Hrdina, Vladimír Geršl, Ivona Klimtová, Tomáš Šimůnek, Yvona Mazurová, Jarmila Macháčková, Michaela Adamcová
Publikováno v:
Acta Medica, Vol 45, Iss 3, Pp 99-105 (2002)
A possible protective action of DMPS (a dithiol chelating agent) against chronic daunorubicin toxicity in rabbits in comparison with dexrazoxane was investigated. The rabbits were divided into five groups: control (saline, 1 ml/kg i.v.), daunorubicin
Externí odkaz:
https://doaj.org/article/f247b4fcceab4ee5b6f3e11f5be3ab93
Autor:
Radomír Hrdina, Vladimír Geršl, Ivona Klimtová, Tomáš Šimůnek, Jarmila Macháčková, Michaela Adamcová
Publikováno v:
Acta Medica, Vol 43, Iss 3, Pp 75-82 (2000)
Anthracycline antibiotics are among the most effective and widely used antineoplastic drugs. Their usefulness is limited by a cumulative dose-related cardiotoxicity, whose precise mechanisms are not clear as yet. The principal role is possibly exerte
Externí odkaz:
https://doaj.org/article/0e921a2dd83545d4bd2f3fa218f9bc79
Publikováno v:
Acta Medica, Vol 42, Iss 3, Pp 89-92 (1999)
The influence of repeated i.v. administration of dimethoxybenfluron (NO-1-B) (12 or 24 mg base/kg once weekly, 10 weeks) on biochemical and haematological parameters were studied in rabbits in vivo. No significant changes were mostly found in the ser
Externí odkaz:
https://doaj.org/article/a2061d59444a453f90fd2847d75a4bf3