Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Radmila Terentyeva"'
Autor:
Kelsey M. Pinckard, Elisa Félix-Soriano, Shanna Hamilton, Radmila Terentyeva, Lisa A. Baer, Katherine R. Wright, Drew Nassal, Joao Victor Esteves, Eaman Abay, Vikram K. Shettigar, Mark T. Ziolo, Thomas J. Hund, Loren E. Wold, Dmitry Terentyev, Kristin I. Stanford
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101914- (2024)
Objective: The intrauterine environment during pregnancy is a critical factor in the development of obesity, diabetes, and cardiovascular disease in offspring. Maternal exercise prevents the detrimental effects of a maternal high fat diet on the meta
Externí odkaz:
https://doaj.org/article/43233158c48a4f618c81e1532dc8152a
Autor:
Mikhail Tarasov, Heather L. Struckman, Yusuf Olgar, Alec Miller, Mustafa Demirtas, Vladimir Bogdanov, Radmila Terentyeva, Andrew M. Soltisz, Xiaolei Meng, Dennison Min, Galina Sakuta, Izabella Dunlap, Antonia D. Duran, Mark P. Foster, Jonathan P. Davis, Dmitry Terentyev, Sándor Györke, Rengasayee Veeraraghavan, Przemysław B. Radwański
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Calmodulin (CaM) plays critical roles in cardiomyocytes, regulating Na+ (NaV) and L-type Ca2+ channels (LTCCs). LTCC dysregulation by mutant CaMs has been implicated in action potential duration (APD) prolongation and arrhythmogenic long QT (LQT) syn
Externí odkaz:
https://doaj.org/article/81e38ae2959b485889b6727a408e1abd
Autor:
Shanna Hamilton, Radmila Terentyeva, Tae Yun Kim, Peter Bronk, Richard T. Clements, Jin O-Uchi, György Csordás, Bum-Rak Choi, Dmitry Terentyev
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
In a physiological setting, mitochondria increase oxidative phosphorylation during periods of stress to meet increased metabolic demand. This in part is mediated via enhanced mitochondrial Ca2+ uptake, an important regulator of cellular ATP homeostas
Externí odkaz:
https://doaj.org/article/afd9fd2a470d40ac8bbdb50a6b5dfb09
Autor:
Andriy E Belevych, Hsiang-Ting Ho, Radmila Terentyeva, Ingrid M Bonilla, Dmitry Terentyev, Cynthia A Carnes, Sandor Gyorke, George E Billman
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78414 (2013)
It has been proposed that dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) can reduce the risk of ventricular arrhythmias in post-MI patients. Abnormal Ca(2+) handling has been implicated in the genesis of post-MI ventricular arrhythmias. Ther
Externí odkaz:
https://doaj.org/article/bb28aef6fe6e43e6bb1b815ecbc9f852
Autor:
Andriy E Belevych, Sarah E Sansom, Radmila Terentyeva, Hsiang-Ting Ho, Yoshinori Nishijima, Mickey M Martin, Hitesh K Jindal, Jennifer A Rochira, Yukiko Kunitomo, Maha Abdellatif, Cynthia A Carnes, Terry S Elton, Sandor Györke, Dmitry Terentyev
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28324 (2011)
In heart failure (HF), arrhythmogenic spontaneous sarcoplasmic reticulum (SR) Ca(2+) release and afterdepolarizations in cardiac myocytes have been linked to abnormally high activity of ryanodine receptors (RyR2s) associated with enhanced phosphoryla
Externí odkaz:
https://doaj.org/article/82b72743a2f04eee91cbcfb491c230a0
Autor:
Ingrid M. Bonilla, Stephen Baine, Anastasia Pokrass, Juan Ignacio Elio Mariángelo, Anuradha Kalyanasundaram, Vladimir Bogdanov, Louisa Mezache, Galina Sakuta, Casey M. Beard, Andriy Belevych, Svetlana Tikunova, Radmila Terentyeva, Dmitry Terentyev, Jonathan Davis, Rengasayee Veeraraghavan, Cynthia A. Carnes, Sandor Györke
Publikováno v:
Journal of Applied Physiology. 134:1287-1299
Store-operated Ca2+ entry (SOCE) has been implicated in pathological cardiac hypertrophy; however, its role in physiological hypertrophy is unknown. Here we report that SOCE is also essential for physiological cardiac hypertrophy and functional adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860459041ef77caeee38662e60940451
https://doi.org/10.1152/japplphysiol.00363.2022
https://doi.org/10.1152/japplphysiol.00363.2022
Autor:
Richard T. Clements, Radmila Terentyeva, Shanna Hamilton, Paul M. L. Janssen, Karim Roder, Benjamin Y. Martin, Fruzsina Perger, Timothy Schneider, Zuzana Nichtova, Anindhya S. Das, Roland Veress, Beth S. Lee, Do-Gyoon Kim, Gideon Koren, Matthew S. Stratton, Gyorgy Csordas, Federica Accornero, Andriy E. Belevych, Sandor Gyorke, Dmitry Terentyev
Publikováno v:
Basic Research in Cardiology. 118
Calcium transfer into the mitochondrial matrix during sarcoplasmic reticulum (SR) Ca2+ release is essential to boost energy production in ventricular cardiomyocytes (VCMs) and match increased metabolic demand. Mitochondria from female hearts exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc16c7193cf2b8cedadcf67efa7dafc
https://doi.org/10.1007/s00395-023-00988-1
https://doi.org/10.1007/s00395-023-00988-1
Autor:
Benjamin Martin, Matthew W. Gorr, Richard T. Clements, Fruzsina Perger, Sandor Gyorke, Benjamin Hernandez Orengo, Dmitry Terentyev, Andriy E. Belevych, Radmila Terentyeva, Shanna Hamilton
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 321:H615-H632
Defective intracellular Ca2+ homeostasis and aberrant mitochondrial function are common features in cardiac disease. Here, we directly compared potential benefits of mito-ROS scavenging and restoration of mito-Ca2+ uptake by overexpressing MCU in ven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb9530054661e309d66567bb924a2cb
https://doi.org/10.1152/ajpheart.00126.2021
https://doi.org/10.1152/ajpheart.00126.2021
Autor:
Richard T. Clements, Shanna Hamilton, Dmitry Terentyev, Andriy E. Belevych, Radmila Terentyeva
Publikováno v:
J Mol Cell Cardiol
Sudden cardiac death due to ventricular tachyarrhythmias remains the major cause of mortality in the world. Heart failure, diabetic cardiomyopathy, old age-related cardiac dysfunction and inherited disorders are associated with enhanced propensity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88bc40c855ee063c21fe5ce2214f4d1
https://doi.org/10.1016/j.yjmcc.2021.04.002
https://doi.org/10.1016/j.yjmcc.2021.04.002
Autor:
Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Benjamin Martin, Sandor Gyorke, Andriy Belevych, Gyorgy Csordas, Dmitry Terentyev
Publikováno v:
Circulation Research. 131
Intracellular Ca 2+ cycling in ventricular myocytes (VMs) is tightly linked to mitochondrial metabolic output, and disturbances in this coupling contribute to cardiac arrhythmias. We recently demonstrated in the heritable arrhythmia syndrome catechol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e082521adb52c46df41c68c16318a4e4
https://doi.org/10.1161/res.131.suppl_1.p1083
https://doi.org/10.1161/res.131.suppl_1.p1083