Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Radka, Saldova"'
Autor:
John MacSharry, Zsuzsanna Kovács, Yongjing Xie, Barbara Adamczyk, Caitriona Walsh, Fiona Reidy, Fionnuala M. McAuliffe, Mark T Kilbane, Patrick J Twomey, Pauline M. Rudd, Mary Wingfield, Michael Butler, Douwe van Sinderen, Louise Glover, Radka Saldova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Endometriosis is a chronic systemic disease, which results in endometrial-type tissue growing outside the uterus, and affects approximately 10% of reproductive-aged women worldwide. Its aetiology is poorly understood, and there is currently
Externí odkaz:
https://doaj.org/article/ef1996e4550a4323a3450985ca3ec339
Autor:
Grace Mealy, Kiva Brennan, Sarah Louise Killeen, Mark Kilbane, Cara Yelverton, Radka Saldova, David Groeger, Douwe VanSinderen, Paul D. Cotter, Sarah L. Doyle, Fionnuala M. McAuliffe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Immunological adaptions during pregnancy play a crucial role in healthy fetal development. Aberrant immune modifications however contribute to adverse pregnancy outcomes, which may be driven by maternal factors such as previous pregnancies a
Externí odkaz:
https://doaj.org/article/fbc8cf7673514c788ec84f13dd248dc7
Autor:
Gillian A. Corbett, Rebecca Moore, Conor Feehily, Sarah Louise Killeen, Eileen O'Brien, Douwe Van Sinderen, Elizabeth Matthews, Roisin O'Flaherty, Pauline M. Rudd, Radka Saldova, Calum J. Walsh, Elaine M. Lawton, David A. MacIntyre, Siobhan Corcoran, Paul D. Cotter, Fionnuala M. McAuliffe
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT The vaginal microbiome is a key player in the etiology of spontaneous preterm birth. This study aimed to illustrate maternal environmental factors associated with vaginal microbiota composition and function in pregnancy. Women in healthy pre
Externí odkaz:
https://doaj.org/article/c99e2c423c9242f697d7dd47b6efad8a
Autor:
Büşra Günay, Elizabeth Matthews, Jack Morgan, Marianna A. Tryfonidou, Radka Saldova, Abhay Pandit
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 8, Pp 321-335 (2023)
Abstract Degeneration of the intervertebral disc is an age‐related condition. It also accompanies the disappearance of the notochordal cells, which are remnants of the developmental stages of the nucleus pulposus (NP). Molecular changes such as ext
Externí odkaz:
https://doaj.org/article/a277ae4a05d344ca8e6de75ab1dc08ae
Autor:
Zsuzsanna Kovács, Fiona Reidy, Louise Glover, Fionnuala M. McAuliffe, Henning Stockmann, Mark T. Kilbane, Patrick J. Twomey, Maire Peters, Merli Saare, Pauline M. Rudd, Meeme Utt, Mary Wingfield, Andres Salumets, Radka Saldova
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Endometriosis is a chronic inflammatory gynaecological disease characterized by the growth of endometrial tissue outside the uterine cavity. There are currently no definitive non-invasive diagnostic tools. Glycosylation is the most common po
Externí odkaz:
https://doaj.org/article/49ca3df7f2d745ffbebbe0c88f41066c
Autor:
Conor Feehily, Ian J. O’Neill, Calum J. Walsh, Rebecca L. Moore, Sarah Louise Killeen, Aisling A. Geraghty, Elaine M. Lawton, David Byrne, Rocio Sanchez-Gallardo, Sai Ravi Chandra Nori, Ida Busch Nielsen, Esther Wortmann, Elizabeth Matthews, Roisin O’Flaherty, Pauline M. Rudd, David Groeger, Fergus Shanahan, Radka Saldova, Fionnuala M. McAuliffe, Douwe Van Sinderen, Paul D. Cotter
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract A significant proportion of the infant gut microbiome is considered to be acquired from the mother during and after birth. Thus begins a lifelong and dynamic relationship with microbes that has an enduring impact on host health. Based on a c
Externí odkaz:
https://doaj.org/article/26650c16de684337b8c9307fea1f8d0c
Autor:
Óscar Lado-Baleato, Jorge Torre, Róisín O’Flaherty, Manuela Alonso-Sampedro, Iago Carballo, Carmen Fernández-Merino, Carmen Vidal, Francisco Gude, Radka Saldova, Arturo González-Quintela
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 17 (2023)
(1) Aim: To describe, in a general adult population, the serum N-glycome in relation to age in men and women, and investigate the association of N-glycome patterns with age-related comorbidity; (2) Methods: The serum N-glycome was studied by hydrophi
Externí odkaz:
https://doaj.org/article/dc4a9f0e86bc4a04b86101a1aa12a0d2
Publikováno v:
Journal of Advanced Research, Vol 33, Iss , Pp 167-181 (2021)
Background: Endometriosis is a chronic gynaecological disease whose aetiology is still unknown. Despite its prevalence among women of reproductive age, the pathology of the disease has not yet been elucidated and only symptomatic treatment is availab
Externí odkaz:
https://doaj.org/article/1051222bdf6b43ddb40c83e9cb0986ab
Autor:
Eileen P. Treacy, Sebastian Vencken, Annet M. Bosch, Matthias Gautschi, Estela Rubio‐Gozalbo, Charlotte Dawson, Darragh Nerney, Hugh Owen Colhoun, Loai Shakerdi, Gregory M. Pastores, Roisin O'Flaherty, Radka Saldova
Publikováno v:
JIMD Reports, Vol 61, Iss 1, Pp 76-88 (2021)
Abstract Background Classical galactosemia (CG) (OMIM #230400) is a rare disorder of carbohydrate metabolism, due to deficiency of galactose‐1‐phosphate uridyltransferase (EC 2.7.7.12). The pathophysiology of the long‐term complications, mainly
Externí odkaz:
https://doaj.org/article/f9282f77401549bb87780cfc6729c8e5
Autor:
Ana Lúcia Rebelo, Francesco Gubinelli, Pauline Roost, Caroline Jan, Emmanuel Brouillet, Nadja Van Camp, Richard R. Drake, Radka Saldova, Abhay Pandit
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background Neuroinflammation is an underlying pathology of all neurological conditions, the understanding of which is still being comprehended. A specific molecular pathway that has been overlooked in neuroinflammation is glycosylation (i.e.
Externí odkaz:
https://doaj.org/article/75a88742339b45babd60175335bcb9d7