Zobrazeno 1 - 10
of 5 635
pro vyhledávání: '"Radiosensitization"'
Autor:
Chih-Chia Yu, Hon-Yi Lin, Michael W.Y. Chan, Shu-Fen Wu, Wen-Yen Chiou, Moon-Sing Lee, Chen-Lin Chi, Ru-Inn Lin, Feng-Chun Hsu, Hsuan-Ju Yang, Liang-Cheng Chen, Chia-Hui Chew, Shih-Kai Hung
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Purpose We tested whether the PARP inhibitor, Olaparib, can effectively enhance radiosensitivity while inhibiting OSCC growth and metastasis in vitro and in vivo. Patient samples were used for survival validation. Methods The present study i
Externí odkaz:
https://doaj.org/article/96733e60a5754353b2b87055a4217001
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-8 (2024)
Abstract Purpose Nanoparticles (NPs) as radiosensitizers present a promising strategy for enhancing radiotherapy effectiveness, but their potential is significantly influenced by the properties of their surface coating, which can impact treatment out
Externí odkaz:
https://doaj.org/article/c8a00e597450451d9ceefc4962af4ca6
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-20 (2024)
Abstract Radiotherapy is prevalently applied for highly effective cancer therapy while the low specificity of radiation is deleterious to the nearby healthy cells. High-Z-based nanomaterials offer excellent radio-enhancement properties while natural
Externí odkaz:
https://doaj.org/article/c7d76ec2e9524d5baa90bd004bc36de7
Autor:
Xin Wen, Zhiying Shao, Xueting Chen, Hongmei Liu, Hui Qiu, Xin Ding, Debao Qu, Hui Wang, Andrew Z. Wang, Longzhen Zhang
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-20 (2024)
Abstract Glioblastoma (GBM), the most common primary brain malignancy in adults, is notoriously difficult to treat due to several factors: tendency to be radiation resistant, the presence of the blood brain barrier (BBB) which limits drug delivery an
Externí odkaz:
https://doaj.org/article/ac79f3ab66934c71b016444172807920
Autor:
Charlotte Degorre, Steven Lohard, Christina N. Bobrek, Komal N. Rawal, Skyler Kuhn, Philip J. Tofilon
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract PRMT5 is a widely expressed arginine methyltransferase that regulates processes involved in tumor cell proliferation and survival. In the study described here, we investigated whether PRMT5 provides a target for tumor radiosensitization. Kno
Externí odkaz:
https://doaj.org/article/1277a2b62112434899d4c69804c491f9
Autor:
Marc Zuckermann, Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Brandon Bianski, Jia Xie, Yingzhe Wang, Nathaniel Twarog, Arzu Onar-Thomas, Kati J. Ernst, Lei Yang, Yong Li, Xiaoyan Zhu, Jennifer K. Ocasio, Kaitlin M. Budd, James Dalton, Xiaoyu Li, Divyabharathi Chepyala, Junyuan Zhang, Ke Xu, Laura Hover, Jordan T. Roach, Kenneth Chun-Ho Chan, Nina Hofmann, Peter J. McKinnon, Stefan M. Pfister, Anang A. Shelat, Zoran Rankovic, Burgess B. Freeman, Jason Chiang, David T. W. Jones, Christopher L. Tinkle, Suzanne J. Baker
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Pediatric-type diffuse high-grade glioma (pHGG) is the most frequent malignant brain tumor in children and can be subclassified into multiple entities. Fusion genes activating the MET receptor tyrosine kinase often occur in infant
Externí odkaz:
https://doaj.org/article/c4e30eaef7d54080a0db2c1628bcebbf
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102092- (2024)
CDK4/6 inhibitors combined with endocrine therapy prolonged survival in hormone receptor (HR)-positive and HER2-negative advanced breast cancer. We investigated whether CDK4/6 inhibitors enhance radiosensitivity and their underlying mechanisms of thi
Externí odkaz:
https://doaj.org/article/1de44e4112724428b5c89026680f9140
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 4, Pp 1787-1800 (2024)
Radiotherapy (RT) is one of the most feasible and routinely used therapeutic modalities for treating malignant tumors. In particular, immune responses triggered by RT, known as radio-immunotherapy, can partially inhibit the growth of distantly spread
Externí odkaz:
https://doaj.org/article/cc94dd1e7c7847098452ebe520140be5
Autor:
Yajun Wu, Pengyuan Liu, Wendy Chen, Shiting Bai, Sisi Chen, Jianglin Chen, Xiaogang Xu, Jindan Xia, Yufei Wu, Jianjun Lai, Chuan Sun, Zhenghong Lao, Xiaoqing Wan, Zhibing Wu
Publikováno v:
International Journal of Hyperthermia, Vol 41, Iss 1 (2024)
AbstractPurpose Radiotherapy (RT) is the primary treatment for prostate cancer (PCa); however, the emergence of castration-resistant prostate cancer (CRPC) often leads to treatment failure and cancer-related deaths. In this study, we aimed to explore
Externí odkaz:
https://doaj.org/article/2856eb9f8da747f3922e18870ddc12cd
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