Zobrazeno 1 - 10
of 473
pro vyhledávání: '"Radioprotective Agent"'
Autor:
Yun-Xuan Ge, Zhuo Zhang, Jia-Yi Yan, Zeng-Chun Ma, Yu-Guang Wang, Cheng-Rong Xiao, Xiao-Mei Zhuang, Yue Gao
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3047 (2024)
E0703, a new steroidal compound optimized from estradiol, significantly increased cell proliferation and the survival rate of KM mice and beagles after ionizing radiation. In this study, we characterize its preclinical pharmacokinetics (PK) and predi
Externí odkaz:
https://doaj.org/article/0ce09827aec2489aadb627f93a4ca80d
Publikováno v:
AIMS Molecular Science, Vol 10, Iss 1, Pp 52-69 (2023)
The search for potent radiation-protective drugs for clinical use continues. Studies have, so far, focused on targeting the neutralization of radiation-generated reactive oxygen species (ROS) to protect the cells against the deleterious effects of ex
Externí odkaz:
https://doaj.org/article/ccb8c9fe35ef432184df974cef2c1f0f
Publikováno v:
Journal of Biomedical Physics and Engineering, Vol 12, Iss 3, Pp 245-256 (2022)
Background: Rosemary plant, with phenolic compounds, is known as an antioxidant herb and able to scavenge free radical agents in the biological environment; therefore, it is expected that the rosemary essential oil (R-EO) shows the radioprotective ef
Externí odkaz:
https://doaj.org/article/178c35918c144688b6a9b43420b3b793
Autor:
Hanming Zhang, Zhiyun Meng, Tong Ye, Taoyun Liu, Jian Li, Fei Ma, Ruolan Gu, Xiaoxia Zhu, Zhuona Wu, Guifang Dou, Hui Gan
Publikováno v:
Radiation Medicine and Protection, Vol 2, Iss 2, Pp 72-78 (2021)
Objective: To develop an UPLC-MS/MS method for the accurate quantification of Estriol (E3), a new radioprotective agent, and observe the variation in pharmacokinetic characteristics of E3 after irradiation. As a hormone drug, the gender differences o
Externí odkaz:
https://doaj.org/article/f13465a23a6b4f2b967d0c58c9a31c10
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPrevious analysis of the study (NCT02577393) had demonstrated the application of epigallocatechin-3-gallate (EGCG) could be safe and effective in the prevention and treatment of acute radiation esophagitis in patients with advanced lung can
Externí odkaz:
https://doaj.org/article/be7d2c2c99f7440d93e004c314826c2e
Publikováno v:
Molecules, Vol 27, Iss 10, p 3298 (2022)
Radiotherapy is a common method to treat cancers, with the goal of maximizing the dose to tumors while minimizing the dose to normal tissues. Radioprotectors can reduce the toxicity to normal tissues during radiotherapy. Several plant-derived compoun
Externí odkaz:
https://doaj.org/article/a30e47519e3f43c9b5a7452d6a00079e
Autor:
Shin-ichi Hirano, Yusuke Ichikawa, Bunpei Sato, Haru Yamamoto, Yoshiyasu Takefuji, Fumitake Satoh
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4566 (2021)
Although ionizing radiation (radiation) is commonly used for medical diagnosis and cancer treatment, radiation-induced damages cannot be avoided. Such damages can be classified into direct and indirect damages, caused by the direct absorption of radi
Externí odkaz:
https://doaj.org/article/f9a8f0a4d24f41d7baad27c4725d0d34