Zobrazeno 1 - 10
of 444
pro vyhledávání: '"Radiopharmaceutical therapy"'
Autor:
Cassandra Miller, Ivan Klyuzhin, Guillaume Chaussé, Julia Brosch-Lenz, Helena Koniar, Kuangyu Shi, Arman Rahmim, Carlos Uribe
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-19 (2024)
Abstract Background Radiopharmaceutical therapy with 225Ac- and 177Lu-PSMA has shown promising results for the treatment of prostate cancer. However, the distinct physical properties of alpha and beta radiation elicit varying cellular responses, whic
Externí odkaz:
https://doaj.org/article/6bcb29ad273f43edbffbd9acf10e8d6d
Autor:
Clarita Saldarriaga Vargas, Michelle Andersson, Céline Bouvier-Capely, Wei Bo Li, Balázs Madas, Peter Covens, Lara Struelens, Lidia Strigari
Publikováno v:
Zeitschrift für Medizinische Physik, Vol 34, Iss 4, Pp 491-509 (2024)
Absorbed dose heterogeneity in kidney tissues is an important issue in radiopharmaceutical therapy. The effect of absorbed dose heterogeneity in nephrotoxicity is, however, not fully understood yet, which hampers the implementation of treatment optim
Externí odkaz:
https://doaj.org/article/443f7894555c473e92a2299d257230c9
Publikováno v:
Precision Radiation Oncology, Vol 8, Iss 3, Pp 145-152 (2024)
Abstract Radiopharmaceutical therapy (RPT) is a precision medicine approach that involves the targeted delivery of radioactive atoms to tumor cells, representing a breakthrough strategy for cancer treatment. Radiopharmaceuticals typically consist of
Externí odkaz:
https://doaj.org/article/357c85f975ba430d849d4a1b6b9a8ff7
Autor:
Helena Koniar, Scott McNeil, Luke Wharton, Aidan Ingham, Michiel Van de Voorde, Maarten Ooms, Sathiya Sekar, Cristina Rodríguez-Rodríguez, Peter Kunz, Valery Radchenko, Arman Rahmim, Carlos Uribe, Hua Yang, Paul Schaffer
Publikováno v:
EJNMMI Physics, Vol 11, Iss 1, Pp 1-18 (2024)
Abstract Background Element-equivalent matched theranostic pairs facilitate quantitative in vivo imaging to establish pharmacokinetics and dosimetry estimates in the development of preclinical radiopharmaceuticals. Terbium radionuclides have signific
Externí odkaz:
https://doaj.org/article/94275ecfb96241b988df7d40866a532c
Autor:
Robin Peter, Anil P. Bidkar, Kondapa Naidu Bobba, Luann Zerefa, Chandrashekhar Dasari, Niranjan Meher, Anju Wadhwa, Adam Oskowitz, Bin Liu, Brian W. Miller, Kai Vetter, Robert R. Flavell, Youngho Seo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Radiopharmaceutical therapy using $$\upalpha$$ α -emitting $$^{225}$$ 225 Ac is an emerging treatment for patients with advanced metastatic cancers. Measurement of the spatial dose distribution in organs and tumors is needed to inform treat
Externí odkaz:
https://doaj.org/article/e1d2c9d4e31443c086a6151ba318828e
Autor:
A. V. Petryakova, L. A. Chipiga, I. A. Zvonova, A. V. Vodovatov, G. A. Gorsky, A. A. Stanzhevsky
Publikováno v:
Радиационная гигиена, Vol 17, Iss 2, Pp 97-108 (2024)
Radiopharmaceutical therapy with 131I has been one of the most common types of radiopharmaceutical therapy for many years. Radiation safety of the public is ensured by limiting the patient contacts until the radiological parameters are reduced to the
Externí odkaz:
https://doaj.org/article/22dd257347ff46b8afaaa3b1a313b3d9
Autor:
Rajan Singh, Anand K. Thotakura, Suresh Alati, Alla Lisok, Zirui Jiang, Vanessa F. Merino, Il Minn, Santosh Yadav, Mark C. Markowski, Yasser Ged, Christian P. Pavlovich, Nirmish Singla, Lilja B. Solnes, Michael A. Gorin, Martin G. Pomper, Steven P. Rowe, Sangeeta Ray Banerjee
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionRenal cell carcinoma (RCC) represents cancer originating from the renal epithelium and accounts for > 90% of cancers in the kidney. Prostate-specific membrane antigen (PSMA) is overexpressed in tumor-associated neovascular endothelial cel
Externí odkaz:
https://doaj.org/article/0b43bcfa255e43f883bee194298d2a44
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Background We aimed to develop a publicly shared computational physiologically based pharmacokinetic (PBPK) model to reliably simulate and analyze radiopharmaceutical therapies (RPTs), including probing of hot-cold ligand competitions as wel
Externí odkaz:
https://doaj.org/article/670a025dd79c4357aa0641975174624b
Autor:
Amanda G. Shea, Malick Bio Idrissou, Ana Isabel Torres, Tessa Chen, Reiner Hernandez, Zachary S. Morris, Quaovi H. Sodji
Publikováno v:
Frontiers in Nuclear Medicine, Vol 4 (2024)
Radiation therapy (RT) is a pillar of cancer therapy used by more than half of all cancer patients. Clinically, RT is mostly delivered as external beam radiation therapy (EBRT). However, the scope of EBRT is limited in the metastatic setting, where a
Externí odkaz:
https://doaj.org/article/4e5793cbbf8a4645b5099ead59e87c79
Autor:
Keamogetswe Ramonaheng, Milani Qebetu, Honest Ndlovu, Cecile Swanepoel, Liani Smith, Sipho Mdanda, Amanda Mdlophane, Mike Sathekge
Publikováno v:
Frontiers in Nuclear Medicine, Vol 4 (2024)
Radiopharmaceutical therapy has been widely adopted owing primarily to the development of novel radiopharmaceuticals. To fully utilize the potential of these RPTs in the era of precision medicine, therapy must be optimized to the patient's tumor char
Externí odkaz:
https://doaj.org/article/4794ca85e16b4a0db1257b342ed98e13