Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Radiology and Medical Imaging/Radionuclide Imaging"'
Autor:
Karel Pacak, Jie Lu, Zhengping Zhuang, Jeffrey Chiang, Lucia Martiniova, Marcelino Bernardo, Russell R. Lonser
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14678 (2011)
PLoS ONE
PLoS ONE
Background The failure of cytotoxic cancer regimens to cure the most drug-resistant, well-differentiated solid tumors has been attributed to the heterogeneity of cell types that differ in their capacities for growth, differentiation, and metastases.
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10857 (2010)
PLoS ONE
PLoS ONE
Background Carbonic anhydrase IX (CAIX) is a membrane spanning protein involved in the enzymatic regulation of tumor acid-base balance. CAIX has been shown to be elevated in a number of hypoxic tumor types. The purpose of this study was to determine
Autor:
Jason S. Lewis, Valerie A. Longo, Tony Taldone, Gabriela Chiosis, Vadim Divilov, Eloisi Caldas-Lopes, Jason P. Holland, Danuta Zatorska
Publikováno v:
PLoS ONE
Background The positron-emitting radionuclide 89Zr (t 1/2 = 3.17 days) was used to prepare 89Zr-radiolabeled trastuzumab for use as a radiotracer for characterizing HER2/neu-positive breast tumors. In addition, pharmacodynamic studies on HER2/neu exp
Autor:
Mario Vallon, Florian C. Gaertner, Frank Bruchertseifer, Enken Drecoll, Birgit Blechert, Reingard Senekowitsch-Schmidtke, Jan Müller, Matthias Miederer, Alfred Morgenstern, Christof Seidl, Markus Essler, Andrea Alke
Publikováno v:
PLoS ONE
BACKGROUND: Alpha-particle emitting isotopes are effective novel tools in cancer therapy, but targeted delivery into tumors is a prerequisite of their application to avoid toxic side effects. Peritoneal carcinomatosis is a widespread dissemination of
Autor:
Hedvig Hricak, Jatin P. Shah, Sheng Gang, Peter Brader, Ronald G. Blasberg, Yuman Fong, Ziv Gil, Kaitlyn J. Kelly, Richard J. Wong
Publikováno v:
PLoS ONE
Background In patients with melanoma, knowledge of regional lymph node status provides important information on outlook. Since lymph node status can influence treatment, surgery for sentinel lymph node (SLN) biopsy became a standard staging procedure
Autor:
Douglas R. Smyth, Michael P. Brown, Jim Manavis, Chris Tsopelas, Fares Al-Ejeh, Jocelyn M. Darby
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 2, p e4558 (2009)
PLoS ONE, Vol 4, Iss 2, p e4558 (2009)
Background: Antineoplastic therapy may impair the survival of malignant cells to produce cell death. Consequently, direct measurement of tumor cell death in vivo is a highly desirable component of therapy response monitoring. We have previously shown
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13300 (2010)
PLoS ONE, Vol 5, Iss 10, p e13300 (2010)
Background Positron emission tomography (PET) allows sensitive, non-invasive analysis of the distribution of radiopharmaceutical tracers labeled with positron (β+)-emitting radionuclides in small animals and humans. Upon β+ decay, the initial veloc
Autor:
John J. You, Marian J. Vermeulen, Astrid Guttmann, Joel G. Ray, Marcelo L. Urquia, Michael J. Schull
Publikováno v:
PLoS Medicine, Vol 7, Iss 9, p e1000337 (2010)
PLoS Medicine
PLoS Medicine
In a record-linkage study, Joel Ray and colleagues examine the association between diagnostic imaging during pregnancy and later childhood cancers.
Background The association between fetal exposure to major radiodiagnostic testing in pregnancy
Background The association between fetal exposure to major radiodiagnostic testing in pregnancy