Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Radiology and Medical Imaging/PET and SPECT Imaging"'
Autor:
Karel Pacak, Jie Lu, Zhengping Zhuang, Jeffrey Chiang, Lucia Martiniova, Marcelino Bernardo, Russell R. Lonser
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14678 (2011)
PLoS ONE
PLoS ONE
Background The failure of cytotoxic cancer regimens to cure the most drug-resistant, well-differentiated solid tumors has been attributed to the heterogeneity of cell types that differ in their capacities for growth, differentiation, and metastases.
Autor:
Nicolas Beaudet, Louis Gendron, Mélanie Archambault, Philippe Sarret, Myriam Lemire, Jean-François Beaudoin, Karine Belleville, Roger Lecomte, Valérie Otis, Martin Lepage, Luc Tremblay, Louis Doré-Savard
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13774 (2010)
PLoS ONE
PLoS ONE
Pre-clinical bone cancer pain models mimicking the human condition are required to respond to clinical realities. Breast or prostate cancer patients coping with bone metastases experience intractable pain, which affects their quality of life. Advance
Autor:
Kamille Dumong Erichsen, Peter Buhl Jensen, Mette Munk Jensen, Fredrik Björkling, Maxwell Sehested, Jacob Madsen, Andreas Kjaer, Liselotte Højgaard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 9, p e12965 (2010)
PLoS ONE, Vol 5, Iss 9, p e12965 (2010)
BACKGROUND: 3'-Deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) is a tracer used to assess cell proliferation in vivo. The aim of the study was to use (18)F-FLT positron emission tomography (PET) to study treatment responses to a new anti-cancer compound.
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10857 (2010)
PLoS ONE
PLoS ONE
Background Carbonic anhydrase IX (CAIX) is a membrane spanning protein involved in the enzymatic regulation of tumor acid-base balance. CAIX has been shown to be elevated in a number of hypoxic tumor types. The purpose of this study was to determine
Localized fetomaternal hyperglycemia: spatial and kinetic definition by positron emission tomography
Autor:
John Sunderland, Shanming Hu, Jianrong Yao, Jeffrey L. Segar, Laura L. Boles Ponto, Chunlin Wang, Alexander B. Sawatzke, Andrew W. Norris, Diana Dang, Susan A. Walsh
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 8, p e12027 (2010)
PLoS ONE, Vol 5, Iss 8, p e12027 (2010)
Background: Complex but common maternal diseases such as diabetes and obesity contribute to adverse fetal outcomes. Understanding of the mechanisms involved is hampered by difficulty in isolating individual elements of complex maternal states in vivo
Autor:
Zhen Cheng, Zheng Miao, Peizhen Han, Gang Ren, Sanjiv S. Gambhir, Xiaofen Zhang, Hongguang Liu, Xiaodong Tang
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9470 (2010)
PLoS ONE
PLoS ONE
Background Optical imaging (OI) techniques such as bioluminescence and fluorescence imaging have been widely used to track diseases in a non-invasive manner within living subjects. These techniques generally require bioluminescent and fluorescent pro
Autor:
Jason S. Lewis, Valerie A. Longo, Tony Taldone, Gabriela Chiosis, Vadim Divilov, Eloisi Caldas-Lopes, Jason P. Holland, Danuta Zatorska
Publikováno v:
PLoS ONE
Background The positron-emitting radionuclide 89Zr (t 1/2 = 3.17 days) was used to prepare 89Zr-radiolabeled trastuzumab for use as a radiotracer for characterizing HER2/neu-positive breast tumors. In addition, pharmacodynamic studies on HER2/neu exp
Autor:
Hsin Hsin Yeh, Uday Mukhopadhyay, Suren Soghomonyan, Craig D. Logsdon, Ashutosh Pal, Yunming Ying, Susanna Bertolini, Andrei Volgin, Mian M. Alauddin, Aleksandr Shavrin, William G. Bornmann, Daniel Young, William P. Tong, Juri G. Gelovani, Leo G. Flores
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 11, p e7977 (2009)
PLoS ONE, Vol 4, Iss 11, p e7977 (2009)
Background Early diagnosis of pancreatic carcinoma with highly sensitive diagnostic imaging methods could save lives of many thousands of patients, because early detection increases resectability and survival rates. Current non-invasive diagnostic im
Autor:
David L. Wilson, Christopher L. King, Jing Wang, Zhenghong Lee, James P. Basilion, Jason D. Balkman, Nicolas Salem
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 4, Iss 9 (2010)
PLoS Neglected Tropical Diseases, Vol 4, Iss 9 (2010)
Background Schistosomes are chronic intravascular helminth parasites of humans causing a heavy burden of disease worldwide. Diagnosis of schistosomiasis currently requires the detection of schistosome eggs in the feces and urine of infected individua
Autor:
Hedvig Hricak, Jatin P. Shah, Sheng Gang, Peter Brader, Ronald G. Blasberg, Yuman Fong, Ziv Gil, Kaitlyn J. Kelly, Richard J. Wong
Publikováno v:
PLoS ONE
Background In patients with melanoma, knowledge of regional lymph node status provides important information on outlook. Since lymph node status can influence treatment, surgery for sentinel lymph node (SLN) biopsy became a standard staging procedure