Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Radioconjugate"'
Autor:
Stephen J. Archibald, Louis Allott
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-28 (2021)
Abstract The aluminium-[18F]fluoride ([18F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal-based radiochemistry and has been used to parallel gallium-68 radiopharma
Externí odkaz:
https://doaj.org/article/4e5f06acee8545c78faf7d07f37f6c28
Akademický článek
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Autor:
Ala Amgheib, Ruisi Fu, Marta Braga, Sadaf Ghaem-Maghami, Chris P. Barnes, Louis Allott, Eric O. Aboagye, Ning Wang, Diana Brickute
Publikováno v:
Reaction Chemistry & Engineering
The use of biologics in positron emission tomography (PET) imaging is an important area of radiopharmaceutical development and new automated methods are required to facilitate their production. We report an automated radiosynthesis method to produce
Autor:
Frank Bruchertseifer, Peter Covens, Mireille Gysemans, Yana Dekempeneer, Catarina Xavier, Quentin Lecocq, Vicky Caveliers, Thomas Cardinaels, Maarten Ooms, Ken Maes, Brian Miller, Tony Lahoutte, Matthias D'Huyvetter, Dominic Maertens, Alfred Morgenstern
Publikováno v:
Molecular Pharmaceutics. 17:3553-3566
Targeted alpha-particle therapy (TAT) might be a relevant therapeutic strategy to circumvent resistance to conventional therapies in the case of HER2-positive metastatic cancer. Single-domain antibody fragments (sdAb) are promising vehicles for TAT b
Autor:
Louis Allott, Stephen J. Archibald
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 6, Iss 1, Pp 1-28 (2021)
EJNMMI Radiopharmacy and Chemistry
EJNMMI Radiopharmacy and Chemistry
The aluminium-[18F]fluoride ([18F]AlF) radiolabelling method combines the favourable decay characteristics of fluorine-18 with the convenience and familiarity of metal-based radiochemistry and has been used to parallel gallium-68 radiopharmaceutical
Autor:
Peter Bartenstein, Markus Kellner, Guido Böning, Franz Josef Gildehaus, Sibylle Ziegler, Reinhard Zeidler, Simon Lindner, Luise Fiedler, Rosel Oos
Publikováno v:
ChemMedChem 13, 1230-1237 (2018)
64 Cu is a cyclotron-produced radionuclide which offers, thanks to its characteristic decay scheme, the possibility of combining positron emission tomography (PET) investigations with radiotherapy. We evaluated the Alceo system from Comecer SpA to au
Autor:
Nathalie L. Albert, Peter Bartenstein, Simon Lindner, Hans-Jürgen Reulen, Rosel Oos, M. Kellner, Astrid Gosewisch, Reinhard Zeidler, Franz-Josef Gildehaus, Luise Fiedler, Guido Böning
Publikováno v:
Nuclear Medicine and Biology. 60:55-62
Introduction Due to their infiltrative growth behavior, gliomas have, even after surgical resection, a high recurrence tendency. The approach of intracavitary radioimmunotherapy (RIT) is aimed at inhibiting tumor re-growth by directly administering d
Autor:
Ramezan Behzadi, Narjes Jafari, Farzaneh Rezazadeh, Iman Emrarian, Seyed Mohammad Abedi, Nourollah Sadeghzadeh, Saeid Abediankenari, Mohsen Mohammadgholi
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 316:595-607
In this study, we introduce a new 99mTc-radiolabeled bombesin derivative for imaging of prostate cancer (PC). We used 6-hydrazinonicotinamide (HYNIC) as bi-functional chelating agent and tricine/ethylenediamine diacetic acid (EDDA) as an exchange co-
Akademický článek
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Autor:
Kumar Prabhash, Akanksha Jain, Mythili Kameswaran, Usha Pandey, Ashutosh Dash, Haladhar Dev Sarma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 27:4552-4557
Molecular imaging using radiolabeled Tyrosine Kinase Inhibitors (TKI) is a promising strategy for detection and staging of EGFR-positive cancers. A novel analogue of one such TKI, Erlotinib has been developed for PET imaging by derivatizing the paren