Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Radiation sensitization"'
Publikováno v:
陆军军医大学学报, Vol 46, Iss 12, Pp 1344-1352 (2024)
Objective To investigate the radiosensitizating effect of quercetin (QU) loaded manganese dioxide nanoparticles [Mn(QU)] on breast cancer cell line 4T1 and tumour-bearing mice. Methods Manganese dioxide (MnO2) nanoparticles were synthesized by oleic
Externí odkaz:
https://doaj.org/article/1afece92f7664d6d993597b2cdb10d6b
Autor:
Sushmitha Sriramulu, Shivani Thoidingjam, Wei-Min Chen, Oudai Hassan, Farzan Siddiqui, Stephen L. Brown, Benjamin Movsas, Michael D. Green, Anthony J. Davis, Corey Speers, Eleanor Walker, Shyam Nyati
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer subtype often treated with radiotherapy (RT). Due to its intrinsic heterogeneity and lack of effective targets, it is crucial to identify novel mole
Externí odkaz:
https://doaj.org/article/bec285331eba422bb5e204315df583c6
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32598- (2024)
Radiotherapy causes apoptosis mainly through direct or indirect damage to DNA via ionizing radiation, leading to DNA strand breaks. However, the efficacy of radiotherapy is attenuated in malignant tumor microenvironment (TME), such as hypoxia. Tumor
Externí odkaz:
https://doaj.org/article/5feab00d8965497e80310e1701c69b11
Autor:
Melissa Schwab, Ali Bashiri Dezfouli, Mohammad Khosravi, Bayan Alkotub, Lisa Bauer, Mohammad Javed Tahmasebi Birgani, Gabriele Multhoff
Publikováno v:
Radiation Oncology, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background An enhanced aerobic glycolysis (“Warburg effect”) associated with an increase in lactic acid in the tumor microenvironment contributes to tumor aggressiveness and resistance to radiation and chemotherapy. We investigated the r
Externí odkaz:
https://doaj.org/article/c683673f154c45f5ac78ef2a38c8ea32
Autor:
Guo, Zhili a, b, c, Lei, Lingling a, b, Zhang, Zenan a, b, c, Du, Meng a, b, Chen, Zhiyi a, b, d, ⁎
Publikováno v:
In Heliyon 30 June 2024 10(12)
Akademický článek
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Akademický článek
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Autor:
Yandong Xie, Mingxi Liu, Chang Cai, Chengkun Ye, Tangjun Guo, Kun Yang, Hong Xiao, Xianglong Tang, Hongyi Liu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Surgical resection and postoperative radiotherapy remained the most common therapeutic modalities for malignant tumors. However, tumor recurrence after receiving such combination is difficult to be avoided because of high invasiveness and radiation r
Externí odkaz:
https://doaj.org/article/01ce76ca950b415c898ed7fa935170ca
Autor:
Lina Xie, Xujia Zhang, Chengchao Chu, Yingqi Dong, Tianzi Zhang, Xinyue Li, Gang Liu, Wen Cai, Suxia Han
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Gold nanorods (GNRs) have a broad application prospect in biomedical fields because of their unique properties and controllable surface modification. The element aurum (Au) with high atomic number (high-Z) render GNRs ideal radiosensitive ma
Externí odkaz:
https://doaj.org/article/41a30917f55a45f29b854aeac326508c
Autor:
Li Wang, MD, PhD, Piero Fossati, MD, Harald Paganetti, PhD, Li Ma, PhD, Maura Gillison, MD, PhD, Jeffrey N. Myers, MD, PhD, Eugen Hug, MD, Steven J. Frank, MD
Publikováno v:
International Journal of Particle Therapy, Vol 8, Iss 1, Pp 3-13 (2021)
Head and neck squamous cell carcinomas (HNSCCs) often present as local-regionally advanced disease at diagnosis, for which a current standard of care is x-ray–based radiation therapy, with or without chemotherapy. This approach provides effective l
Externí odkaz:
https://doaj.org/article/63a22265bc0541dea3a22b24e0e927a1