Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Radiation countermeasure"'
Autor:
Eric Russ, Oluseyi O. Fatanmi, Stephen Y. Wise, Alana D. Carpenter, Manoj Maniar, Sergey Iordanskiy, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Exposure to ionizing radiation (IR) presents a formidable clinical challenge. Total-body or significant partial-body exposure at a high dose and dose rate leads to acute radiation syndrome (ARS), the complex pathologic effects that arise fol
Externí odkaz:
https://doaj.org/article/f8b341f1621c4f83a95e9eda4d72246c
Publikováno v:
Animal Models and Experimental Medicine, Vol 6, Iss 4, Pp 329-336 (2023)
Abstract The risk of internal and external exposure to ionizing radiation (IR) has increased alongside the development and implementation of nuclear technology. Therefore, serious security issues have emerged globally, and there has been an increase
Externí odkaz:
https://doaj.org/article/be5f23dc7d3041e1bc2ad5ca2f1c6115
Autor:
Neetha Nanoth Vellichirammal, Sahil Sethi, Nagavardhini Avuthu, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda, Vijay K. Singh
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract The risk of exposure of the general public or military personnel to high levels of ionizing radiation from nuclear weapons or radiological accidents is a dire national security matter. The development of advanced molecular biodosimetry metho
Externí odkaz:
https://doaj.org/article/99c4a7b85d414c0bbcf85c39bfb8bbfe
Autor:
Neetha Nanoth Vellichirammal, Sahil Sethi, Sanjit Pandey, Jatinder Singh, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Chittibabu Guda, Vijay K. Singh
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 584-598 (2022)
The focus of radiation biodosimetry has changed recently, and a paradigm shift for using molecular technologies of omic platforms in addition to cytogenetic techniques has been observed. In our study, we have used a nonhuman primate model to investig
Externí odkaz:
https://doaj.org/article/dbd5bc15b1e7407598bea42cda0e0d55
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Jaeeun Ko, Jaehwan Kim, Yang-Kyu Choi, Sang-Soep Nahm, Jayon Kim, Sun-Min Seo, Jin-Seok Seo, Woojong Lee, Weon Kuu Chung, Kidong Eom
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
This study aimed to evaluate the clinical safety and validate the radiomitigative effect of KMRC011, against radiation-induced oral mucositis in beagle dogs. Clinical safety was evaluated by assessing tolerability, complete blood tests, and plasma bi
Externí odkaz:
https://doaj.org/article/3fadb8c5fefd4766aac51b836be3cb6f
Autor:
Hong-Soo Lee, Doo-Wan Cho, Ji-Seok Han, Su-Cheol Han, Sang Keun Woo, Soo-Youn Jun, Woo-Jong Lee, Susie Yoon, Son-Il Pak, Sang-Jin Lee, Eunsol Seong, Eun-Jung Park
Publikováno v:
Journal of Immunotoxicology, Vol 17, Iss 1, Pp 31-42 (2020)
In the study here, the potential applicability of KMRC011 - an agonist of toll-like receptor-5 – as a countermeasure for radiation toxicities was evaluated. Following a single 5.5 Gy total body irradiation (TBI, surface absorbed dose = 7 Gy) of Co6
Externí odkaz:
https://doaj.org/article/ab49c49d45f04616ba9084cd90571b27
Autor:
Tarun K. Garg, Sarita Garg, Isabelle R. Miousse, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Frits van Rhee, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16170 (2022)
Radiation exposure causes acute damage to hematopoietic and immune cells. To date, there are no radioprotectors available to mitigate hematopoietic injury after radiation exposure. Gamma-tocotrienol (GT3) has demonstrated promising radioprotective ef
Externí odkaz:
https://doaj.org/article/ef7776838a0b4613be3f43b6c959d0c1
Autor:
Sarita Garg, Tarun K. Garg, Isabelle R. Miousse, Stephen Y. Wise, Oluseyi O. Fatanmi, Alena V. Savenka, Alexei G. Basnakian, Vijay K. Singh, Martin Hauer-Jensen
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 1895 (2022)
Exposure to high doses of radiation, accidental or therapeutic, often results in gastrointestinal (GI) injury. To date, there are no therapies available to mitigate GI injury after radiation exposure. Gamma-tocotrienol (GT3) is a promising radioprote
Externí odkaz:
https://doaj.org/article/0172642cac77426eb4f9fb4893f02c6a
Autor:
Sweta Sanguri, Damodar Gupta
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Total body irradiation (TBI) results in critical injuries in a dose dependent manner that primarily damages highly proliferating tissues including hematopoietic stem cells (HSCs) and intestinal crypt stem cells etc. This may result in hematopoietic s
Externí odkaz:
https://doaj.org/article/5b9347202c2e4d60bfe13380b7c5c391