Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Radiana Trifonova"'
Autor:
Armon Sharei, Radiana Trifonova, Siddharth Jhunjhunwala, George C Hartoularos, Alexandra T Eyerman, Abigail Lytton-Jean, Mathieu Angin, Siddhartha Sharma, Roberta Poceviciute, Shirley Mao, Megan Heimann, Sophia Liu, Tanya Talkar, Omar F Khan, Marylyn Addo, Ulrich H von Andrian, Daniel G Anderson, Robert Langer, Judy Lieberman, Klavs F Jensen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0118803 (2015)
Intracellular delivery of biomolecules, such as proteins and siRNAs, into primary immune cells, especially resting lymphocytes, is a challenge. Here we describe the design and testing of microfluidic intracellular delivery systems that cause temporar
Externí odkaz:
https://doaj.org/article/4237992de75147fcb1684e435e7acb07
Autor:
Judy Lieberman, Anders Wittrup, Fabio Petrocca, Radiana Trifonova, Lee Adam Wheeler, Minh T.N. Le, Peter Hamar, Adi Gilboa-Geffen
Supplemental Figure 1 shows the stability of EpCAM-AsiCs in serum. Supplemental Figure 2 shows that injection of EpCAM-AsiCs in immunocompetent mice does not trigger innate immunity. Supplemental Figure 3 shows that the siRNA within the AsiC associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1397a6b2d6ba0f06b24a87e311d13989
https://doi.org/10.1158/1535-7163.22506657
https://doi.org/10.1158/1535-7163.22506657
Autor:
Judy Lieberman, Anders Wittrup, Fabio Petrocca, Radiana Trifonova, Lee Adam Wheeler, Minh T.N. Le, Peter Hamar, Adi Gilboa-Geffen
Effective therapeutic strategies for in vivo siRNA delivery to knockdown genes in cells outside the liver are needed to harness RNA interference for treating cancer. EpCAM is a tumor-associated antigen highly expressed on common epithelial cancers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16489e9d1802da3a5a8fbdb70dc71e31
https://doi.org/10.1158/1535-7163.c.6538461.v1
https://doi.org/10.1158/1535-7163.c.6538461.v1
Publikováno v:
Journal of Medical Cases
Oral contraceptive pills (OCPs) have a known prothrombotic effect. Obliterative portal venopathy (OPV) can be seen in patients with underlying hypercoagulability. We present a case of a 19-year-old female patient taking OCPs who presented with obstru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361f40856ec210cb0480d04936a62c8d
http://europepmc.org/articles/PMC8577609
http://europepmc.org/articles/PMC8577609
Publikováno v:
Cureus
Pneumatosis intestinalis (PI) is a rare condition characterized by multiple air-filled cystic lesions in the submucosa or subserosa of the intestine. Despite a limited understanding of its pathogenesis, the causes of PI can be categorized into life-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0554036286b79032d462faa8b76a9695
https://doi.org/10.7759/cureus.12140
https://doi.org/10.7759/cureus.12140
Autor:
Daniel T. Claiborne, Christian L. Boutwell, Timothy Bateson, Meredith Phelps, Radiana Trifonova, James A. Hoxie, Tao Chen, Derrick L. Dopkin, Karen A. Power, Colby R. Maldini, Ken Okawa, George J. Leslie, Xiaochuan Shan, Vladimir Vrbanac, Todd M. Allen, Katharine Krupp, James L. Riley, Serah Tanno
Publikováno v:
Nat Med
An effective strategy to cure HIV will likely require a potent and sustained antiviral T cell response. Here we explored the utility of chimeric antigen receptor (CAR) T cells, expressing the CD4 ectodomain to confer specificity for the HIV envelope,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58e502a9bb70766c6db89848aaf0b33a
https://europepmc.org/articles/PMC9422086/
https://europepmc.org/articles/PMC9422086/
Publikováno v:
Cellular Heterogeneity ISBN: 9781493976799
Imaging flow cytometry (IFC) has become a powerful tool for studying the activation of transcriptional factors in heterogeneous cell populations in high-content imaging mode. With considerable interest to the clinical development of IFC, the question
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbc6c740036701ffa9c8f43e953bdffc
https://doi.org/10.1007/978-1-4939-7680-5_8
https://doi.org/10.1007/978-1-4939-7680-5_8
Autor:
Klaus Charisse, Xing Liu, Muthiah Manoharan, Judy Lieberman, Péter Hamar, Angela Ai, Anders Wittrup, Tomas Kirchhausen, Radiana Trifonova
Publikováno v:
Nature Biotechnology. 33:870-876
A central hurdle in developing small interfering RNAs (siRNAs) as therapeutics is the inefficiency of their delivery across the plasma and endosomal membranes to the cytosol, where they interact with the RNA interference machinery. With the aim of im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11cdae32f926cdba6cf78db86bb4c70
https://doi.org/10.1038/nbt.3298
https://doi.org/10.1038/nbt.3298
Autor:
Michael A. Brehm, Judy Lieberman, Dale L. Greiner, Andrew M. Tager, Vladimir Vrbanac, Adi Gilboa-Geffen, Andrew D. Luster, Lee Adam Wheeler, Serah Tanno, Radiana Trifonova
Publikováno v:
Molecular Therapy. 21(7):1378-1389
The continued spread of HIV underscores the need to interrupt transmission. One attractive strategy, in the absence of an effective vaccine, is a topical microbicide, but the need for application around the time of sexual intercourse leads to poor pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4840a6530218fcb39adafad015bd7b68
Autor:
Judy Lieberman, Adi Gilboa-Geffen, Anders Wittrup, Fabio Petrocca, Radiana Trifonova, Minh T.N. Le, Péter Hamar, Lee Adam Wheeler
Publikováno v:
Molecular cancer therapeutics. 14(10)
Effective therapeutic strategies for in vivo siRNA delivery to knockdown genes in cells outside the liver are needed to harness RNA interference for treating cancer. EpCAM is a tumor-associated antigen highly expressed on common epithelial cancers an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffada74e33890234464faf5d035eb9a
https://pubmed.ncbi.nlm.nih.gov/26264278
https://pubmed.ncbi.nlm.nih.gov/26264278