Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Radhika, Koranne"'
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31a64ebb25ba966393295a552c9a134c
https://doi.org/10.1016/b978-0-12-821618-7.00196-6
https://doi.org/10.1016/b978-0-12-821618-7.00196-6
Autor:
L. M. Viranga Tillekeratne, Ayad Ayad Al-Hamashi, Samkeliso Dlamini, William Taylor, Radhika Koranne, Mary Kay Pflum, Ahmed T. Negmeldin, Joseph Knoff
Publikováno v:
Proceedings, Vol 22, Iss 1, p 63 (2019)
Epigenetic regulation of gene expression without changing DNA sequences is a promising strategy in developing therapeutic agents for human diseases, especially cancer. [...]
Externí odkaz:
https://doaj.org/article/9185cc5d77694202988cc68711419b19
Autor:
Abdulateef Alqahtani, Ayad A. Al-Hamashi, Matthew Dunworth, Joseph R. Knoff, Robert A. Casero, Mary Kay H. Pflum, Lalith Perera, Endri Karaj, L. M. Viranga Tillekeratne, Radhika Koranne, Maisha S. Rashid, Samkeliso Dlamini, William R. Taylor
Publikováno v:
Bioorg Chem
Despite the advances in treatment strategies, cancer is still the second leading cause of death in the USA. A majority of the currently used cancer drugs have limitations in their clinical use due to poor selectivity, toxic side effects and multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fef0848d1028eade72991abcff704bb
https://pubmed.ncbi.nlm.nih.gov/34509798
https://pubmed.ncbi.nlm.nih.gov/34509798
Autor:
Endri, Karaj, Samkeliso, Dlamini, Radhika, Koranne, Shaimaa H, Sindi, Lalith, Perera, William R, Taylor, L M, Viranga Tillekeratne
Publikováno v:
Bioorganic Chemistry. 122:105700
We recently reported a new class of imidazole-based chalcones as potential antimitotic agents. In view of their promising cytotoxic activity, a comprehensive structure-activity relationship (SAR) of these compounds was undertaken focusing on four maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970fd5f8946371e5c16bbc321dca08ad
https://doi.org/10.1016/j.bioorg.2022.105700
https://doi.org/10.1016/j.bioorg.2022.105700
Publikováno v:
Experimental Cell Research. 413:113063
C9ORF78 is a poorly characterized protein found in diverse eukaryotes. Previous work indicated overexpression of C9ORF78 in malignant tissues indicating a possible involvement in growth regulatory pathways. Additional studies in fission yeast and hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86210083b7c0974eaf124178dd13464f
https://doi.org/10.1016/j.yexcr.2022.113063
https://doi.org/10.1016/j.yexcr.2022.113063
Autor:
Radhika Koranne, Mary Kay H. Pflum, Joseph R. Knoff, Samkeliso Dlamini, L. M. Viranga Tillekeratne, Ahmed T. Negmeldin, William R. Taylor, Ayad A. Al-Hamashi
Publikováno v:
Proceedings, Vol 22, Iss 1, p 63 (2019)
Epigenetic regulation of gene expression without changing DNA sequences is a promising strategy in developing therapeutic agents for human diseases, especially cancer. Histone deacetylases (HDACs) are a family of enzymes involved in epigenetic modula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1f0db5f62bb734d22710d99dcc4ce9
https://doi.org/10.3390/proceedings2019022063
https://doi.org/10.3390/proceedings2019022063
Autor:
Samkeliso Dlamini, Sara R. Fedorka, Maisha S. Rashid, William R. Taylor, Veronika Kholodovych, Radhika Koranne, Mark W. Jackson, Tim Rogers, Ayad A. Al-Hamashi, Ibtissam Gad, Damian J. Junk, L. M. Viranga Tillekeratne, Nishanth Kuganesan, Yusuf Barudi, Hanan D. Alqahtani, Ronit Shah
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Effective management of advanced cancer requires systemic treatment including small molecules that target unique features of aggressive tumor cells. At the same time, tumors are heterogeneous and current evidence suggests that a subpopulation of tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590798b82c669209feb94b0dcf2199c2
https://pubmed.ncbi.nlm.nih.gov/30976078
https://pubmed.ncbi.nlm.nih.gov/30976078