Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Radhi Anand"'
Autor:
R Marley, Steve Holt, David Goodier, Radhi Anand, Bimbi Fernando, Kevin Moore, Susan E. Davies, David Harry
Publikováno v:
Hepatology. 29:1358-1363
Chronic bile duct ligation is associated with the development of oxidant injury, biliary cirrhosis, portal hypertension, and a hyperdynamic circulation. We have previously demonstrated that the hyperdynamic circulation in the partial portal vein‐li
Publikováno v:
Kidney International. 55(1):271-277
Acute cholestasis-induced renal failure: Effects of antioxidants and ligands for the thromboxane A2 receptor.BackgroundAcute biliary obstruction is associated with the development of renal impairment and oxidative stress. The F2-isoprostanes, formed
Autor:
Chris E. Cooper, Jason D. Morrow, Victor M. Darley-Usmar, L. Jackson Roberts, Radhi Anand, David Goodier, Michael T. Wilson, Kevin P. Moore, Martine Clozel, Steve Holt, William E. Zackert, Rakesh P. Patel, Brandon J. Reeder, Dimitri A. Svistunenko
Publikováno v:
Journal of Biological Chemistry. 273:31731-31737
Muscle injury (rhabdomyolysis) and subsequent deposition of myoglobin in the kidney causes renal vasoconstriction and renal failure. We tested the hypothesis that myoglobin induces oxidant injury to the kidney and the formation of F2-isoprostanes, po
Publikováno v:
Gastroenterology. 112:208-213
BACKGROUND & AIMS: The F2-isoprostanes are a recently described class of prostaglandins formed by free radical-mediated lipid peroxidation. 8- Isoprostaglandin F2 alpha (8-iso-PGF2 alpha), an F2-isoprostane, has previously been shown to be a potent r
Publikováno v:
Journal of cardiovascular pharmacology. 44
The saphenous vein (SV) is the most commonly used conduit for coronary artery bypass surgery. However, using traditional techniques, the occlusion rate for the SV is high, with over 50% of grafts failing within 10 years. In conventional coronary arte
Publikováno v:
Angiology. 55(4)
Autologous saphenous vein is the most commonly used conduit for coronary artery bypass surgery with more than 50% grafts occluding within 10 years. In conventional preparation the vein undergoes considerable surgical trauma with damage to the outer l
Autor:
Kevin Moore, Stephen G Holt, Susan Davies, David Harry, Radhi Anand, Richard Marley, Bimbi Fernando, David Goodier
Publikováno v:
Hepatology (Baltimore, Md.). 30(5)
Sepsis is a common complication of cirrhosis with a high mortality. In this study, we have investigated some of the pathways that may be involved in tissue injury and death. Bile duct-ligated (BDL) cirrhotic and control rats were challenged with lipo
N-acetylcysteine prevents development of the hyperdynamic circulation in the portal hypertensive rat
Autor:
Roy E. Smith, D. S. Harry, Radhi Anand, Kevin Moore, George Hamilton, Bimbi Fernando, Peter Sanderson, R Marley, Steve Holt
Publikováno v:
Scopus-Elsevier
Partial portal vein ligation (PPVL) leads to the development of a hyperdynamic circulation. It is associated with elevated levels of tumor necrosis factor (TNF-alpha) and nitric oxide (NO) production, both of which can result in oxidant injury. In th
Publikováno v:
Journal of Hepatology. 34:76-77
Publikováno v:
Journal of Hepatology. 32:43