Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Radhakrishna Bettadapura"'
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 833-839 (2016)
We present the data used for an integrative approach to computational modeling of proteins with large variable domains, specifically applied in this context to model HIV Env glycoprotein gp120 in its CD4 and 17b bound state. The initial data involved
Externí odkaz:
https://doaj.org/article/468652387ab04c5b86f943c6bbca5b0e
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004289 (2015)
There continue to be increasing occurrences of both atomistic structure models in the PDB (possibly reconstructed from X-ray diffraction or NMR data), and 3D reconstructed cryo-electron microscopy (3D EM) maps (albeit at coarser resolution) of the sa
Externí odkaz:
https://doaj.org/article/1bf7024023a24a23940d9ccf523d7ac5
Autor:
Pallavi Ghana, Kathy T. H. Tzeng, Aparna Ganapathy, Ramesh Hariharan, Radhakrishna Bettadapura, Ashwini Manjunath, Joline Dalton, Vamsi Veeramachaneni, Anand Janakiraman, Shradha Saraf, Ashraf U Mannan, Shanmukh Katragadda, Niveditha Ms, Kumar B V S S P Kotha, Taryn O. Hall
Publikováno v:
Clinical chemistry. 67(8)
Background Multi–gene panel sequencing using next-generation sequencing (NGS) methods is a key tool for genomic medicine. However, with an estimated 140 000 genomic tests available, current system inefficiencies result in high genetic-testing costs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053291573bda7ce2555e61d0a2eef498
https://pubmed.ncbi.nlm.nih.gov/34120169
https://pubmed.ncbi.nlm.nih.gov/34120169
Autor:
Nishant Agrawal, Jayalakshmi Nair, Shanmukh Katragadda, Ramesh Hariharan, Radhakrishna Bettadapura, Vaijayanti Gupta, Vamsi Veeramachaneni, Ritvi K. Bagadia, Sivaraj Irusappan, Shiuli Maji, Mark W. Lingen, Vishal Rao, Muddasir Bhati, Urvashi Bahadur, Veena Ramaswamy, Nickolas Papadopoulos, Arun K Hariharan, Rifat Hasina, Chetan Bettegowda, Aarthi Ravichandran, Ashwini Shanmugam, Evgeny Izumchenko, Monica Charlotte Solomon, Netravathi Manjunath, Ashwini Manjunath
Publikováno v:
Cancer
BACKGROUND: Oral cavity squamous cell carcinoma (OCSCC) is the most common head and neck malignancy. Although the survival rate of patients with advanced-stage disease remains approximately 20% to 60%, when detected at an early stage, the survival ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d44cdae2564f7b50e9c62e716c6dbd7
https://pubmed.ncbi.nlm.nih.gov/33405231
https://pubmed.ncbi.nlm.nih.gov/33405231
Autor:
Rifat Hasina, Ramesh Hariharan, Radhakrishna Bettadapura, Arun K Hariharan, Nishant Agrawal, Ritvi K. Bagadia, Vishal Rao, Aarthi Ravichandran, Vamsi Veeramachaneni, Ashwini Shanmugam, Mark W. Lingen, Vaijayanti Gupta, Sivaraj Irusappan, Manjunath N.M.L, Urvashi Bahadur, Shiuli Maji, Evgeny Izumchenko
Publikováno v:
Journal of Clinical Oncology. 38:6562-6562
6562 Background: Oral cavity squamous cell carcinoma (OCSCC) frequently presents as clinically advanced disease with poor prognosis. When diagnosed at early stages, survival rates approach 80%, underscoring the need for validated, cost-effective dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4deab41278e2be1b2b9fe5d5c450f59
https://doi.org/10.1200/jco.2020.38.15_suppl.6562
https://doi.org/10.1200/jco.2020.38.15_suppl.6562
Publikováno v:
Structure. 23(6):1138-1149
Envelope glycoprotein gp120 of HIV-1 possesses several variable regions whose precise structure has been difficult to establish. We report a new model of gp120, in complex with antibodies CD4 and 17b, complete with its variable regions. The model was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d78b25ee8a9ee799b14d5959eb49e26
Publikováno v:
SIAM Journal on Scientific Computing. 35:B821-B845
The task of evaluating correlations is central to computational structural biology. The rigid-body correlation problem seeks the rigid-body transformation (R, t), R ∈ SO(3), t ∈ ℝ3 that maximizes the correlation between a pair of input scalar-v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6c49dd276f048867d822dd48ccdaab
https://doi.org/10.1137/120892386
https://doi.org/10.1137/120892386
Publikováno v:
Biopolymers. 97:709-731
We review tools for structure identification and model-based refinement from three-dimensional electron microscopy implemented in our in-house software package, VOLROVER 2.0. For viral density maps with icosahedral symmetry, we segment the capsid, po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1ab8c2df4533272f3736bca7dea3a99
https://doi.org/10.1002/bip.22052
https://doi.org/10.1002/bip.22052
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 11, Iss 10, p e1004289 (2015)
PLoS Computational Biology, Vol 11, Iss 10, p e1004289 (2015)
There continue to be increasing occurrences of both atomistic structure models in the PDB (possibly reconstructed from X-ray diffraction or NMR data), and 3D reconstructed cryo-electron microscopy (3D EM) maps (albeit at coarser resolution) of the sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37dbc9b8c13ee4ea4fa01c4488c87bd3
http://europepmc.org/articles/PMC4607507
http://europepmc.org/articles/PMC4607507
Autor:
Alexander Rand, Chao Peng, Alex Mollere, Radhakrishna Bettadapura, Chandrajit L. Bajaj, Na Lei
Publikováno v:
Symposium on Solid and Physical Modeling
Whereas traditional finite element methods use meshes to define domain geometry, weighted extended B-spline finite element methods rely on a weight function. A weight function is a smooth, strictly positive function which vanishes at the domain bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95978f85a2ebb55b45a9b1290191dddd
https://doi.org/10.1145/1839778.1839800
https://doi.org/10.1145/1839778.1839800