Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Radha Desai"'
Autor:
Manuela D’Eletto, Federica Rossin, Luca Occhigrossi, Maria Grazia Farrace, Danilo Faccenda, Radha Desai, Saverio Marchi, Giulia Refolo, Laura Falasca, Manuela Antonioli, Fabiola Ciccosanti, Gian Maria Fimia, Paolo Pinton, Michelangelo Campanella, Mauro Piacentini
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3573-3581.e4 (2018)
Summary: Transglutaminase type 2 (TG2) is a multifunctional enzyme that plays a key role in mitochondria homeostasis under stressful cellular conditions. TG2 interactome analysis reveals an enzyme interaction with GRP75 (glucose-regulated protein 75)
Externí odkaz:
https://doaj.org/article/a83291863d9942ff9278c205e58a4ea1
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148851
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e5149b4ca660124c320a52749d5a1a0
https://doi.org/10.1016/j.bbabio.2022.148851
https://doi.org/10.1016/j.bbabio.2022.148851
Autor:
J. Paul Chapple, Gyorgy Szabadkai, Maria Soledad Alvarez, Xia Dong, Lisa E.L. Romano, Rosella Abeti, Marta Mainenti, Robert B Bentham, Roland A. Fleck, Radha Desai, Liana Hardy, Daniel A. East, Laura Kuhlman Hussey, Anne Hamechar-Brady, Ken C. Smith, James Crosby, Valentina Zappulli, Aarti Singh, Manuel Rigon, Danilo Faccenda, Michelangelo Campanella, Gema Vizcay-Barrena, Gurtej K. Dhoot
Publikováno v:
SSRN Electronic Journal.
Mitochondria drive cellular adaptation to stress by retro-communicating with the nucleus to promote cytoprotective mechanisms. This process of inter-organelles interplay is known as the Mitochondrial Retrograde Response (MRR) and is enacted by altera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30060a6de7aa77c58d6acc1814ebb94
https://doi.org/10.2139/ssrn.3460241
https://doi.org/10.2139/ssrn.3460241
Autor:
Radha Desai, Michelangelo Campanella
Publikováno v:
Br J Pharmacol
The pharmacological targeting of cholesterol levels continues to generate interest due to the undoubted success of therapeutic agents, such as statins, in extending life expectancy by modifying the prognosis of diseases associated with the impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026733d227ef374d392b5e89ee67467d
http://hdl.handle.net/2108/265079
http://hdl.handle.net/2108/265079
Autor:
Michelangelo Campanella, Roland A. Fleck, Radha Desai, Liana Hardy, Gyorgy Szabadkai, J. Paul Chapple, Ken C. Smith, Manuel Rigon, Anne Hamechar-Brady, Valentina Zappulli, Robert B Bentham, Gema Vizcay-Barrena, Danilo Faccenda, Lisa E.L. Romano, Gurtej K. Dhoot, Marta Mainenti, Maria Soledad Alvarez, James Crosby, Arti Singh, Laura Kuhlman Hussey, Daniel A. East, Xia Dong
Mitochondria drive cellular adaptation to stress by retro-communicating with the nucleus. This process is known as Mitochondrial Retrograde Response (MRR) and is induced by mitochondrial dysfunctions which perturb cell signalling. MRR results in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::681e6be1c7ac70a67f391c10504f801c
https://doi.org/10.1101/445411
https://doi.org/10.1101/445411
Autor:
Danilo Faccenda, Luca Occhigrossi, Saverio Marchi, Paolo Pinton, Laura Falasca, Fabiola Ciccosanti, Maria Grazia Farrace, Manuela D’Eletto, Federica Rossin, Gian Maria Fimia, Radha Desai, Giulia Refolo, Manuela Antonioli, Mauro Piacentini, Michelangelo Campanella
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3573-3581.e4 (2018)
Cell Reports
Cell Reports
Summary: Transglutaminase type 2 (TG2) is a multifunctional enzyme that plays a key role in mitochondria homeostasis under stressful cellular conditions. TG2 interactome analysis reveals an enzyme interaction with GRP75 (glucose-regulated protein 75)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9acd20ff73a0567a197b6f2a9ec44e
https://pubmed.ncbi.nlm.nih.gov/30590033
https://pubmed.ncbi.nlm.nih.gov/30590033
Autor:
Radha Desai, Michelangelo Campanella
Publikováno v:
Molecular Cell
Mitochondrial protein import stress compromises functioning of the organelles, due to inadequate supply of inner mitochondrial proteins. Weidberg and Amon (2018) describe a new monitoring pathway in budding yeast, which restores mitochondrial functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445c2e4a5d44ac7299bb86b0376587ee
https://doi.org/10.1016/j.molcel.2018.06.027
https://doi.org/10.1016/j.molcel.2018.06.027
Autor:
Henry Houlden, Mara Mennuni, Gokhan Akman, Robert J. Crouch, Takehiro Yasukawa, Romina Durigon, Ilaria Dalla Rosa, Chloe F. Moss, Michael G. Hanna, Robert D S Pitceathly, Laura J. Bailey, J. Bradley Holmes, Radha Desai, Antonella Spinazzola, Ian J. Holt
The genetic information in mammalian mitochondrial DNA is densely packed; there are no introns and only one sizeable noncoding, or control, region containing key cis-elements for its replication and expression. Many molecules of mitochondrial DNA bea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0e845004fb5ab80ffc1c664268da1e
https://europepmc.org/articles/PMC4968715/
https://europepmc.org/articles/PMC4968715/
Publikováno v:
Biophysical Journal. 114:2a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cfd4fb52deb6ded685b55f83b50a58a
https://doi.org/10.1016/j.bpj.2017.11.034
https://doi.org/10.1016/j.bpj.2017.11.034
Publikováno v:
European Journal of Medicinal Chemistry. 44:5006-5011
In this work, marketed drug compounds (or known drug space) were used as a metric to test the principles of eliminating parent structures of the nitrenium ion (aryl-amine/nitro compounds) as well as sulphur and halogen containing molecules from scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e3af300eb7d5adae6b67bd5ac69750
https://doi.org/10.1016/j.ejmech.2009.08.014
https://doi.org/10.1016/j.ejmech.2009.08.014