Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Radha, L."'
Autor:
Raghavan, Srivatsan, Winter, Peter S., Navia, Andrew W., Williams, Hannah L., DenAdel, Alan, Lowder, Kristen E., Galvez-Reyes, Jennyfer, Kalekar, Radha L., Mulugeta, Nolawit, Kapner, Kevin S., Raghavan, Manisha S., Borah, Ashir A., Liu, Nuo, Väyrynen, Sara A., Costa, Andressa Dias, Ng, Raymond W.S., Wang, Junning, Hill, Emma K., Ragon, Dorisanne Y., Brais, Lauren K., Jaeger, Alex M., Spurr, Liam F., Li, Yvonne Y., Cherniack, Andrew D., Booker, Matthew A., Cohen, Elizabeth F., Tolstorukov, Michael Y., Wakiro, Isaac, Rotem, Asaf, Johnson, Bruce E., McFarland, James M., Sicinska, Ewa T., Jacks, Tyler E., Sullivan, Ryan J., Shapiro, Geoffrey I., Clancy, Thomas E., Perez, Kimberly, Rubinson, Douglas A., Ng, Kimmie, Cleary, James M., Crawford, Lorin, Manalis, Scott R., Nowak, Jonathan A., Wolpin, Brian M., Hahn, William C., Aguirre, Andrew J., Shalek, Alex K.
Publikováno v:
In Cell 9 December 2021 184(25):6119-6137
Autor:
Neggers, Jasper E., Paolella, Brenton R., Asfaw, Adhana, Rothberg, Michael V., Skipper, Thomas A., Yang, Annan, Kalekar, Radha L., Krill-Burger, John M., Dharia, Neekesh V., Kugener, Guillaume, Kalfon, Jérémie, Yuan, Chen, Dumont, Nancy, Gonzalez, Alfredo, Abdusamad, Mai, Li, Yvonne Y., Spurr, Liam F., Wu, Westley W., Durbin, Adam D., Wolpin, Brian M., Piccioni, Federica, Root, David E., Boehm, Jesse S., Cherniack, Andrew D., Tsherniak, Aviad, Hong, Andrew L., Hahn, William C., Stegmaier, Kimberly, Golub, Todd R., Vazquez, Francisca, Aguirre, Andrew J.
Publikováno v:
In Cell Reports 15 December 2020 33(11)
Autor:
Jasper E. Neggers, Brenton R. Paolella, Adhana Asfaw, Michael V. Rothberg, Thomas A. Skipper, Annan Yang, Radha L. Kalekar, John M. Krill-Burger, Neekesh V. Dharia, Guillaume Kugener, Jérémie Kalfon, Chen Yuan, Nancy Dumont, Alfredo Gonzalez, Mai Abdusamad, Yvonne Y. Li, Liam F. Spurr, Westley W. Wu, Adam D. Durbin, Brian M. Wolpin, Federica Piccioni, David E. Root, Jesse S. Boehm, Andrew D. Cherniack, Aviad Tsherniak, Andrew L. Hong, William C. Hahn, Kimberly Stegmaier, Todd R. Golub, Francisca Vazquez, Andrew J. Aguirre
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109367- (2021)
Externí odkaz:
https://doaj.org/article/ac506d36e0fc45f58afd5108c6469b14
Publikováno v:
Journal of Engineering Education Transformations; Apr2024, Vol. 37 Issue 4, p29-35, 7p
Autor:
Jasper E. Neggers, Brenton R. Paolella, Adhana Asfaw, Michael V. Rothberg, Thomas A. Skipper, Annan Yang, Radha L. Kalekar, John M. Krill-Burger, Neekesh V. Dharia, Guillaume Kugener, Jérémie Kalfon, Chen Yuan, Nancy Dumont, Alfredo Gonzalez, Mai Abdusamad, Yvonne Y. Li, Liam F. Spurr, Westley W. Wu, Adam D. Durbin, Brian M. Wolpin, Federica Piccioni, David E. Root, Jesse S. Boehm, Andrew D. Cherniack, Aviad Tsherniak, Andrew L. Hong, William C. Hahn, Kimberly Stegmaier, Todd R. Golub, Francisca Vazquez, Andrew J. Aguirre
Publikováno v:
Cell Reports, Vol 33, Iss 11, Pp 108493- (2020)
Summary: Few therapies target the loss of tumor suppressor genes in cancer. We examine CRISPR-SpCas9 and RNA-interference loss-of-function screens to identify new therapeutic targets associated with genomic loss of tumor suppressor genes. The endosom
Externí odkaz:
https://doaj.org/article/8d45f5f857914e55852e4f26974a4071
Akademický článek
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Autor:
Brian M. Wolpin, Jonathan A. Nowak, Andrew J. Aguirre, Alex K. Shalek, William C. Hahn, Aram F. Hezel, Albert C. Koong, Daniel T. Chang, Richard F. Dunne, David C. Linehan, Margaret M. Kozak, Emma R. Hill, Lauren K. Brais, Joseph D. Mancias, Jiping Wang, Thomas E. Clancy, James M. Cleary, Kimberly Perez, Harshabad Singh, Douglas A. Rubinson, Vicente Morales-Oyarvide, Dalia Elganainy, Mai Chan Lau, Kristen E. Lowder, Radha L. Kalekar, Timothy L. Bosse, Annan Yang, Junning Wang, Andrew W. Navia, Chen Yuan, Juha P. Väyrynen, Sara A. Väyrynen, Scott P. Ginebaugh, Kevin S. Kapner, Peter S. Winter, Srivatsan Raghavan, Jinming Zhang, Andressa Dias Costa, Hannah L. Williams
Pancreatic ductal adenocarcinoma (PDAC) has been classified into classical and basal-like transcriptional subtypes by bulk RNA measurements. However, recent work has uncovered greater complexity to transcriptional subtypes than was initially apprecia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58901a59881a291461b659642ab759fd
https://doi.org/10.1158/0008-5472.c.6514341.v1
https://doi.org/10.1158/0008-5472.c.6514341.v1
Autor:
Brian M. Wolpin, Jonathan A. Nowak, Andrew J. Aguirre, Alex K. Shalek, William C. Hahn, Aram F. Hezel, Albert C. Koong, Daniel T. Chang, Richard F. Dunne, David C. Linehan, Margaret M. Kozak, Emma R. Hill, Lauren K. Brais, Joseph D. Mancias, Jiping Wang, Thomas E. Clancy, James M. Cleary, Kimberly Perez, Harshabad Singh, Douglas A. Rubinson, Vicente Morales-Oyarvide, Dalia Elganainy, Mai Chan Lau, Kristen E. Lowder, Radha L. Kalekar, Timothy L. Bosse, Annan Yang, Junning Wang, Andrew W. Navia, Chen Yuan, Juha P. Väyrynen, Sara A. Väyrynen, Scott P. Ginebaugh, Kevin S. Kapner, Peter S. Winter, Srivatsan Raghavan, Jinming Zhang, Andressa Dias Costa, Hannah L. Williams
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05b8ab2de7cfe7f7ab46e4e9b09fa895
https://doi.org/10.1158/0008-5472.22433331.v1
https://doi.org/10.1158/0008-5472.22433331.v1
Autor:
Hannah L. Williams, Andressa Dias Costa, Jinming Zhang, Srivatsan Raghavan, Peter S. Winter, Kevin S. Kapner, Scott P. Ginebaugh, Sara A. Väyrynen, Juha P. Väyrynen, Chen Yuan, Andrew W. Navia, Junning Wang, Annan Yang, Timothy L. Bosse, Radha L. Kalekar, Kristen E. Lowder, Mai Chan Lau, Dalia Elganainy, Vicente Morales-Oyarvide, Douglas A. Rubinson, Harshabad Singh, Kimberly Perez, James M. Cleary, Thomas E. Clancy, Jiping Wang, Joseph D. Mancias, Lauren K. Brais, Emma R. Hill, Margaret M. Kozak, David C. Linehan, Richard F. Dunne, Daniel T. Chang, Albert C. Koong, Aram F. Hezel, William C. Hahn, Alex K. Shalek, Andrew J. Aguirre, Jonathan A. Nowak, Brian M. Wolpin
Publikováno v:
Cancer research.
Pancreatic ductal adenocarcinoma (PDAC) has been classified into classical and basal-like transcriptional subtypes by bulk RNA measurements. However, recent work has uncovered greater complexity to transcriptional subtypes than was initially apprecia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5578179943efe3fd30fd9632eb9d837d
https://pubmed.ncbi.nlm.nih.gov/36459568
https://pubmed.ncbi.nlm.nih.gov/36459568
Autor:
Jinhua Wang, Senthil Muthaswamy, Kevin M. Haigis, Rita Sulahian, Kenneth D. Westover, Emily J. Poulin, Ryoma Ohi, Sergio Espinosa, Shuning He, Taebo Sim, Lianbo Li, Miljan Kuljanin, Nathanael S. Gray, Yan Liu, Nam Doo Kim, Joseph D. Mancias, Ling Huang, Brian M. Wolpin, Charles Y. Lin, Andrew J. Aguirre, Srivatsan Raghavan, Nora Diéguez-Martínez, Radha L. Kalekar, Jost Vrabic Koren, Zeng Zhiyang, Fleur M. Ferguson, James D Vasta, Behnam Nabet, William C. Hahn, Raymond W.S. Ng, Cesear Corona, Wayne Harshbarger, Alan L. Leggett, Matthew B. Robers, A. Thomas Look, Jose M. Lizcano, Annan Yang
Publikováno v:
Nature chemical biology
Doublecortin like kinase 1 (DCLK1) is an understudied kinase that is upregulated in a wide range of cancers, including pancreatic ductal adenocarcinoma (PDAC). However, little is known about its potential as a therapeutic target. We used chemoproteom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0e3c79de5a15f9fac24f15a81dc963
https://doi.org/10.1038/s41589-020-0506-0
https://doi.org/10.1038/s41589-020-0506-0