Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Radene Showalter"'
Autor:
Gregory T. Everson, Radene Showalter, Ann Scherzinger, Roshan Sherstha, Carol McKinley, Paul Russ, Teresa Bronner
Publikováno v:
Hepatology. 26:1282-1286
The goal of this study was to determine whether use of postmenopausal estrogen (Premarin, Wyeth-Ayerst, Philadelphia, PA) in women with autosomal dominant polycystic kidney disease (ADPKD) increases liver, hepatic cyst, or kidney volume. We also dete
Autor:
Carol McKinley, Roshan Shrestha, Keith Wilner, Luis Marsano, Gregory T. Everson, Radene Showalter, Beverly Vivian
Publikováno v:
Liver Transplantation and Surgery. 3:166-173
Some patients with early-stage cirrhosis preserve hepatic function, whereas others have little hepatic reserve and rapidly deteriorate. The aim of this study was to use quantitative tests of liver function (QLFTs) to define the degree of functional h
Autor:
Carol McKinley, Louise Cockey, Daniel G Pace, Roberto Guerciolini, Juergen Häeussler, Jianguo Zhi, Thomas Trouillot, Gregory T. Everson, Radene Showalter
Publikováno v:
The American journal of gastroenterology. 96(6)
OBJECTIVES: Orlistat, an intestinal lipase inhibitor, has recently been approved by the US Food and Drug Administration for treatment of obesity. The effects of orlistat on hepatobiliary function have not been previously defined. A 4 wk study was per
Autor:
Janette D. Durham, David A. Kumpe, William G. Rector, BM Bilir, Roshan Shrestha, Gregory T. Everson, Radene Showalter, G DeRoche
Publikováno v:
Hepatology. 22:A165
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 1, Pp 204-210 (1982)
A method for the extraction of bile acids from serum is described that enables the stable isotopic content of chenodeoxycholic acid and cholic acid to be determined accurately to levels as low as the natural 13C abundance. The method uses Sep-Pak C18
Publikováno v:
Biochemical Journal. 174:45-51
Rats treated with ethynyloestradiol have marked hypolipidaemia: serum cholesterol is decreased to 5%, triacylglycerol to 10% and phospholipid to 70% of control concentrations. Loss of serum cholesterol follows an exponential decay, with a half-life o
Publikováno v:
Biochemistry. 25:1632-1636
Rats treated with ethinylestradiol (5 mg kg-1 day-1 for 5 days) secrete de novo synthesized bile acids at a markedly reduced rate (-57%). Administration of the nonionic detergent Triton WR-1339 to estradiol-treated rats rapidly restored the rate of s
Publikováno v:
Gastroenterology. 69:483-491
In vitro studies have shown that some bile salts inhibit the growth of intestinal bacteria. We investigated the possibility that bile salts might have a similar action in vivo in the ileum by performing serial anaerobic cultures and bile salt analyse
Autor:
Gregory T. Everson, Radene Showalter, B DeMark, P Szczepanik-van Leeuwen, W. Erfling, Fred Kern, P. D. Klein, Carol McKinley, Dan Z. Braverman
Publikováno v:
Journal of Clinical Investigation. 68:1229-1242
To study the events that might lead to an increased risk of cholesterol gallstones, we examined biliary lipid composition and secretion and bile acid composition and kinetics at different stages of pregnancy or ovulation in young, nonobese, healthy w
Autor:
Francis R. Simon, Fred Kern, Michael Sinensky, Eileen Sutherland, Roger A. Davis, Radene Showalter
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 75(9)
Administration of the synthetic estrogen ethinyl estradiol (17α-ethinyl-1,3,5-estratriene-3,17β-diol) decreases hepatic Na + ,K + -ATPase (ATP phosphohydrolase; EC 3.6.1.3) activity and bile flow to 50% and alters the composition and structure of s