Zobrazeno 1 - 10
of 1 914
pro vyhledávání: '"Rademakers, P."'
Autor:
Gao, Shan, Albu, Elena, Putter, Hein, Stijnen, Pieter, Rademakers, Frank, Cossey, Veerle, Debaveye, Yves, Janssens, Christel, Van Calster, Ben, Wynants, Laure
Objective Hospitals register information in the electronic health records (EHR) continuously until discharge or death. As such, there is no censoring for in-hospital outcomes. We aimed to compare different dynamic regression modeling approaches to pr
Externí odkaz:
http://arxiv.org/abs/2405.01986
Autor:
Albu, Elena, Gao, Shan, Stijnen, Pieter, Rademakers, Frank, Janssens, Christel, Cossey, Veerle, Debaveye, Yves, Wynants, Laure, Van Calster, Ben
Prognostic outcomes related to hospital admissions typically do not suffer from censoring, and can be modeled either categorically or as time-to-event. Competing events are common but often ignored. We compared the performance of random forest (RF) m
Externí odkaz:
http://arxiv.org/abs/2404.16127
Autor:
Momo, Lyse Naomi Wamba, Moorosi, Nyalleng, Nsoesie, Elaine O., Rademakers, Frank, De Moor, Bart
Inpatient length of stay (LoS) is an important managerial metric which if known in advance can be used to efficiently plan admissions, allocate resources and improve care. Using historical patient data and machine learning techniques, LoS prediction
Externí odkaz:
http://arxiv.org/abs/2306.16823
Autor:
Kurt Farrell, Jack Humphrey, Timothy Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa, Vishakha Patil, Wan-Ping Lee, Amanda B. Kuzma, Otto Valladares, Laura B. Cantwell, Hui Wang, Ashvin Ravi, Claudia De Sanctis, Natalia Han, Thomas D. Christie, Robina Afzal, Shrishtee Kandoi, Kristen Whitney, Margaret M. Krassner, Hadley Ressler, SoongHo Kim, Diana Dangoor, Megan A. Iida, Alicia Casella, Ruth H. Walker, Melissa J. Nirenberg, Alan E. Renton, Bergan Babrowicz, Giovanni Coppola, Towfique Raj, Günter U. Höglinger, Ulrich Müller, Lawrence I. Golbe, Huw R. Morris, John Hardy, Tamas Revesz, Tom T. Warner, Zane Jaunmuktane, Kin Y. Mok, Rosa Rademakers, Dennis W. Dickson, Owen A. Ross, Li-San Wang, Alison Goate, Gerard Schellenberg, Daniel H. Geschwind, PSP Genetics Study Group, John F. Crary, Adam Naj
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Progressive supranuclear palsy (PSP), a rare Parkinsonian disorder, is characterized by problems with movement, balance, and cognition. PSP differs from Alzheimer’s disease (AD) and other diseases, displaying abnormal microtubule-associate
Externí odkaz:
https://doaj.org/article/07eaa87799dd4d0f92bc88b303182da0
Autor:
Hui Wang, Timothy S. Chang, Beth A. Dombroski, Po-Liang Cheng, Vishakha Patil, Leopoldo Valiente-Banuet, Kurt Farrell, Catriona Mclean, Laura Molina-Porcel, Alex Rajput, Peter Paul De Deyn, Nathalie Le Bastard, Marla Gearing, Laura Donker Kaat, John C. Van Swieten, Elise Dopper, Bernardino F. Ghetti, Kathy L. Newell, Claire Troakes, Justo G. de Yébenes, Alberto Rábano-Gutierrez, Tina Meller, Wolfgang H. Oertel, Gesine Respondek, Maria Stamelou, Thomas Arzberger, Sigrun Roeber, Ulrich Müller, Franziska Hopfner, Pau Pastor, Alexis Brice, Alexandra Durr, Isabelle Le Ber, Thomas G. Beach, Geidy E. Serrano, Lili-Naz Hazrati, Irene Litvan, Rosa Rademakers, Owen A. Ross, Douglas Galasko, Adam L. Boxer, Bruce L. Miller, Willian W. Seeley, Vivanna M. Van Deerlin, Edward B. Lee, Charles L. White, Huw Morris, Rohan de Silva, John F. Crary, Alison M. Goate, Jeffrey S. Friedman, Yuk Yee Leung, Giovanni Coppola, Adam C. Naj, Li-San Wang, P. S. P. genetics study group, Clifton Dalgard, Dennis W. Dickson, Günter U. Höglinger, Gerard D. Schellenberg, Daniel H. Geschwind, Wan-Ping Lee
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease characterized by the accumulation of aggregated tau proteins in astrocytes, neurons, and oligodendrocytes. Previous genome-wide association studies for PSP w
Externí odkaz:
https://doaj.org/article/855cdef1a9b046af9ac1a7a118950c99
Agent-based modeling plays an essential role in gaining insights into biology, sociology, economics, and other fields. However, many existing agent-based simulation platforms are not suitable for large-scale studies due to the low performance of the
Externí odkaz:
http://arxiv.org/abs/2301.06984
Autor:
S. Borrego Écija, J. Juncà Parella, M. Vandebergh, A. Pérez Millán, M. Balasa, A. Lladó, A. Bouzigues, L. Rusell, P. Foster, E. Ferry Bolder, J. van Swieten, L. Jiskoot, H. Seelaar, R. Laforce, C. Graff, D. Galimberti, R. Vandenberghe, A. de Mendonça, P. Tiraboschi, I. Santana, A. Gerhard, J. Levin, S. Sorbi, M. Otto, F. Pasquier, S. Ducharme, C. Butler, I. Le Ber, E. Finger, M. Tartaglia, M. Masellis, J. Rowe, M. Synofzik, F. Moreno, B. Borroni, R. Rademakers, J. Rohrer, R. Sánchez del Valle
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 17- (2024)
Externí odkaz:
https://doaj.org/article/88d276e79ab34eaa9d2fbde005e8d5b9
20072. FENOTIPO CLINICOPATOLÓGICO DE LA DEMENCIA FRONTOTEMPORAL CAUSADA POR LA MUTACIÓN P.P397S MAPT
Autor:
S. Borrego Écija, I. Bartolomé, I. Aldecoa, J. Juncà Parella, L. Molina Porcel, A. Antonell, M. Balasa, A. Lladó, A. Herrero, A. Villarejo, C. Alquezar, E. Gelpi, R. Rademakers, R. Sánchez del Valle
Publikováno v:
Neurology Perspectives, Vol 4, Iss , Pp 18- (2024)
Externí odkaz:
https://doaj.org/article/41adb16239b445aea01a74cb540dd76c
Autor:
Michael Benatar, Eric A. Macklin, Andrea Malaspina, Mary-Louise Rogers, Eran Hornstein, Vittoria Lombardi, Danielle Renfrey, Stephanie Shepheard, Iddo Magen, Yahel Cohen, Volkan Granit, Jeffrey M. Statland, Jeannine M. Heckmann, Rosa Rademakers, Caroline A. McHutchison, Leonard Petrucelli, Corey T. McMillan, Joanne Wuu, Lauren Elman, John Ravits, Jonathan Katz, Jaya Trivedi, Andrea Swenson, Ted M. Burns, James Caress, Carlayne Jackson, Samuel Maiser, Erik P. Pioro, Yuen So
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105323- (2024)
Summary: Background: With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and
Externí odkaz:
https://doaj.org/article/e1d4a293db1a412aa52ac92f571d2d19
Autor:
Merel Engelaar, Nanne Bos, Femke van Schelven, Nora Lorenzo i Sunyer, Norbert Couespel, Giovanni Apolone, Cinzia Brunelli, Augusto Caraceni, Montse Ferrer, Mogens Groenvold, Stein Kaasa, Gennaro Ciliberto, Claudio Lombardo, Ricardo Pietrobon, Gabriella Pravettoni, Aude Sirven, Hugo Vachon, Alexandra Gilbert, Jany Rademakers
Publikováno v:
Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Patient and public involvement (PPI) has become an essential part of health research. There is a need for genuine involvement in order to ensure that research is relevant to patients. This can then improve the quality, relevance,
Externí odkaz:
https://doaj.org/article/c82f8e8f4a924cbcb620eb4f9698a7d3