Chronic hyperactivation of midbrain dopamine neurons causes preferential dopamine neuron degeneration.

Autor: Rademacher K; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Graduate Program in Neuroscience, University of California San Francisco, San Francisco , CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Doric Z; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Graduate Program in Neuroscience, University of California San Francisco, San Francisco , CA., Haddad D; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA., Mamaligas A; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA., Liao SC; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; Department of Nutritional Sciences & Toxicology, University of California Berkeley, Berkeley, CA.; Endocrinology Graduate Program, University of California Berkeley, Berkeley, CA., Creed RB; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; UCSF Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA., Kano K; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Chatterton Z; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; Brain and Mind Centre, Faculty of Medicine and Health, School of Medical Sciences, University of Sydney, Sydney, Australia., Fu Y; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; Brain and Mind Centre, Faculty of Medicine and Health, School of Medical Sciences, University of Sydney, Sydney, Australia., Garcia JH; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; School of Medicine, University of California, San Francisco, California, USA., Vance V; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; College of Science, Northeastern University, Boston, MA., Sei Y; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD., Kreitzer A; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Graduate Program in Neuroscience, University of California San Francisco, San Francisco , CA.; UCSF Department of Physiology, University of California San Francisco, CA., Halliday GM; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; Brain and Mind Centre, Faculty of Medicine and Health, School of Medical Sciences, University of Sydney, Sydney, Australia., Nelson AB; Graduate Program in Neuroscience, University of California San Francisco, San Francisco , CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; UCSF Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA., Margolis EB; Graduate Program in Neuroscience, University of California San Francisco, San Francisco , CA.; UCSF Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA., Nakamura K; Gladstone Institute for Neurological Disease, Gladstone Institutes, San Francisco, CA.; Graduate Program in Neuroscience, University of California San Francisco, San Francisco , CA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD.; UCSF Weill Institute for Neurosciences, Department of Neurology, University of California, San Francisco, CA.; Graduate Program in Biomedical Sciences, University of California San Francisco, San Francisco.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 13. Date of Electronic Publication: 2024 May 13.