Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Radan, Brůha"'
Autor:
Jaroslav Macášek, Barbora Staňková, Aleš Žák, Markéta Růžičková, Radan Brůha, Simona Kutová, Marek Vecka, Miroslav Zeman
Publikováno v:
Nutrition & Diabetes, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Background The role of fatty acids (FA) in the pathogenesis of insulin resistance and hyperlipidemia is a subject of intensive research. Several recent works have suggested cis-vaccenic acid (cVA) in plasma lipid compartments, especially in
Externí odkaz:
https://doaj.org/article/e9841215979f4395abaf10563d377d1f
Autor:
Václav Šmíd, Karel Dvořák, Petr Šedivý, Vít Kosek, Martin Leníček, Monika Dezortová, Jana Hajšlová, Milan Hájek, Libor Vítek, Kamila Bechyňská, Radan Brůha
Publikováno v:
Hepatology Communications, Vol 6, Iss 6, Pp 1336-1349 (2022)
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. n‐3 polyunsaturated fatty acids (n‐3‐PUFAs) have been reported to ameliorate the progression of NAFLD in experimental studies; however, clinical trials have yiel
Externí odkaz:
https://doaj.org/article/ac9851f6a8084a2786db1dc1a9a79346
Autor:
Martin Leníček, Václav Šmíd, Petr Pajer, Anna Nazarova, Karel Dvořák, Iva Subhanová, Radan Brůha, Libor Vítek
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract The patatin-like phospholipase domain containing 3 (PNPLA3) gene (viz. its I148M variant) is one of the key players in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). We have identified a novel insertion/deletion variant of 111
Externí odkaz:
https://doaj.org/article/5581a4fd50f34deaa352f9233e04797f
Autor:
Kateřina Žížalová, Barbora Nováková, Marek Vecka, Jaromír Petrtýl, Věra Lánská, Květa Pelinková, Václav Šmíd, Radan Brůha, Libor Vítek, Martin Leníček
Publikováno v:
Liver International. 43:888-895
Severity of portal hypertension is usually quantified by measuring the hepatic venous pressure gradient (HVPG). However, due to its invasiveness, alternative markers are being sought. Bile acids (BA), being synthesized, metabolized, and transported b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27355f6964dc37536ff2f3a0d8c4808e
https://doi.org/10.1111/liv.15481
https://doi.org/10.1111/liv.15481
Autor:
Jaromír Petrtýl, Karel Dvořák, Jan Stříteský, Martin Leníček, Alena Jirásková, Václav Šmíd, Martin Haluzík, Radan Brůha, Libor Vítek
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 2000 (2021)
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disorder worldwide. The aim of our study was to assess the role of bilirubin, and the heme oxygenase 1 (HMOX1) and bilirubin UDP-glucuronosyl transferase (UGT1A1) promoter
Externí odkaz:
https://doaj.org/article/033bb2e8916540f4bfa7ade8cf3b9de0
Autor:
Berivan Gurbuz, Nurdan Guldiken, Philipp Reuken, Lei Fu, Katharina Remih, Christian Preisinger, Radan Brůha, Martin Leníček, Jaromír Petrtýl, Johanna Reissing, Mahmoud Aly, Malin Fromme, Biaohuan Zhou, Isabel Karkossa, Kristin Schubert, Martin von Bergen, Andreas Stallmach, Tony Bruns, Pavel Strnad
Publikováno v:
Hepatology international 17(3), 698-708 (2023). doi:10.1007/s12072-022-10473-x
Hepatology international 17(3), 698-708 (2023). doi:10.1007/s12072-022-10473-x
Published by Springer, Heidelberg
Published by Springer, Heidelberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fe41aca814219d5d452f4d999a6550
Autor:
Jiří, Hlušička, Radan, Brůha
Publikováno v:
Casopis lekaru ceskych. 161(2)
The Czech Republic is still one of the European countries with above-average alcohol consumption. Excessive consumption has a dual effect - it affects the soul and body, leads to the development of alcohol dependence, withdrawal symptoms, psychosocia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31fff3ad4444e2df9ee962abe61e544d
https://pubmed.ncbi.nlm.nih.gov/35728964
https://pubmed.ncbi.nlm.nih.gov/35728964
Publikováno v:
Casopis lekaru ceskych. 161(2)
Statins are widely accepted hypolipidemics that work by inhibiting hydroxymethylglutaryl coenzyme A reductase and thereby inhibiting cholesterol synthesis. They significantly reduce cardiovascular risk. Their use could be associated with side effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d750fada6988389c18bb395b90966417
https://pubmed.ncbi.nlm.nih.gov/35728963
https://pubmed.ncbi.nlm.nih.gov/35728963
Publikováno v:
Vnitrni lekarstvi. 67(E-5)
Cil studie: Charakterizovat pacienty s covidem-19 hospitalizovane na nasi JIP, zjistit jejich mortalitu a výskyt komorbidit považovaných za rizikove faktory pro těžký průběh nemoci. Metodika: Retrospektivni observacni studie na JIP vyssiho ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07cf93bc534077c0cd940e3597fed98
https://pubmed.ncbi.nlm.nih.gov/35459389
https://pubmed.ncbi.nlm.nih.gov/35459389
Autor:
Petr Urbánek, Martin Leníček, Lucie Muchová, Iva Subhanová, Ladislav Dušek, Nikola Kaspříkova, Petr Hrabal, Radan Brůha, Libor Vítek
Publikováno v:
Annals of Hepatology, Vol 10, Iss 4, Pp 445-451 (2011)
Background. Heme oxygenase-1 (HMOX1) and bilirubin UDP-glucuronosyltransferase (UGT1A1), both enzymes involved in bilirubin homeostasis, play an important role inoxidative stress defense.Objective. To assess the effect of promotervariations of HMOX1
Externí odkaz:
https://doaj.org/article/59f7a99e9d904c218f305fb439efa650