Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Radaduen, Tinmanee"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 146:29-36
Gabapentin was used as a model pharmaceutical compound with susceptibility to polymorphic transformation as a function of environmental and mechanical stress. The utility of 13 C CP/MAS NMR and XRPD as stability-indicating methods to quantify polymor
Publikováno v:
Pharmaceutical Research. 35
The purpose of the research described herein was to develop a kinetic model for quantifying the effects of conditional and compositional variations on non-covalent polymorphic and covalent chemical transformations of gabapentin. Kinetic models that d
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 146
Gabapentin was used as a model pharmaceutical compound with susceptibility to polymorphic transformation as a function of environmental and mechanical stress. The utility of
Publikováno v:
Journal of Pharmaceutical Sciences. 101:2123-2133
Gabapentin degrades directly to gabapentin-lactam (gaba-L) in the solid state. The objective of this study was to formulate a drug degradation model that accounted for the environmental storage conditions and mechanical stress (prior to storage) on l