Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rada Savic"'
Publikováno v:
Sensors, Vol 24, Iss 15, p 5024 (2024)
Poor pain alleviation remains a problem following orthopedic surgery, leading to prolonged recovery time, increased morbidity, and prolonged opioid use after hospitalization. Wearable device data, collected during postsurgical recovery, may help amel
Externí odkaz:
https://doaj.org/article/0dd458b16e5648f0b592f452b3caf2af
Autor:
Nicholas Winters, Mireille E Schnitzer, Jonathon R Campbell, Susannah Ripley, Carla Winston, Rada Savic, Nafees Ahmad, Gregory Bisson, Keertan Dheda, Ali Esmail, Medea Gegia, Ignacio Monedero, Margareth Pretti Dalcolmo, Denise Rodrigues, Rupak Singla, Jae-Joon Yim, Dick Menzies
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292106 (2023)
ObjectiveStudying treatment duration for rifampicin-resistant and multidrug-resistant tuberculosis (MDR/RR-TB) using observational data is methodologically challenging. We aim to present a hypothesis generating approach to identify factors associated
Externí odkaz:
https://doaj.org/article/533a6bd4de0b4a638caafb4d9f02d24a
Autor:
Jordan T. Brooks, Belen P. Solans, Ying Lu, Sandhya Kharbanda, Christopher C. Dvorak, Nahal Lalefar, Susie Long, Ashish O. Gupta, Biljana Horn, Jatinder K. Lamba, Liusheng Huang, Beth Apsel-Winger, Ron J. Keizer, Rada Savic, Janel Long-Boyle
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2462 (2022)
Fludarabine is a nucleoside analog with antileukemic and immunosuppressive activity commonly used in allogeneic hematopoietic cell transplantation (HCT). Several fludarabine population pharmacokinetic (popPK) and pharmacodynamic models have been publ
Externí odkaz:
https://doaj.org/article/d21a0c32b48140698c426dacb4569d19
Autor:
Susan J. Knox, Priya Jayachandran, Christine A. Keeling, Kathryn J. Stevens, Navjot Sandhu, Stacy Leanne Stamps-DeAnda, Rada Savic, Lei Shura, Mark K. Buyyounouski, Kevin Grimes
Publikováno v:
Translational Oncology, Vol 12, Iss 11, Pp 1525-1531 (2019)
In preclinical studies, selenite had single agent activity and radiosensitized tumors in vivo. Here we report results from a Phase 1 trial in 15 patients with metastatic cancer treated with selenite (5.5 to 49.5 mg) orally as a single dose 2 hours be
Externí odkaz:
https://doaj.org/article/08b01bdd9c0e418f94f6a4dfc4e92a99
Publikováno v:
PLoS Medicine, Vol 16, Iss 12, p e1002884 (2019)
Andrew Vernon and co-authors discuss adherence to therapy and its measurement in tuberculosis treatment trials.
Externí odkaz:
https://doaj.org/article/d86b9660cd654ea8b86739b70f0d2b99
Autor:
Won-ho Kang, Jae-yeon Lee, Jung-woo Chae, Kyeong-Ryoon Lee, In-hwan Baek, Min-Soo Kim, Hyun-moon Back, Sangkeun Jung, Craig Shaffer, Rada Savic, Hwi-yeol Yun
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 114 (2021)
Sample sizes for single-period clinical trials, including pharmacokinetic studies, are statistically determined by within-subject variability (WSV). However, it is difficult to determine WSV without replicate-designed clinical trial data, and statist
Externí odkaz:
https://doaj.org/article/8616252597634ab59a550a02c6d48520
Autor:
Julie Bertrand, Aurélie Barrail-Tran, Lucie Fayette, Rada Savic, Cécile Goujard, Elina Teicher, Caroline Barau, Alain Pruvost, Anne-Marie Taburet, France Mentré, Céline Verstuyft, A. Barrail-Tran, A. Brunet, M.-J. Commoy, S. Couffin-Cadiergues, D. Descamps, X. Duval, C. Goujard, C. Le Guellec, F. Mentré, G. Nembot, A.-M. Taburet, B. Vrijens, •• Ajana, •• Aissi, •• Baclet, •• Besnier, •• Bollens, •• Boulanger, •• Brochier, •• Brunet, •• Chaix, •• Ciuchete, •• Ghosn, •• Duval, •• Ferret, •• Gaubin, •• Goujard, •• Girard, •• Kouadio, •• Lupin, •• Parienti, •• Parrinello, •• Poinçon de la Blanchardière, •• May, •• Marien, •• Medintzeff, •• Metivier, •• Mole, •• Molina, •• Nau, •• Ouazene, •• Pintado, •• Quertainmont, •• Ramani, •• Rami, •• Sellier, •• Simon, •• Talbi, •• Thoirain, •• Verdon, •• Trépo, •• Wassoumbou, •• Yazdanpanah, •• Barrail-Tran, •• Gagneux, •• Delhotal, •• Hoizey, •• Houdret, •• Leguellec, •• Peytavin, •• Poirier, •• Sauvageon, •• Taburet, •• André, •• Soulié, •• Calvez, •• Morand-Joubert, •• Harchi, •• Bocket, •• Mourez, •• Palmer, •• Pallier, •• Deschamps, •• Mazeron, •• Bolmann, •• Storto, •• Thanh Thuy, G. Unal, X. Panhard, R. Savic
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Tenofovir (TFV) and emtricitabine (FTC) are part of the recommended highly active antiretroviral therapy (ART). Both molecules show a large interindividual pharmacokinetic (PK) variability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79edc80bf1b79fa9ec9c15a7af7db223
https://doi.org/10.1128/aac.02339-18
https://doi.org/10.1128/aac.02339-18
Despite known treatments, tuberculosis (TB) remains the world’s top infectious killer, highlighting the pressing need for new drug regimens. To prioritize the most efficacious drugs for clinical testing, we previously developed a PK-PD translationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f9906076938170fbb134d621318cae
https://doi.org/10.1101/2023.02.16.528876
https://doi.org/10.1101/2023.02.16.528876
