Linking the genotypes and phenotypes of cancer cells in heterogenous populations via real-time optical tagging and image analysis.

Autor: You L; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Su PR; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Department of Chemistry, National Taiwan University, Taipei, Taiwan., Betjes M; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Rad RG; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Chou TC; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Beerens C; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., van Oosten E; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Leufkens F; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Gasecka P; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands.; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands., Muraro M; Single Cell Discoveries, Utrecht, The Netherlands., van Tol R; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands., van Steenderen D; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Farooq S; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Hardillo JAU; Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands., de Jong RB; Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands., Brinks D; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands. d.brinks@tudelft.nl.; Department of Imaging Physics, Delft University of Technology, Delft, The Netherlands. d.brinks@tudelft.nl., Chien MP; Department of Molecular Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands. m.p.chien@erasmusmc.nl.; Erasmus MC Cancer Institute, Rotterdam, The Netherlands. m.p.chien@erasmusmc.nl.; Oncode Institute, Utrecht, The Netherlands. m.p.chien@erasmusmc.nl.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2022 May; Vol. 6 (5), pp. 667-675. Date of Electronic Publication: 2022 Mar 17.