A multiprotein supercomplex controlling oncogenic signalling in lymphoma

Autor: Maryknoll Palisoc, Lu Chen, Craig J. Thomas, Michele Ceribelli, Fausto J. Rodriguez, George E. Wright, Yanlong Ji, Jan Delabie, Masao Nakagawa, Ryan M. Young, Wing C. Chan, James D. Phelan, Randy D. Gascoyne, Stephen M. Hewitt, Theresa Davies-Hill, Sandrine Roulland, Dan E. Webster, Monica Kasbekar, Fayez Estephan, Weihong Xu, German Ott, Andreas Rosenwald, Elias Campo, Thomas Oellerich, Emmanuel Bachy, Xin Yu, Lisa M. Rimsza, Hong Zhao, Louis M. Staudt, Roland Schmitz, Michael J. Kruhlak, Stefania Pittaluga, Yandan Yang, Elaine S. Jaffe, Racquel R. Valadez, Arthur L. Shaffer, Matthias Holdhoff, Da-Wei Huang, Wyndham H. Wilson, James Q. Wang

Publikováno v: Nature
Nature, 2018, 560 (7718), pp.387+. ⟨10.1038/s41586-018-0290-0⟩
Nature, Nature Publishing Group, 2018, 560 (7718), pp.387+. ⟨10.1038/s41586-018-0290-0⟩

B cell receptor (BCR) signalling has emerged as a therapeutic target in B cell lymphomas, but inhibiting this pathway in diffuse large B cell lymphoma (DLBCL) has benefited only a subset of patients1. Gene expression profiling identified two major su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd776a37748f905f88418460b800dcd3
https://hal.science/hal-02117984