Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rachna Rastogi"'
Autor:
Rachna, Rastogi
Publikováno v:
Journal of cosmetic science. 72(1)
Alkyl polyglucosides (APGs) belong to the class of green or natural surfactants synthesized from fatty acids and sugars. Growing concerns on toxicity of sulfates and ethoxylates has led to their popularity in personal and home care products. Increasi
Autor:
Igal Szleifer, Patrick F. Kiser, David C. Malaspina, Rachna Rastogi, Justin T. Clark, Ryan S. Teller
Publikováno v:
Journal of Controlled Release. 224:176-183
Intravaginal ring technology is generally limited to releasing low molecular weight species that can diffuse through the ring elastomer. To increase the diversity of drugs that can be delivered from intravaginal rings, we designed an IVR that contain
Publikováno v:
Antiviral Research. 100:255-258
Vaginal pre-exposure prophylaxis has focused heavily on gel formulations. Low adherence linked with frequent dosing and short therapeutic duration has emerged as the major reason for inconsistent efficacy outcomes with gels in clinical trials. Osmoti
Autor:
James M. Smith, R. Michael Hendry, Chuong Dinh, Ryan S. Teller, Umadevi Nagaraja, Janet M. McNicholl, Priya Srinivasan, Amy Martin, Patrick F. Kiser, Rachna Rastogi, Betsy C. Herold, Pedro M. M. Mesquita
Publikováno v:
Proceedings of the National Academy of Sciences. 110:16145-16150
Topical preexposure prophylaxis interrupts HIV transmission at the site of mucosal exposure. Intermittently dosed vaginal gels containing the HIV-1 reverse transcriptase inhibitor tenofovir protected pigtailed macaques depending on the timing of vira
Autor:
Pedro M. M. Mesquita, Patrick F. Kiser, Ryan S. Teller, Rachna Rastogi, Betsy C. Herold, N. Merna Torres, Theodore J. Segarra, Ashley Huber
Publikováno v:
Journal of Antimicrobial Chemotherapy. 67:1730-1738
OBJECTIVES: A safe and effective topical prevention strategy will likely require sustained delivery of potent antiviral drugs and a delivery system that simultaneously maximizes drug distribution and overcomes the behavioural challenges related to ad
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 82:160-167
Superparamagnetic iron oxide nanoparticles (SPIONs) have been receiving great attention lately in biomedical applications, such as in magnetic resonance imaging and drug delivery. However, their systemic administration still remains a challenge due t
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 79:164-173
The aim of this study was to investigate the haemocompatibility of poly(N-isopropylacrylamide)-co-poly(ethylene glycol), PNIPAAM-PEG based nanoparticles and the influence of poly(ethylene glycol), PEG on the interactions of nanoparticles with cells.
Publikováno v:
Drug Development and Industrial Pharmacy. 36:993-1004
The main objective of this study was to assess the flux enhancement of insulin transdermally by utilizing a complex of chemical enhancers in combination with modulated iontophoresis.The experiments were performed on porcine epidermis model under thre
Publikováno v:
Current Nanoscience. 5:409-416
The objective of the study was to evaluate the efficacy of insulin loaded polymerosomes in diabetic rat model. To achieve the purpose, amphiphilic triblock co-polymers of the class poly(caprolactone)-poly(ethylene glycol)-poly(caprolactone), CEC were
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 72:161-166
Self-assembled vesicles of poly(caprolactone)-poly(ethylene glycol)-poly(caprolactone) co-polymer of 122+/-20 nm were prepared by solvent evaporation method and analyzed morphologically by TEM and AFM. Transmission electron micrographs showed the pre