Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rachida Sihem Charrad"'
Autor:
Christine Chomienne, Claude Jasmin, Rachida-Sihem Charrad, Anne Glachant, Florence Smadja-Joffe, Michèle Allouche, Zeineb Gadhoum, Junyuan Qi
Publikováno v:
Blood. 99:290-299
Acute myeloid leukemia (AML) is a heterogeneous leukemia characterized by the blockage of myeloid differentiation at different stages, which define distinct AML subtypes. We have recently reported that the ligation of CD44 with 2 activating monoclona
Autor:
Stéphane Legras, Florence Smadja-Joffe, Jean-Pierre Levesque, Denis Clay, Kohji Morimoto, Claude Jasmin, Rachida Sihem Charrad, Caroline Le Bousse
Publikováno v:
Blood. 89:1905-1914
Adhesive interactions between CD34+ hematopoietic progenitor cells (HPC) and bone marrow stroma are crucial for normal hematopoiesis, yet their molecular bases are still poorly elucidated. We have investigated whether cell surface proteoglycan CD44 c
Autor:
Rachida Sihem Charrad, Catherine Greenland, Ali Bettaieb, Michèle Allouche, Florence Smadja-Joffe, Cécile Grignon
Publikováno v:
Europe PubMed Central
Adhesion molecules can improve hematopoietic cell survival; however, their role in leukemic cell resistance to drug-induced apoptosis is poorly documented. The CD44 adhesion molecule is strongly expressed on acute myeloid leukemia (AML) blasts. Using
Autor:
Bertrand Delpech, Claude Jasmin, Nicole Balitrand, Rachida-Sihem Charrad, Yue Li, Christine Chomienne, Florence Smadja-Joffe, Denis Clay
Publikováno v:
Nature medicine. 5(6)
Blockage in myeloid differentiation characterizes acute myeloid leukemia (AML); the stage of the blockage defines distinct AML subtypes (AML1/2 to AML5). Differentiation therapy in AML has recently raised interest because the survival of AML3 patient
Publikováno v:
Frontiers in Bioscience. 12:4362
Our studies show that activated autoreactive inflammatory T cells specific and autoantibodies to collagen (V) and cardiac myosin are consistently detected after lung and heart transplantation, respectively. Clonal expansion of these T cells occurs on
Autor:
Florence Smadja-Joffe, Claude Jasmin, Y. Li, Rachida-Sihem Charrad, Z. Ghadoum, Christine Chomienne
Publikováno v:
Experimental Hematology. 28:1493
CD44-ligation with the anti-CD44 antibodies A3D8 and H90 triggers terminal differentiation in AML1/2 to AML5 blasts (Charrad et al, Nat Med, 5:669, 1999). Here we show that A3D8 and H90 inhibits the proliferation of myeloid leukemia cell lines HL60,