Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Rachida Guennoun"'
Autor:
Ivan J. Esperante, Maria Meyer, Carolina Banzan, Maria Sol Kruse, Analia Lima, Paulina Roig, Rachida Guennoun, Michael Schumacher, Alejandro F. De Nicola, Maria Claudia Gonzalez Deniselle
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 428 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal motoneuron degenerative disease that is associated with demyelination. The Wobbler (WR) mouse exhibits motoneuron degeneration, gliosis and myelin deterioration in the cervical spinal cord. Since male WR
Externí odkaz:
https://doaj.org/article/e42a650e5bc445718581441886d8724c
Autor:
Morgane Davezac, Rana Zahreddine, Melissa Buscato, Natalia F. Smirnova, Chanaelle Febrissy, Henrik Laurell, Silveric Gilardi-Bresson, Marine Adlanmerini, Philippe Liere, Gilles Flouriot, Rachida Guennoun, Muriel Laffargue, Jean-Michel Foidart, Françoise Lenfant, Jean-François Arnal, Raphaël Métivier, Coralie Fontaine
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
The main estrogen, 17β-estradiol (E2), exerts several beneficial vascular actions through estrogen receptor α (ERα) in endothelial cells. However, the impact of other natural estrogens such as estriol (E3) and estetrol (E4) on arteries remains poo
Externí odkaz:
https://doaj.org/article/cee391bdb2374d7ba32e1f7c699de3f8
Autor:
Pauline Gaignard, Philippe Liere, Patrice Thérond, Michael Schumacher, Abdelhamid Slama, Rachida Guennoun
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
The mitochondria have a fundamental role in both cellular energy supply and oxidative stress regulation and are target of the effects of sex steroids, particularly the neuroprotective ones. Aging is associated with a decline in the levels of differen
Externí odkaz:
https://doaj.org/article/20b32fcc9e5b4ef59445b1d206eca7a0
Autor:
Marı́a Claudia Gonzalez Deniselle, Juan José López-Costa, Jorge Pecci Saavedra, Luciana Pietranera, Susana L. Gonzalez, Laura Garay, Rachida Guennoun, Michael Schumacher, Alejandro F. De Nicola
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 3, Pp 457-468 (2002)
Motor neuron degeneration characterizes the spinal cord of patients with amyotrophic lateral sclerosis and the Wobbler mouse mutant. Considering that progesterone (PROG) provides neuroprotection in experimental ischemia and injury, its potential role
Externí odkaz:
https://doaj.org/article/0a0ab21be2c9415cb7cd91cd73c1eb54
Autor:
Laura Garay, Maria Meyer, Alejandro F. De Nicola, Rachida Guennoun, Maria Claudia Gonzalez Deniselle, Maria Sol Kruse, Michael Schumacher
Publikováno v:
Cellular and Molecular Neurobiology. 42:23-40
Progesterone regulates a number of processes in neurons and glial cells not directly involved in reproduction or sex behavior. Several neuroprotective effects are better observed under pathological conditions, as shown in the Wobbler mouse model of a
Autor:
Neïké Fernandez, Anthony Petit, Antoine Pianos, Léna Haddad, Michael Schumacher, Philippe Liere, Rachida Guennoun
Publikováno v:
Endocrinology. 164(1)
Ischemic stroke is a leading cause of disability and death, and aging is the main nonmodifiable risk factor. Following ischemia, neuroactive steroids have been shown to play a key role in cerebroprotection. Thus, brain steroid concentrations at the t
Autor:
Michael Schumacher, Agustina Lara, Maria Claudia Gonzalez Deniselle, Noelia Paula Di Giorgio, Rachida Guennoun, Alejandro F. De Nicola, Iván Esperante, Gisella Gargiulo-Monachelli, Philippe Liere, Maria Meyer
Publikováno v:
Molecular Neurobiology. 58:2088-2106
Patients suffering of amyotrophic lateral sclerosis (ALS) present motoneuron degeneration leading to muscle atrophy, dysphagia, and dysarthria. The Wobbler mouse, an animal model of ALS, shows a selective loss of motoneurons, astrocytosis, and microg
Autor:
Alejandro F, De Nicola, María, Meyer, Laura, Garay, Maria Sol, Kruse, Michael, Schumacher, Rachida, Guennoun, Maria Claudia, Gonzalez Deniselle
Publikováno v:
Cellular and molecular neurobiology. 42(1)
Progesterone regulates a number of processes in neurons and glial cells not directly involved in reproduction or sex behavior. Several neuroprotective effects are better observed under pathological conditions, as shown in the Wobbler mouse model of a
Autor:
Rachida Guennoun, Laura Garay, Maria Luz Leicaj, Michael Schumacher, Paulina Roig, Dalila Nj Mancino, Alejandro F. De Nicola, Analia Lima
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 207
Progesterone is involved in dendritogenesis, synaptogenesis and maturation of cerebellar Purkinge cells, major sites of steroid synthesis in the brain. To study a possible time-relationship between myelination, neurosteroidogenesis and steroid recept
Autor:
Agustina, Lara, Iván, Esperante, Maria, Meyer, Philippe, Liere, Noelia, Di Giorgio, Michael, Schumacher, Rachida, Guennoun, Gisella, Gargiulo-Monachelli, Alejandro Federico, De Nicola, Maria Claudia, Gonzalez Deniselle
Publikováno v:
Molecular neurobiology. 58(5)
Patients suffering of amyotrophic lateral sclerosis (ALS) present motoneuron degeneration leading to muscle atrophy, dysphagia, and dysarthria. The Wobbler mouse, an animal model of ALS, shows a selective loss of motoneurons, astrocytosis, and microg