Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rachid Zagani"'
Autor:
Klare L. Bersch, Kristen E. DeMeester, Rachid Zagani, Shuyuan Chen, Kimberly A. Wodzanowski, Shuzhen Liu, Siavash Mashayekh, Hans-Christian Reinecker, Catherine L. Grimes
Publikováno v:
ACS Central Science, Vol 7, Iss 4, Pp 688-696 (2021)
Externí odkaz:
https://doaj.org/article/1c648835b7ca46ac9d60b777f89121f5
Autor:
Yun Zhao, Rachid Zagani, Sung-Moo Park, Naohiro Yoshida, Pankaj Shah, Hans-Christian Reinecker
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The transcription factor IRF5 is essential for immune defense against pathogens. Here, the authors show that the microtubule-associated factor GEF-H1 plays a critical role in host defense against Listeria monocytogenes in macrophages via activation o
Externí odkaz:
https://doaj.org/article/116dd64c0f8148448455c70c181f4b02
Autor:
Abhishek S. Kashyap, Laura Fernandez-Rodriguez, Yun Zhao, Gianni Monaco, Marcel P. Trefny, Naohiro Yoshida, Kea Martin, Ashwani Sharma, Natacha Olieric, Pankaj Shah, Michal Stanczak, Nicole Kirchhammer, Sung-Moo Park, Sebastien Wieckowski, Heinz Laubli, Rachid Zagani, Benjamin Kasenda, Michel O. Steinmetz, Hans-Christian Reinecker, Alfred Zippelius
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3367-3380.e8 (2019)
Summary: Dendritic cell (DC) activation is a critical step for anti-tumor T cell responses. Certain chemotherapeutics can influence DC function. Here we demonstrate that chemotherapy capable of microtubule destabilization has direct effects on DC fun
Externí odkaz:
https://doaj.org/article/21a0d97cff3b46a0a90aae9154512253
Autor:
Rachid Zagani, Siavash Mashayekh, Shuzhen Liu, Hans Christian Reinecker, Catherine L. Grimes, Klare L. Bersch, Kimberly A. Wodzanowski, Kristen E. DeMeester, Shuyuan Chen
Publikováno v:
ACS Central Science, Vol 7, Iss 4, Pp 688-696 (2021)
ACS Central Science
ACS Central Science
The human innate immune system responds to both pathogen and commensal bacteria at the molecular level using bacterial peptidoglycan (PG) recognition elements. Traditionally, synthetic and commercially accessible PG monosaccharide units known as mura
Autor:
Rachid Zagani, Yun Zhao, Sung-Moo Park, Hans Christian Reinecker, Naohiro Yoshida, Tatsushi Omatsu, Pankaj Shah
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-15 (2019)
The innate immune response following infection with entero-invasive bacterial species is triggered upon release of cyclic di-guanylate monophosphate (c-di-GMP) into the host cell cytosol. Bacterial c-di-GMP activates the intracellular Sensor Stimulat
Autor:
Rachid Zagani, Kristen E. DeMeester, Kimberly A. Wodzanowski, Klare L. Bersch, Catherine L. Grimes, Hans Christian Reinecker
The human innate immune system responds to both pathogen and commensal bacteria at the molecular level using bacterial peptidoglycan (PG) recognition elements. Traditionally, synthetic and commercially accessible PG monosaccharide units known as mura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab8cafba533fe8d19f5cc4c15e6f05e
https://doi.org/10.1101/2020.09.03.278705
https://doi.org/10.1101/2020.09.03.278705
Autor:
Sung-Moo, Park, Tatsushi, Omatsu, Yun, Zhao, Naohiro, Yoshida, Pankaj, Shah, Rachid, Zagani, Hans-Christian, Reinecker
Publikováno v:
Communications Biology
The innate immune response following infection with entero-invasive bacterial species is triggered upon release of cyclic di-guanylate monophosphate (c-di-GMP) into the host cell cytosol. Bacterial c-di-GMP activates the intracellular Sensor Stimulat
Autor:
Michal A. Stanczak, Pankaj Shah, Naohiro Yoshida, Benjamin Kasenda, Nicole Kirchhammer, Abhishek S. Kashyap, Sung-Moo Park, Rachid Zagani, Sébastien Wieckowski, Laura Fernandez-Rodriguez, Gianni Monaco, Alfred Zippelius, Yun Zhao, Marcel P. Trefny, Hans Christian Reinecker, Ashwani Sharma, Michel O. Steinmetz, Kea Martin, Heinz Läubli, Natacha Olieric
Publikováno v:
Cell reports
Cell Reports, Vol 28, Iss 13, Pp 3367-3380.e8 (2019)
Cell Reports, Vol 28, Iss 13, Pp 3367-3380.e8 (2019)
SUMMARY Dendritic cell (DC) activation is a critical step for anti-tumor T cell responses. Certain chemotherapeutics can influence DC function. Here we demonstrate that chemotherapy capable of microtubule destabilization has direct effects on DC func
Autor:
Naohiro Yoshida, Rachid Zagani, Sung-Moo Park, Pankaj Shah, Yun Zhao, Hans Christian Reinecker
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
During infection, transcription factor interferon regulatory factor 5 (IRF5) is essential for the control of host defense. Here we show that the microtubule-associated guanine nucleotide exchange factor (GEF)-H1, is required for the phosphorylation o
Publikováno v:
Oncotarget
The G0/G1 switch gene 2 (G0S2) is methylated and silenced in a wide range of human cancers. The protein encoded by G0S2 is an endogenous inhibitor of lipid catabolism that directly binds adipose triglyceride lipase (ATGL). ATGL is the rate-limiting s