Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rachid SK"'
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e25987- (2024)
At a time when the semiconductor industry is facing major difficulties in maintaining sluggish growth, new high-level synthesis tools are repositioning FPGAs as a leading technology for hardware-based algorithm acceleration, in the face of CPUs based
Externí odkaz:
https://doaj.org/article/458390ee27494b7188f3bc40ae915036
Autor:
Sophia Bigot, Philippe Leprohon, Abimael Vasquez, Rohit Bhadoria, Rachid Skouta, Marc Ouellette
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 21, Iss , Pp 13-20 (2023)
Treatments against leishmaniasis are limited and the development of new molecules is crucial. One class of developmental drug that has shown activity against the parasite Leishmania are thiophene derivatives. Here we synthetized thirty-eight novel th
Externí odkaz:
https://doaj.org/article/35d0155b6a324618b15718e6f4f9f53a
Autor:
Adebimpe Adesina, Rachid Skouta
Publikováno v:
Molecules, Vol 29, Iss 1, p 249 (2024)
The N-phenylquinoneimine scaffold is a versatile synthetic platform that has gained significant attention in the field of drug discovery due to its structural diversity and capacity to interact with biologically relevant targets. This review explores
Externí odkaz:
https://doaj.org/article/9ac7a936f1014f7b91e8c18e3373cdb4
Autor:
Oscar Claudio-Ares, Jeileen Luciano-Rodríguez, Yolmarie L. Del Valle-González, Selene L. Schiavone-Chamorro, Alex J. Pastor, Javier O. Rivera-Reyes, Carmen L. Metzler, Lizandra M. Domínguez-Orona, Brenda Lee Vargas-Pérez, Rachid Skouta, Arthur D. Tinoco
Publikováno v:
Inorganics, Vol 12, Iss 1, p 26 (2024)
The discovery of regulated cell death (RCD) revolutionized chemotherapy. With caspase-dependent apoptosis initially being thought to be the only form of RCD, many drug development strategies aimed to synthesize compounds that turn on this kind of cel
Externí odkaz:
https://doaj.org/article/3b880c2711de4e2db4716f90a1644433
Autor:
Kamari Weaver, Rachid Skouta
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 891 (2022)
The selenoprotein glutathione peroxidase 4 (GPX4) is one of the main antioxidant mediators in the human body. Its central function involves the reduction of complex hydroperoxides into their respective alcohols often using reduced Glutathione (GSH) a
Externí odkaz:
https://doaj.org/article/6ac002cddd924564bfa8f9d3bf292a04
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 66 (2022)
Despite the scientific advancements, organophosphate (OP) poisoning continues to be a major threat to humans, accounting for nearly one million poisoning cases every year leading to at least 20,000 deaths worldwide. Oximes represent the most importan
Externí odkaz:
https://doaj.org/article/d336654885f04546ac7dd7a390fe328c
Autor:
Anahis Tena, Eduardo Peru, Luis E. Martinetti, Jose C. Cano, Carla D. Loyola Baltazar, Amy E. Wagler, Rachid Skouta, Karine Fenelon
Publikováno v:
Brain and Behavior, Vol 9, Iss 8, Pp n/a-n/a (2019)
Abstract Introduction Lead (Pb) exposure yielding blood lead levels (BLL) as low as 2 µg/dl in children is an international problem. More common in US low‐income neighborhoods, childhood Pb exposure can cause behavioral and cognitive deficits, inc
Externí odkaz:
https://doaj.org/article/4d9432e25a3c43bb8ab1fc7a9641b682
Autor:
Rachid Skouta
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 466 (2021)
Maintaining the physiological level of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the body is highly important in the fight against radical species in the context of human health [...]
Externí odkaz:
https://doaj.org/article/8c9c006460f74ad0a34a9df69d4e31e5
Autor:
Jyothi Dhuguru, Rachid Skouta
Publikováno v:
Molecules, Vol 25, Iss 7, p 1615 (2020)
Lung cancer is the leading cause of death in men and women worldwide, affecting millions of people. Between the two types of lung cancers, non-small cell lung cancer (NSCLC) is more common than small cell lung cancer (SCLC). Besides surgery and radio
Externí odkaz:
https://doaj.org/article/0db0350b18ec424d9827bb5aba191108
Autor:
Karla Morán-Santibañez, Abimael H. Vasquez, Armando Varela-Ramirez, Veronica Henderson, Janae Sweeney, Valerie Odero-Marah, Karine Fenelon, Rachid Skouta
Publikováno v:
Antioxidants, Vol 8, Iss 10, p 427 (2019)
Creosote bush (Larrea tridentata; LT) leaves extracts were tested for their potential efficacy to mitigate cellular oxidative stress on human SH-SY5Y cells. Here, the differential nuclear staining assay, a bioimager system, and flow cytometric protoc
Externí odkaz:
https://doaj.org/article/7957a9106f0b42f9b8077a2a0c201ab9