Výsledky vyhledávání - "Rachid Bouzammit"

Akademický článek

In silico insights into the design of novel NR2B-selective NMDA receptor antagonists: QSAR modeling, ADME-toxicity predictions, molecular docking, and molecular dynamics investigations

Autor: Mohamed El fadili, Mohammed Er-rajy, Somdutt Mujwar, Abduljelil Ajala, Rachid Bouzammit, Mohammed Kara, Hatem A. Abuelizz, Sara Er-rahmani, Menana Elhallaoui

Publikováno v: BMC Chemistry, Vol 18, Iss 1, Pp 1-22 (2024)

Abstract Based on a structural family of thirty-two NR2B-selective N-Methyl-D-Aspartate receptor (NMDAR) antagonists, two phenylpiperazine derivatives labeled C37 and C39 were conceived thanks to molecular modeling techniques, as novel NMDAR inhibito

Externí odkaz: https://doaj.org/article/68b2ece01da4488b885bf6c3bc083b71

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Akademický článek

New Triazole-Isoxazole Hybrids as Antibacterial Agents: Design, Synthesis, Characterization, In Vitro, and In Silico Studies

Autor: Rachid Bouzammit, Salim Belchkar, Mohamed El fadili, Youssra Kanzouai, Somdutt Mujwar, Mohammed M. Alanazi, Mohammed Chalkha, Asmae Nakkabi, Mohamed Bakhouch, Emese Gal, Luiza Ioana Gaina, Ghali al houari

Publikováno v: Molecules, Vol 29, Iss 11, p 2510 (2024)

Novel isoxazole–triazole conjugates have been efficiently synthesized using 3-formylchromone as starting material according to a multi-step synthetic approach. The structures of the target conjugates and intermediate products were characterized by

Externí odkaz: https://doaj.org/article/b96662f3f42f4b3aa825af06c89a9e83

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Synthesis of new spiroheterocycles-fused isoxazoline from 2-arylidenes-3-phenyl-1-indanones through a regio-and diastereospecific 1,3-dipolar cycloaddition

Autor: Asmae Nakkabi, Youssra Kanzouai, Mohamed Akhazzane, Rachid Bouzammit, Asmae Mahfoud, Abdelali Kerbal, Mohamed El Yazidi, Ghali Al Houari, Mohamed Bakhouch

Publikováno v: Mediterranean Journal of Chemistry. 11:194

New spiroisoxazolines 3 have been synthesized by 1,3-dipolar cycloaddition of arylnitrile oxides with 2-arylidenes-3-phenyl-1-indanones. The reaction occurs in a regiospecific and diastereospecific manner and leads to one cycloadduct in all the cases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dfaf096244d2886a096f1d2ec5c2441f
https://doi.org/10.13171/mjc02105141076gh

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Akademický článek

In silico insights into the design of novel NR2B-selective NMDA receptor antagonists: QSAR modeling, ADME-toxicity predictions, molecular docking, and molecular dynamics investigations.

Autor: El fadili, Mohamed¹ (AUTHOR) mohamed.elfadili@usmba.ac.ma, Er-rajy, Mohammed¹ (AUTHOR), Mujwar, Somdutt² (AUTHOR), Ajala, Abduljelil³ (AUTHOR), Bouzammit, Rachid⁴ (AUTHOR), Kara, Mohammed⁵ (AUTHOR), Abuelizz, Hatem A.⁶ (AUTHOR), Er-rahmani, Sara⁷ (AUTHOR), Elhallaoui, Menana¹ (AUTHOR)

Publikováno v: BMC Chemistry. 7/31/2024, Vol. 18 Issue 1, p1-22. 22p.

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Akademický článek

New Triazole-Isoxazole Hybrids as Antibacterial Agents: Design, Synthesis, Characterization, In Vitro, and In Silico Studies.

Autor: Bouzammit, Rachid¹ (AUTHOR) rachid.bouzammit@usmba.ac.ma, Belchkar, Salim² (AUTHOR) salim.belchkar@usmba.ac.ma, El fadili, Mohamed³ (AUTHOR) mohamed.elfadili@usmba.ac.ma, Kanzouai, Youssra¹ (AUTHOR) mohammed.chalkha1@usmba.ac.ma, Mujwar, Somdutt⁴ (AUTHOR) somdutt.mujwar@chitkara.edu.in, Alanazi, Mohammed M.⁵ (AUTHOR) mmalanazi@ksu.edu.sa, Chalkha, Mohammed^1,6 (AUTHOR) asmaenakkabi@yahoo.fr, Nakkabi, Asmae^1,6 (AUTHOR) ghalialhouari@gmail.com, Bakhouch, Mohamed⁷ (AUTHOR) bakhouch.m@ucd.ac.ma, Gal, Emese⁸ (AUTHOR) emese.gal@ubbcluj.ro, Gaina, Luiza Ioana⁸ (AUTHOR) gaina.ioana.luiza@gmail.com, al houari, Ghali¹ (AUTHOR)

Publikováno v: Molecules. Jun2024, Vol. 29 Issue 11, p2510. 22p.

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Periodical

Investigators at University of Sidi Mohamed Ben Abdellah Discuss Findings in Antibiotics (Synthesis, Characterization, Dft Mechanistic Study, Antibacterial Activity, Molecular Modeling, and Admet Properties of Novel Chromone-isoxazole Hybrids).

Publikováno v: Drug Week; 10/22/2024, p953-953, 1p

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Periodical

Research from University Sidi Mohamed Ben Abdellah Yields New Study Findings on Pseudomonas aeruginosa (New Triazole-Isoxazole Hybrids as Antibacterial Agents: Design, Synthesis, Characterization, In Vitro, and In Silico Studies).

Publikováno v: Drug Week; 7/5/2024, p2445-2445, 1p

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Periodical

Studies from University of Sidi Mohamed Ben Abdellah Reveal New Findings on Antibacterial Agents (Design, Synthesis, In-vitro and In-silico Studies of Chromone-isoxazoline Conjugates As Anti-bacterial Agents).

Publikováno v: Drug Week; 12/12/2023, p2785-2785, 1p

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