Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rachelle M. Buchanan"'
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51437 (2012)
BACKGROUND: In adult rats, initial exposure to antigens by a mucosal route triggers tolerance such that any subsequent re-exposure, even by a systemic route, results in suppression of immunity. The newborn's gut is semi-permeable for a finite period
Externí odkaz:
https://doaj.org/article/dbbfaca2e28342e992085cc8c47fd434
Publikováno v:
Procedia in Vaccinology
Neonatal Diarrheal Disease is responsible for significant economic losses to the livestock industries in Canada and around the world. Microbes responsible are diverse and include Escherichia coli, Salmonella, Rotavirus, Coronavirus and Cryptosporidia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6e58f58feb6a55c814a68e9521120a
Autor:
Lorne A. Babiuk, Volker Gerdts, Andrew A. Potter, Aleksandra Gracia, Scott A. Halperin, Monika Polewicz, Stacy Strom, Rachelle M. Buchanan
Publikováno v:
Vaccine. 29:7718-7726
Whooping cough caused by infection with Bordetella pertussis, is a serious illness in infants and young children. Mortality due to whooping cough is being reported in infants too young to be immunized as well as those who have not completed their ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9932cf5a65cab55d40e207b525161c4f
https://doi.org/10.1016/j.vaccine.2011.07.135
https://doi.org/10.1016/j.vaccine.2011.07.135
Autor:
Lorne A. Babiuk, Srinivas Garlapati, Nelson F. Eng, Heather L. Wilson, Volker Gerdts, George Mutwiri, Rachelle M. Buchanan
Publikováno v:
Vaccine. 28:8306-8314
We generated poly[di(carboxylatophenoxy)-phosphazene] (PCPP) microparticles encapsulating ovalbumin (OVA) and CpG of 0.5-2.5 μm in diameter with an encapsulation efficiency of approximately 63% and 95% respectively. In mice the microparticles genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78eb264d3db00297be4a832ec1ec410d
https://doi.org/10.1016/j.vaccine.2010.09.080
https://doi.org/10.1016/j.vaccine.2010.09.080
Autor:
Marina R. Facci, Volker Gerdts, Gaël Auray, Lorne A. Babiuk, Jill van Kessel, Rachelle M. Buchanan
Publikováno v:
Molecular Immunology. 47:2103-2111
Dendritic cells (DCs) are at the interface of innate and adaptive immune responses. Once activated via triggering of their pattern recognition receptors (PRRs), they acquire a mature state and migrate to the lymph nodes where they activate T cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674aefb799aabfdae1f4ff7bed7af676
https://doi.org/10.1016/j.molimm.2010.03.016
https://doi.org/10.1016/j.molimm.2010.03.016
Autor:
Heather L. Wilson, Volker Gerdts, Siew Hon Ng, Rachelle M. Buchanan, J. Alex Pasternak, George Mutwiri, Sonja Mertins
Publikováno v:
BMC Veterinary Research
Background We previously determined that newborn piglets orally gavaged with Ovalbumin (OVA) responded to systemic OVA re-exposure with tolerance; if adjuvants were included in oral vaccine, piglets responded with antibody-mediated immunity (Vet Immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4425cd27dfe1553cf2bec9a810dd619
http://europepmc.org/articles/PMC4357157
http://europepmc.org/articles/PMC4357157
Autor:
Volker Gerdts, Sam Attah-Poku, Rachelle M. Buchanan, Hugh G.G. Townsend, Shokrollah Elahi, Lorne A. Babiuk
Publikováno v:
Infection and Immunity. 74:2338-2352
Innate immunity plays an important role in protection against respiratory infections in humans and animals. Host defense peptides such as beta-defensins represent major components of innate immunity. We recently developed a novel porcine model of per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aabf067f658f9868932bac0fb0dd1ae
https://doi.org/10.1128/iai.74.4.2338-2352.2006
https://doi.org/10.1128/iai.74.4.2338-2352.2006
Autor:
Lorne A. Babiuk, Rachelle M. Buchanan, Marina R. Facci, Jill van Kessel, Gael Auray, Volker Gerdts
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e59629 (2013)
PLoS ONE
PLoS ONE
The neonatal immune system is often considered as immature or impaired compared to the adult immune system. This higher susceptibility to infections is partly due to the skewing of the neonatal immune response towards a Th2 response. Activation and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da493fdebf47e616cee3b87996face7
http://europepmc.org/articles/PMC3648567?pdf=render
http://europepmc.org/articles/PMC3648567?pdf=render
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51437 (2012)
PLoS ONE
PLoS ONE
BACKGROUND: In adult rats, initial exposure to antigens by a mucosal route triggers tolerance such that any subsequent re-exposure, even by a systemic route, results in suppression of immunity. The newborn's gut is semi-permeable for a finite period
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce9bcd7954f2a16b9ef8866e8f67f9e
http://europepmc.org/articles/PMC3520849?pdf=render
http://europepmc.org/articles/PMC3520849?pdf=render
Autor:
Natasa Arsic, George Mutwiri, Rachelle M. Buchanan, Philip J. Griebel, Heather L. Wilson, Andrew A. Potter, Lorne A. Babiuk, Yurij Popowych, Crystal Dagenais
Publikováno v:
Veterinary immunology and immunopathology. 145(1-2)
We previously reported that CD21+ B cells purified from bovine blood do not respond to CpG-ODN stimulation unless either CD14+ monocytes or B-cell Activating Factor (BAFF), a cytokine produced by activated monocytes, are present. In this report, we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7afc6231fdbeb8e1fed253c521fc0d3
https://pubmed.ncbi.nlm.nih.gov/22264737
https://pubmed.ncbi.nlm.nih.gov/22264737