Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rachelle Balez"'
Autor:
Tamasha Malepathirana, Damith Senanayake, Vini Gautam, Martin Engel, Rachelle Balez, Michael D. Lovelace, Gayathri Sundaram, Benjamin Heng, Sharron Chow, Christopher Marquis, Gilles J. Guillemin, Bruce Brew, Chennupati Jagadish, Lezanne Ooi, Saman Halgamuge
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Longitudinal studies that continuously generate data enable the capture of temporal variations in experimentally observed parameters, facilitating the interpretation of results in a time-aware manner. We propose IL-VIS (incrementally learned
Externí odkaz:
https://doaj.org/article/aa2a103c819e4d3bb068dba74abcfa87
Autor:
Simon Maksour, Rocio K. Finol-Urdaneta, Amy J. Hulme, Mauricio e Castro Cabral-da-Silva, Helena Targa Dias Anastacio, Rachelle Balez, Tracey Berg, Calista Turner, Sonia Sanz Muñoz, Martin Engel, Predrag Kalajdzic, Leszek Lisowski, Kuldip Sidhu, Perminder S. Sachdev, Mirella Dottori, Lezanne Ooi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Alzheimer’s disease (AD) is a devastating neurodegenerative condition that affects memory and cognition, characterized by neuronal loss and currently lacking a cure. Mutations in PSEN1 (Presenilin 1) are among the most common causes of early-onset
Externí odkaz:
https://doaj.org/article/05ddb18cdd304f6b868ce5b095ddf6d6
Autor:
Simon Maksour, Neville Ng, Amy J. Hulme, Sara Miellet, Martin Engel, Sonia Sanz Muñoz, Rachelle Balez, Ben Rollo, Rocio K. Finol-Urdaneta, Lezanne Ooi, Mirella Dottori
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32680- (2024)
Repressor element-1 silencing transcription factor (REST) is a transcriptional repressor involved in neurodevelopment and neuroprotection. REST forms a complex with the REST corepressors, CoREST1, CoREST2, or CoREST3 (encoded by RCOR1, RCOR2, and RCO
Externí odkaz:
https://doaj.org/article/2ccd3caa1e844c4b86d0e4c2a10532f7
Autor:
Martin Engel, Rachelle Balez, Sonia Sanz Muñoz, Mauricio Castro Cabral-da-Silva, Claire Helen Stevens, Monique Bax, Dzung Do-Ha, Kuldip Sidhu, Perminder Sachdev, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 32, Iss , Pp 135-138 (2018)
Peripheral dermal fibroblasts (DF) from a healthy 56 year old female were obtained from the Centre for Healthy Brain Ageing (CHeBA) Biobank, University of New South Wales, under the material transfer agreement with the University of Wollongong. DFs w
Externí odkaz:
https://doaj.org/article/7494d0179d9e4674a43300d2c668ce7c
Autor:
Sonia Sanz Muñoz, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Tracey Berg, Martin Engel, Monique Bax, Dzung Do-Ha, Claire H. Stevens, Mark Greenough, Ashley Bush, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 31, Iss , Pp 227-230 (2018)
The induced pluripotent stem cell (iPSC) lines UOWi002-A and UOWi003-A were reprogrammed from dermal fibroblasts via mRNA transfection. Dermal fibroblasts from a 56 year old female caucasian familial Alzheimer's disease patient carrying A246E mutatio
Externí odkaz:
https://doaj.org/article/0cbc1736d14d4a8db79ce19b3dfc783a
Autor:
Rachelle Balez, Tracey Berg, Monique Bax, Sonia Sanz Muñoz, Mauricio C. Cabral-da-Silva, Martin Engel, Dzung Do-Ha, Claire H. Stevens, Dominic Rowe, Shu Yang, Ian P. Blair, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 42, Iss , Pp - (2020)
Dermal fibroblasts were donated by a 43 year old male patient with clinically diagnosed familial amyotrophic lateral sclerosis (ALS), carrying the SOD1E101G mutation. The induced pluripotent stem cell (iPSC) line UOWi007-A was generated using repeate
Externí odkaz:
https://doaj.org/article/dae665f88de044ac8ff397bfa9c6cdd6
Autor:
Monique Bax, Rachelle Balez, Sonia Sanz Muñoz, Dzung Do-Ha, Claire H. Stevens, Tracey Berg, Mauricio C. Cabral-da-Silva, Martin Engel, Garth Nicholson, Shu Yang, Ian P. Blair, Lezanne Ooi
Publikováno v:
Stem Cell Research, Vol 40, Iss , Pp - (2019)
Dermal fibroblasts from a 59 year old male patient with amyotrophic lateral sclerosis (symptomatic at the time of collection), attributed to a mutation in the cyclin F gene (CCNFS621G), were reprogrammed using mRNA and microRNA-delivered OSKM factors
Externí odkaz:
https://doaj.org/article/24aceff198744133ade4e5f0a2bd9611
Autor:
Sonia Sanz Muñoz, Martin Engel, Rachelle Balez, Dzung Do-Ha, Mauricio Castro Cabral-da-Silva, Damian Hernández, Tracey Berg, Jennifer A. Fifita, Natalie Grima, Shu Yang, Ian P. Blair, Garth Nicholson, Anthony L. Cook, Alex W. Hewitt, Alice Pébay, Lezanne Ooi
Publikováno v:
Cells, Vol 9, Iss 9, p 2018 (2020)
The study of neurodegenerative diseases using pluripotent stem cells requires new methods to assess neurodevelopment and neurodegeneration of specific neuronal subtypes. The cholinergic system, characterized by its use of the neurotransmitter acetylc
Externí odkaz:
https://doaj.org/article/89e7ab23e46047a6a0f8fe91d1fcfe64
Autor:
Monique Bax, Jessie McKenna, Dzung Do-Ha, Claire H. Stevens, Sarah Higginbottom, Rachelle Balez, Mauricio e Castro Cabral-da-Silva, Natalie E. Farrawell, Martin Engel, Philip Poronnik, Justin J. Yerbury, Darren N. Saunders, Lezanne Ooi
Publikováno v:
Cells, Vol 8, Iss 6, p 581 (2019)
The ubiquitin proteasome system (UPS) plays an important role in regulating numerous cellular processes, and a dysfunctional UPS is thought to contribute to motor neuron disease. Consequently, we sought to map the changing ubiquitome in human iPSCs d
Externí odkaz:
https://doaj.org/article/fb3bfa9cf941450b97ac10ec0bf3e5ef
Autor:
Jennilee M. Davidson, Sharlynn S. L. Wu, Stephanie L. Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M. Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L. Williams, Marco Morsch, Ian P. Blair, Antonio Di Ieva, Shu Yang, Roger S. Chung, Albert Lee
Publikováno v:
Molecular Neurobiology.
Amyotrophic lateral sclerosis (ALS)- and frontotemporal dementia (FTD)-linked mutations in CCNF have been shown to cause dysregulation to protein homeostasis. CCNF encodes for cyclin F, which is part of the cyclin F-E3 ligase complex SCFcyclinF known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e297e94dcdb8abb7f6625ed5a35097
https://doi.org/10.1007/s12035-023-03355-2
https://doi.org/10.1007/s12035-023-03355-2