Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Rachele Rosati"'
Autor:
Marwah Al-Aloosi, Amanda M. Prechtl, Payel Chatterjee, Brady Bernard, Christopher J. Kemp, Rachele Rosati, Robert L. Diaz, Lauren R. Appleyard, Shalini Pereira, Alex Rajewski, Amber McDonald, Eva J. Gordon, Carla Grandori
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Patients presenting with stage 4 ovarian carcinoma, including low-grade serous disease, have a poor prognosis. Although platinum-based therapies can offer some response, these therapies are associated with many side effects, and treatment resistance
Externí odkaz:
https://doaj.org/article/fcc76ebb292445b4b3f929be800bb6b7
Autor:
Heidi J. Gray, Payel Chatterjee, Rachele Rosati, Lauren R. Appleyard, Grace J. Durenberger, Robert L. Diaz, Hallie A. Swan, Danielle Peretti, Maddy Pollastro, Trevor Ainge, Katannya Kapeli, Shalini Pereira, Astrid L. Margossian, Kalyan Banda, Barbara A. Goff, Elizabeth M. Swisher, Brady Bernard, Christopher J. Kemp, Carla Grandori
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Low-grade serous ovarian cancer (LGSOC) typically responds poorly to standard platinum-based chemotherapy and new therapeutic approaches are needed. We describe a remarkable response to targeted therapy in a patient with platinum-resistant,
Externí odkaz:
https://doaj.org/article/8a9cc59b3ce64630836df3b6b10cdaf8
Autor:
Goldie Y.L. Lui, Reid Shaw, Franz X. Schaub, Isabella N. Stork, Kay E. Gurley, Caroline Bridgwater, Robert L. Diaz, Rachele Rosati, Hallie A. Swan, Tan A. Ince, Thomas C. Harding, Vijayakrishna K. Gadi, Barbara A. Goff, Christopher J. Kemp, Elizabeth M. Swisher, Carla Grandori
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102988- (2020)
Background: Homologous recombination deficiencies (HRD) are present in approximately half of epithelial ovarian cancers, for which PARP inhibitors (PARPi) are becoming a preferred treatment option. However, a considerable proportion of these carcinom
Externí odkaz:
https://doaj.org/article/3e5e8f98aab5402f8b8ee8783a2b4b38
Autor:
Loredana Puca, Rohan Bareja, Davide Prandi, Reid Shaw, Matteo Benelli, Wouter R. Karthaus, Judy Hess, Michael Sigouros, Adam Donoghue, Myriam Kossai, Dong Gao, Joanna Cyrta, Verena Sailer, Aram Vosoughi, Chantal Pauli, Yelena Churakova, Cynthia Cheung, Lesa Dayal Deonarine, Terra J. McNary, Rachele Rosati, Scott T. Tagawa, David M. Nanus, Juan Miguel Mosquera, Charles L. Sawyers, Yu Chen, Giorgio Inghirami, Rema A. Rao, Carla Grandori, Olivier Elemento, Andrea Sboner, Francesca Demichelis, Mark A. Rubin, Himisha Beltran
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
There are few available models to study neuroendocrine prostate cancer. Here they develop and characterize patient derived organoids from metastatic lesions, use these models to show the role of EZH2 in driving neuroendocrine phenotype, and perform h
Externí odkaz:
https://doaj.org/article/6298c3191ca44642a1ee5adc286008a4
Autor:
Mark A. Rubin, Lewis C. Cantley, Carla Grandori, Christopher J. Kemp, Francesca Demichelis, Himisha Beltran, Olivier Elemento, Brady Bernard, Vijayakrishna K. Gadi, Brooke E. Emerling, Bishoy M. Faltas, Brian Robinson, Juan Miguel Mosquera, Rema Rao, David Pisapia, Joanna Triscott, Cynthia Cheung, Yelena Churakova, Terra J. McNary, Rachele Rosati, Loredana Puca, Michael Augello, Verena Sailer, Andrea Sboner, Tarcisio Fedrizzi, Reid Shaw, Davide Prandi, Benjamin D. Hopkins, Chantal Pauli
Supplementary Table 5. Patient B Single and buparlisib Combination High Throughput Drug Screen.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114e5e6528bcdf7c69d82fe41752773a
https://doi.org/10.1158/2159-8290.22531856
https://doi.org/10.1158/2159-8290.22531856
Autor:
Christopher J. Kemp, Carla Grandori, Elizabeth M. Swisher, Tan A. Ince, Robert L. Diaz, Rachele Rosati, Grace Durenberger, Kay E. Gurley, Russell Moser, Reid Shaw, Goldie Y.L. Lui, Shogo Shigeta
Supplementary Figure 2. Gene Ontology (GO) enrichment analysis indicates OCI-C5x cells are more vulnerable to epigenetic interventions than OCI-P5x cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2354bb286dbcd1d1d9e63161bd05f9
https://doi.org/10.1158/1535-7163.22522126.v1
https://doi.org/10.1158/1535-7163.22522126.v1
Autor:
Mark A. Rubin, Lewis C. Cantley, Carla Grandori, Christopher J. Kemp, Francesca Demichelis, Himisha Beltran, Olivier Elemento, Brady Bernard, Vijayakrishna K. Gadi, Brooke E. Emerling, Bishoy M. Faltas, Brian Robinson, Juan Miguel Mosquera, Rema Rao, David Pisapia, Joanna Triscott, Cynthia Cheung, Yelena Churakova, Terra J. McNary, Rachele Rosati, Loredana Puca, Michael Augello, Verena Sailer, Andrea Sboner, Tarcisio Fedrizzi, Reid Shaw, Davide Prandi, Benjamin D. Hopkins, Chantal Pauli
Supplementary Figures 1 - 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac1bebcc4ceb6fdefa1e71ac64f13ca
https://doi.org/10.1158/2159-8290.22531877.v1
https://doi.org/10.1158/2159-8290.22531877.v1
Autor:
Mark A. Rubin, Lewis C. Cantley, Carla Grandori, Christopher J. Kemp, Francesca Demichelis, Himisha Beltran, Olivier Elemento, Brady Bernard, Vijayakrishna K. Gadi, Brooke E. Emerling, Bishoy M. Faltas, Brian Robinson, Juan Miguel Mosquera, Rema Rao, David Pisapia, Joanna Triscott, Cynthia Cheung, Yelena Churakova, Terra J. McNary, Rachele Rosati, Loredana Puca, Michael Augello, Verena Sailer, Andrea Sboner, Tarcisio Fedrizzi, Reid Shaw, Davide Prandi, Benjamin D. Hopkins, Chantal Pauli
Supplementary Table 2. Drug Library Concentrations.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e3054b56827ed5e8ab3aba3d2b56c6a
https://doi.org/10.1158/2159-8290.22531871
https://doi.org/10.1158/2159-8290.22531871
Autor:
Mark A. Rubin, Lewis C. Cantley, Carla Grandori, Christopher J. Kemp, Francesca Demichelis, Himisha Beltran, Olivier Elemento, Brady Bernard, Vijayakrishna K. Gadi, Brooke E. Emerling, Bishoy M. Faltas, Brian Robinson, Juan Miguel Mosquera, Rema Rao, David Pisapia, Joanna Triscott, Cynthia Cheung, Yelena Churakova, Terra J. McNary, Rachele Rosati, Loredana Puca, Michael Augello, Verena Sailer, Andrea Sboner, Tarcisio Fedrizzi, Reid Shaw, Davide Prandi, Benjamin D. Hopkins, Chantal Pauli
Supplementary Table 1. Genomic analysis of 15 patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9952481a0f899e53e1573aec5861badd
https://doi.org/10.1158/2159-8290.22531874
https://doi.org/10.1158/2159-8290.22531874
Autor:
Mark A. Rubin, Lewis C. Cantley, Carla Grandori, Christopher J. Kemp, Francesca Demichelis, Himisha Beltran, Olivier Elemento, Brady Bernard, Vijayakrishna K. Gadi, Brooke E. Emerling, Bishoy M. Faltas, Brian Robinson, Juan Miguel Mosquera, Rema Rao, David Pisapia, Joanna Triscott, Cynthia Cheung, Yelena Churakova, Terra J. McNary, Rachele Rosati, Loredana Puca, Michael Augello, Verena Sailer, Andrea Sboner, Tarcisio Fedrizzi, Reid Shaw, Davide Prandi, Benjamin D. Hopkins, Chantal Pauli
Supplementary Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765b749351fdd2b2fc5615eb34bb6340
https://doi.org/10.1158/2159-8290.22531847.v1
https://doi.org/10.1158/2159-8290.22531847.v1