Investigation on the chemoenzymatic synthesis of threo- and erythro-β-hydroxy-l-glutamic acid derivatives

Autor: Sergio Riva, Carlo De Micheli, Pietro Magrone, Gabriella Roda, Francesca Sagui, Rachele Pizzoli

Publikováno v: Journal of molecular catalysis. B, Enzymatic
75 (2012): 27–34. doi:10.1016/j.molcatb.2011.11.004
info:cnr-pdr/source/autori:Sagui, Francesca; De Micheli, Carlo; Roda, Gabriella; Magrone, Pietro; Pizzoli, Rachele; Riva, Sergio/titolo:Investigation on the chemoenzymatic synthesis of threo-and erythro-beta-hydroxy-L-glutamic acid derivatives/doi:10.1016%2Fj.molcatb.2011.11.004/rivista:Journal of molecular catalysis. B, Enzymatic (Print)/anno:2012/pagina_da:27/pagina_a:34/intervallo_pagine:27–34/volume:75

A derivative of the malonic semialdehyde was transformed by means of a bioconversion catalyzed by the enzyme L-threonine aldolase from E. coli into a 6:4 epimeric mixture of two precursors of beta-hydroxy glutamic acid. The enzyme was selective for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7280ce0525ce408edab5dda18cd0ddc8
https://doi.org/10.1016/j.molcatb.2011.11.004