Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Rachel Weil"'
Autor:
Matthew E. Randolph, Marwa Afifi, Aparna Gorthi, Rachel Weil, Breelyn A. Wilky, Joshua Weinreb, Paul Ciero, Natalie ter Hoeve, Paul J. van Diest, Venu Raman, Alexander J.R. Bishop, David M. Loeb
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108925- (2024)
Summary: We previously demonstrated that RNA helicase DDX3X (DDX3) can be a therapeutic target in Ewing sarcoma (EWS), but its role in EWS biology remains unclear. The present work demonstrates that DDX3 plays a unique role in DNA damage repair (DDR)
Externí odkaz:
https://doaj.org/article/feee3811ebda42bda24ca7644f0ec5fe
Autor:
Rachel Weil, David Loeb
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Immunotherapies are a promising therapeutic option, yet for a variety of reasons, these treatments have achieved limited success against sarcomas. The immunosuppressive tumor microenvironment (TME) of sarcomas as well as lack of predictive biomarkers
Externí odkaz:
https://doaj.org/article/63a714f72205414e9e992c18e0d06039
Autor:
Walter Rayford, Alp Tuna Beksac, Jordan Alger, Mohammed Alshalalfa, Mohsen Ahmed, Irtaza Khan, Ugo G. Falagario, Yang Liu, Elai Davicioni, Daniel E. Spratt, Edward M. Schaeffer, Felix Y. Feng, Brandon Mahal, Paul L. Nguyen, Robert B. Den, Mark D. Greenberger, Randy Bradley, Justin M. Watson, Matthew Beamer, Lambros Stamatakis, Darrell J. Carmen, Shivanshu Awasthi, Jonathan Hwang, Rachel Weil, Harri Merisaari, Nihal Mohamed, Leslie A. Deane, Dimple Chakravarty, Kamlesh K. Yadav, Kosj Yamoah, Sujit S. Nair, Ashutosh K. Tewari
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Walter Rayford, Alp Tuna Beksac et al. investigated gene expression alterations in African-American and European-American men who underwent radical prostatectomy for prostate cancer. The observed differences include higher expression of inflammation
Externí odkaz:
https://doaj.org/article/8d16165e890d4d0585cbc92f6aeacd1e
Autor:
Alp Tuna Beksac, Parita Ratnani, Zachary Dovey, Sneha Parekh, Ugo Falagario, Reza Roshandel, Stanislaw Sobotka, Deepshikha Kewlani, Avery Davis, Rachel Weil, Hafis Bashorun, Ivan Jambor, Sara Lewis, Kenneth Haines, Ashutosh K. Tewari
Publikováno v:
Cancer Reports, Vol 5, Iss 3, Pp n/a-n/a (2022)
Abstract Background Active surveillance (AS) is the reference standard treatment for the management of low risk prostate cancer (PCa). Accurate assessment of tumor aggressiveness guides recruitment to AS programs to avoid conservative treatment of in
Externí odkaz:
https://doaj.org/article/c4591c2304804f61bac1de0086369898
Publikováno v:
Haematologica, Vol 107, Iss 3 (2021)
DEAD-box Helicase 41 (DDX41) is a recently identified factor mutated in hematologic malignancies whose function in hematopoiesis is unknown. Using an in vivo model of Ddx41 deficiency, we unveiled a critical role for this helicase in regulating eryth
Externí odkaz:
https://doaj.org/article/4cd34de674f44805b99fb798f4d8b85a
Autor:
Rachel Weil
Stories of plots, sham plots, and the citizen-informers who discovered them are at the center of Rachel Weil's compelling study of the turbulent decade following the Revolution of 1688. Most studies of the Glorious Revolution focus on its causes or l
Autor:
Dimple Chakravarty, Randy V. Bradley, Ashutosh K. Tewari, Irtaza Khan, Paul L. Nguyen, Elai Davicioni, Yang Liu, Justin Watson, Walter Rayford, Daniel E. Spratt, Shivanshu Awasthi, Mark D. Greenberger, Sujit S. Nair, Felix Y. Feng, Leslie A. Deane, Rachel Weil, Mohammed Alshalalfa, Edward M. Schaeffer, Kamlesh K Yadav, Ugo Falagario, Nihal Mohamed, Alp Tuna Beksac, Lambros Stamatakis, Mohsen Ahmed, Robert B. Den, Brandon A. Mahal, Harri Merisaari, Jordan Alger, Darrell J. Carmen, Kosj Yamoah, Matthew Beamer, Jonathan Hwang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology
Communications Biology
Racial disparities in prostate cancer have not been well characterized on a genomic level. Here we show the results of a multi-institutional retrospective analysis of 1,152 patients (596 African-American men (AAM) and 556 European-American men (EAM))
Autor:
Lauren Fiechtner, Rachel Weil, Laura Travis, Desiree Sierra Velez, Rachel M. Zack, Molly Babbin, Catherine Drennan Lynn, Daniel J. Taitelbaum
Publikováno v:
Am J Public Health
Autor:
Rachel Weil
Publikováno v:
The Historical Journal. 65:537-539
In 1756, the young John Howard set out for Portugal. His ship was taken by a privateer, and Howard became a prisoner of war in France. Twenty years later, he launched the movement for prison reform in Britain. Renaud Morieux challenges historians to