Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rachel Wai Sum Li"'
Autor:
Rachel Wai Sum Li, Cui Yang, Shun Wan Chan, Maggie Pui Man Hoi, Simon Ming Yuen Lee, Yiu Wa Kwan, George Pak Heng Leung
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123043 (2015)
BACKGROUND:The use of abacavir has been linked with increased cardiovascular risk in patients with human immunodeficiency virus infection; however, the mechanism involved remains unclear. We hypothesize that abacavir may impair endothelial function.
Externí odkaz:
https://doaj.org/article/2c92d8f52a684172a0860240c6eb3857
Autor:
Sai Wang Seto, Alice Lai Shan Au, Christina Chui Wa Poon, Qian Zhang, Rachel Wai Sum Li, John Hok Keung Yeung, Siu Kai Kong, Sai Ming Ngai, Song Wan, Ho Pui Ho, Simon Ming Yuen Lee, Maggie Pui Man Hoi, Shun Wan Chan, George Pak Heng Leung, Yiu Wa Kwan
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66404 (2013)
BackgroundStatins (3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors) consumption provides beneficial effects on cardiovascular systems. However, effects of statins on vascular KATP channel gatings are unknown.MethodsPig left ante
Externí odkaz:
https://doaj.org/article/1ea445f0492142abb247dac942149975
Autor:
Rachel Wai Sum Li, Renkai Li, Jingjing Li, Simon Ming-Yuen Lee, George P.H. Leung, Sai Wang Seto, Emily S. W. Wong
Publikováno v:
European Journal of Pharmacology. 905:174190
Narirutin is one of the most common flavanones found in citrus fruits. The vascular effects of its analogues naringenin and naringin have been reported but its effects on the cardiovascular system are largely unknown. In this study, relaxation effect
Autor:
George P.H. Leung, Shun Wan Chan, Chung Ming Tse, Philip Chiu Tsun Tang, Rachel Wai Sum Li, Simon Ming-Yuen Lee, Maggie Pui Man Hoi, Cui Yang, Yiu Wa Kwan
Publikováno v:
European Journal of Pharmacology. 791:544-551
Equilibrative nucleoside transporters (ENTs) play a crucial role in the transport of nucleoside and nucleoside analogues, which are important for nucleotide synthesis and chemotherapy. In addition, ENTs regulate extracellular adenosine levels in the
Autor:
Rachel Wai Sum Li, Sophie Y.T. Lin, Cui Yang, Albert S.M. Sit, Eva Y.W. Ho, George P.H. Leung
Publikováno v:
Journal of Cardiovascular Pharmacology. 59:10-15
Adenosine modulates various vascular functions such as vasodilatation and anti-inflammation. The local concentration of adenosine in the vicinity of adenosine receptors is fine tuned by 2 classes of nucleoside transporters: equilibrative nucleoside t
Autor:
Rachel Wai Sum Li, Shun Wan Chan, Wayne Yuk-Wai Lee, Christina Chui Wa Poon, Sai-Ming Ngai, John H.K. Yeung, Ho-Pui Ho, Sai Wang Seto, Siu Kai Kong, Qian Zhang, Alice Lai Shan Au, George P.H. Leung, Simon Ming-Yuen Lee, Yiu Wa Kwan
Publikováno v:
British Journal of Pharmacology. 161:1086-1098
BACKGROUND AND PURPOSE We evaluated the role(s) of monoamine oxidase (MAO)-mediated H2O2 generation on 5-hydroxytryptamine (5-HT)-induced tension development of isolated basilar artery of spontaneously hypertensive rats (SHR) and normotensive Wistar-
Autor:
Sai Wang Seto, Christina Chui Wa Poon, Yiu Wa Kwan, Siu Kai Kong, Ho-Pui Ho, Simon Ming-Yuen Lee, Rachel Wai Sum Li, Sai-Ming Ngai, George P.H. Leung, Shun Wan Chan, Maggie Pui Man Hoi
Publikováno v:
European journal of pharmacology. 767
In this study, we evaluated the anabolic effect and the underlying cellular mechanisms involved of vitamin K2 (10 nM) and 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) (10 nM), alone and in combination, on primary osteoblasts harvested from the iliac cres
Autor:
Luchen Shan, George P.H. Leung, Yiu Wa Kwan, Alex Chun Cheung, Rachel Wai Sum Li, King-Ho Cheung, Cui Yang, Zaijun Zhang, Shun Wan Chan, Simon Ming-Yuen Lee, Maggie Pui Man Hoi, Yuqiang Wang
Publikováno v:
European journal of pharmacology. 761
Danshen (Radix Salviae miltiorrhizae) and ChuanXiong (Ligusticum wallichii) are two traditional herbal medicines commonly used in China for the treatment of cardiovascular diseases. The active components in Danshen and ChuanXiong are Danshensu (DSS,
Autor:
Shun Wan Chan, Yiu Wa Kwan, George P.H. Leung, Simon Ming-Yuen Lee, Cui Yang, Rachel Wai Sum Li
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Frontiers in Pharmacology
Frontiers in Pharmacology
The serotonin (5-HT) uptake system is supposed to play a crucial part in vascular functions by "fine-tuning" the local concentration of 5-HT in the vicinity of 5-HT(2) receptors in vascular smooth muscle cells. In this study, the mechanism of 5-HT up
Autor:
Rachel Wai Sum Li, Shun Wan Chan, Yiu Wa Kwan, Tsz Yan Lam, George P.H. Leung, Wayne Yuk-Wai Lee, Simon Ming-Yuen Lee, Alice Lai Shan Au, Sai-Ming Ngai, Christina Chui Wa Poon, Sai Wang Seto, Penelope M.Y. Or, John H.K. Yeung
Publikováno v:
The Journal of nutritional biochemistry. 21(9)
Folic acid supplementation provides beneficial effects on endothelial functions in patients with hyperhomocysteinemia. However, its effects on vascular functions under diabetic conditions are largely unknown. Therefore, the effect(s) of folic acid (5