Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rachel V. Jimenez"'
Autor:
Rachel V. Jimenez, Alexander J. Szalai
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated with trauma and infectious and non-infectio
Externí odkaz:
https://doaj.org/article/5de4714ca3fd419a9a945e99d7f1093a
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Previously we established that human C-reactive protein (CRP) exacerbates mouse acute kidney injury and that the effect was associated with heightened renal accumulation of myeloid derived cells with suppressor functions (MDSC). Herein we provide dir
Externí odkaz:
https://doaj.org/article/ed00b84877704a9da4dbbc60ecd08a4d
Autor:
Rachel V. Jimenez, Tyler T. Wright, Nicholas R. Jones, Jianming Wu, Andrew W. Gibson, Alexander J. Szalai
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
C-reactive protein (CRP) is the prototypical acute phase reactant, increasing in blood concentration rapidly and several-fold in response to inflammation. Recent evidence indicates that CRP has an important physiological role even at low, baseline le
Externí odkaz:
https://doaj.org/article/1c3cbd2a1f1942b4a520d6f58a501078
Autor:
Tyler T Wright, Rachel V. Jimenez, Todd E. Morgan, Namrata Bali, Xiaogang Hou, Mark A. McCrory, Caleb E. Finch, Alexander J. Szalai
Publikováno v:
Autoimmune Diseases, Vol 2015 (2015)
We recently demonstrated that human C-reactive protein (CRP), expressed hepatically in transgenic mice (CRPtg), improved the outcome of experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). The liver is the prima
Externí odkaz:
https://doaj.org/article/48aa33d3701c484b843f733b352e3c30
Autor:
Alexander J. Szalai, Rachel V. Jimenez
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Frontiers in Immunology
Frontiers in Immunology
In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated with trauma and infectious and non-infectio
Autor:
Andrew W. Gibson, Alexander J. Szalai, Tyler T. Wright, Nicholas R. Jones, Rachel V. Jimenez, Jianming Wu
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
C-reactive protein (CRP) is the prototypical acute phase reactant, increasing in blood concentration rapidly and several-fold in response to inflammation. Recent evidence indicates that CRP has an important physiological role even at low, baseline le
Autor:
Rachel V. Jimenez, Todd E. Morgan, Caleb E. Finch, Tyler T. Wright, Mark A. McCrory, Namrata Bali, Xiaogang Hou, Alexander J. Szalai
Publikováno v:
Autoimmune Diseases, Vol 2015 (2015)
Autoimmune Diseases
Autoimmune Diseases
We recently demonstrated that human C-reactive protein (CRP), expressed hepatically in transgenic mice (CRPtg), improved the outcome of experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). The liver is the prima
Autor:
Rachel V Jimenez, Alexander J Szalai
Publikováno v:
The Journal of Immunology. 198:222.8-222.8
Recently, we provided evidence that C-reactive protein (CRP) plays a causal role in acute kidney injury (AKI) i.e., human CRP exacerbates AKI in CRP transgenic mice (CRPtg) and AKI severity is lessened in CRP knockout mice. The CRP effect in CRPtg wa